MX2012001194A - Peptidos tau antigenicos y usos de los mismos. - Google Patents
Peptidos tau antigenicos y usos de los mismos.Info
- Publication number
- MX2012001194A MX2012001194A MX2012001194A MX2012001194A MX2012001194A MX 2012001194 A MX2012001194 A MX 2012001194A MX 2012001194 A MX2012001194 A MX 2012001194A MX 2012001194 A MX2012001194 A MX 2012001194A MX 2012001194 A MX2012001194 A MX 2012001194A
- Authority
- MX
- Mexico
- Prior art keywords
- tau peptides
- antigenic tau
- immunogens
- compositions
- antigenic
- Prior art date
Links
- 101000854943 Enterobacteria phage T4 Valyl-tRNA ligase modifier Proteins 0.000 title abstract 2
- 230000000890 antigenic effect Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente divulgación se refiere a nuevos inmunógenos y composiciones que comprenden un péptido tau antigénico, preferentemente unido a un vehículo inmunogénico para su uso en el tratamiento de trastornos neurológicos relacionados con tau; la divulgación se refiere además a procedimientos para la producción de estos inmunógenos y composiciones y a su uso en medicina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22986009P | 2009-07-30 | 2009-07-30 | |
| PCT/IB2010/053313 WO2011013034A1 (en) | 2009-07-30 | 2010-07-20 | Antigenic tau peptides and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012001194A true MX2012001194A (es) | 2012-03-07 |
Family
ID=42941871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012001194A MX2012001194A (es) | 2009-07-30 | 2010-07-20 | Peptidos tau antigenicos y usos de los mismos. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20110177109A1 (es) |
| EP (1) | EP2459214A1 (es) |
| JP (1) | JP2013500326A (es) |
| KR (2) | KR20120049900A (es) |
| CN (1) | CN102596236B (es) |
| AR (1) | AR078085A1 (es) |
| AU (1) | AU2010277254B2 (es) |
| CA (1) | CA2768346A1 (es) |
| CO (1) | CO6612199A2 (es) |
| IN (1) | IN2012DN00446A (es) |
| MX (1) | MX2012001194A (es) |
| NZ (2) | NZ618391A (es) |
| PE (1) | PE20120817A1 (es) |
| RU (2) | RU2518291C2 (es) |
| SG (1) | SG177637A1 (es) |
| TW (2) | TWI461209B (es) |
| WO (1) | WO2011013034A1 (es) |
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| PE20110998A1 (es) | 2008-12-09 | 2012-02-10 | Coley Pharm Group Inc | Oligonucleotidos inmunoestimuladores |
| US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
| UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
| EP2440234A4 (en) | 2009-06-10 | 2013-11-06 | Univ New York | IMMUNOLOGICAL AIMING OF PATHOLOGICAL TAU PROTEINS |
| AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
| HUE027649T2 (en) | 2010-10-07 | 2016-10-28 | Ac Immune Sa | Antibodies recognising phospho-tau |
| ES2714692T3 (es) | 2011-01-31 | 2019-05-29 | Tau Bio Logic Corp | Tratamiento de tauopatías |
| AU2012282678B2 (en) | 2011-07-11 | 2016-03-03 | California Institute Of Technology | Akt-specific capture agents, compositions, and methods of using and making |
| MX339762B (es) | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
| MX354662B (es) | 2011-10-07 | 2018-03-14 | Ac Immune Sa | Anticuerpos fosfoespecificos que reconocen la tau. |
| AU2013243861A1 (en) | 2012-04-05 | 2014-10-23 | Ac Immune S.A. | Humanized Tau antibody |
| SG10201913370PA (en) * | 2012-07-03 | 2020-03-30 | Univ Washington | Antibodies to tau |
| WO2014028777A2 (en) | 2012-08-16 | 2014-02-20 | Ipierian, Inc. | Methods of treating a tauopathy |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| MX374811B (es) | 2013-03-15 | 2025-03-06 | Ac Immune Sa | Anticuerpos anti-tau y métodos de uso. |
| WO2015017280A1 (en) * | 2013-07-28 | 2015-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
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| TWI734975B (zh) | 2014-06-27 | 2021-08-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| CN107073297B (zh) | 2014-07-08 | 2021-09-14 | 纽约大学 | Tau显像配体和其在Tau蛋白病的诊断和治疗中的用途 |
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| US10344081B2 (en) | 2015-07-06 | 2019-07-09 | Ucb Biopharma Sprl | Tau-binding antibodies |
| ES3017796T3 (en) | 2015-07-15 | 2025-05-13 | California Inst Of Techn | Il-17f-specific capture agents and methods of using |
| WO2017027685A2 (en) | 2015-08-13 | 2017-02-16 | New York University | Antibody-based molecules specific for the truncated asp421 epitope of tau and their uses in the diagnosis and treatment of tauopathy |
| EP3519425B1 (en) | 2016-09-29 | 2024-02-28 | Indi Molecular, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same |
| GB201700487D0 (en) | 2017-01-11 | 2017-02-22 | Hermon-Taylor John | Diagnostic |
| CN111787942B (zh) * | 2017-10-25 | 2024-03-29 | 杨森制药公司 | 磷酸化Tau肽的组合物及其用途 |
| MX2020005555A (es) * | 2017-10-27 | 2020-08-20 | United Neuroscience | Construcciones inmunogenicas de peptidos de tau. |
| CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
| CN108314737B (zh) * | 2018-01-25 | 2021-03-16 | 中国科学院过程工程研究所 | 一种重组蛋白及其制备方法和应用 |
| CN110548135B (zh) * | 2018-05-31 | 2023-06-06 | 长春百克生物科技股份公司 | 磷酸化多肽抗原疫苗及其制备方法和应用 |
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| WO2020073121A1 (en) * | 2018-10-07 | 2020-04-16 | The University Of British Columbia | Conformation-specific epitopes in alpha-synuclein, antibodies thereto and methods related thereof |
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| KR20210125048A (ko) | 2019-02-08 | 2021-10-15 | 에이씨 이뮨 에스.에이. | 인산화 타우 펩티드 백신의 안전한 투여 방법 |
| US20200291391A1 (en) * | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
| US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
| CA3135170A1 (en) | 2019-04-05 | 2020-10-08 | Tauc3 Biologics Limited | Anti-tauc3 antibodies and uses thereof |
| BR112021021213A2 (pt) | 2019-04-24 | 2021-12-21 | Ac Immune Sa | Administração heteróloga de vacinas de tau |
| WO2020236969A1 (en) | 2019-05-20 | 2020-11-26 | Indi Molecular, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1) |
| KR20220034733A (ko) * | 2019-05-27 | 2022-03-18 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 타우의 입체형태-특이적 에피토프, 이에 대한 항체 및 이와 관련된 방법 |
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| US20030091593A1 (en) | 2001-09-14 | 2003-05-15 | Cytos Biotechnology Ag | In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles |
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| NZ537688A (en) * | 2002-07-19 | 2007-01-26 | Cytos Biotechnology Ag | Vaccine compositions containing amyloid beta1-6 antigen arrays for treating and/or attenuating Alzheimer's disease |
| WO2004053091A2 (en) | 2002-12-10 | 2004-06-24 | Lorantis Ltd. | STABILIZED IMMUNOGENIC HBc CHIMER PARTICLES |
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-
2010
- 2010-07-20 RU RU2012102701/10A patent/RU2518291C2/ru not_active IP Right Cessation
- 2010-07-20 PE PE2012000116A patent/PE20120817A1/es not_active Application Discontinuation
- 2010-07-20 SG SG2012002390A patent/SG177637A1/en unknown
- 2010-07-20 AU AU2010277254A patent/AU2010277254B2/en not_active Ceased
- 2010-07-20 KR KR1020127005415A patent/KR20120049900A/ko not_active Abandoned
- 2010-07-20 NZ NZ618391A patent/NZ618391A/en not_active IP Right Cessation
- 2010-07-20 EP EP10739402A patent/EP2459214A1/en not_active Withdrawn
- 2010-07-20 IN IN446DEN2012 patent/IN2012DN00446A/en unknown
- 2010-07-20 NZ NZ598356A patent/NZ598356A/en not_active IP Right Cessation
- 2010-07-20 KR KR1020137028550A patent/KR20130127547A/ko not_active Ceased
- 2010-07-20 MX MX2012001194A patent/MX2012001194A/es not_active Application Discontinuation
- 2010-07-20 WO PCT/IB2010/053313 patent/WO2011013034A1/en not_active Ceased
- 2010-07-20 CA CA2768346A patent/CA2768346A1/en not_active Abandoned
- 2010-07-20 CN CN201080040148.8A patent/CN102596236B/zh not_active Expired - Fee Related
- 2010-07-20 JP JP2012522292A patent/JP2013500326A/ja active Pending
- 2010-07-29 TW TW099125165A patent/TWI461209B/zh not_active IP Right Cessation
- 2010-07-29 TW TW103104138A patent/TW201436804A/zh unknown
- 2010-07-29 AR ARP100102753A patent/AR078085A1/es unknown
- 2010-07-29 US US12/846,719 patent/US20110177109A1/en not_active Abandoned
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2012
- 2012-02-15 CO CO12026764A patent/CO6612199A2/es unknown
-
2014
- 2014-03-31 RU RU2014112002/10A patent/RU2014112002A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN102596236A (zh) | 2012-07-18 |
| NZ618391A (en) | 2015-07-31 |
| RU2014112002A (ru) | 2015-10-10 |
| RU2012102701A (ru) | 2013-09-10 |
| TW201436804A (zh) | 2014-10-01 |
| SG177637A1 (en) | 2012-03-29 |
| KR20130127547A (ko) | 2013-11-22 |
| TWI461209B (zh) | 2014-11-21 |
| US20110177109A1 (en) | 2011-07-21 |
| CA2768346A1 (en) | 2011-02-03 |
| WO2011013034A4 (en) | 2011-04-28 |
| EP2459214A1 (en) | 2012-06-06 |
| RU2518291C2 (ru) | 2014-06-10 |
| KR20120049900A (ko) | 2012-05-17 |
| TW201106968A (en) | 2011-03-01 |
| AU2010277254A1 (en) | 2012-02-09 |
| IN2012DN00446A (es) | 2015-05-15 |
| CO6612199A2 (es) | 2013-02-01 |
| CN102596236B (zh) | 2015-06-24 |
| JP2013500326A (ja) | 2013-01-07 |
| AU2010277254B2 (en) | 2015-05-07 |
| WO2011013034A1 (en) | 2011-02-03 |
| AR078085A1 (es) | 2011-10-12 |
| PE20120817A1 (es) | 2012-07-07 |
| NZ598356A (en) | 2014-06-27 |
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