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MX2011011497A - Coaglomerados de manitol y de almidon granular comprimibles y de libre fluidez. - Google Patents

Coaglomerados de manitol y de almidon granular comprimibles y de libre fluidez.

Info

Publication number
MX2011011497A
MX2011011497A MX2011011497A MX2011011497A MX2011011497A MX 2011011497 A MX2011011497 A MX 2011011497A MX 2011011497 A MX2011011497 A MX 2011011497A MX 2011011497 A MX2011011497 A MX 2011011497A MX 2011011497 A MX2011011497 A MX 2011011497A
Authority
MX
Mexico
Prior art keywords
agglomerates
mannitol
compressible
flow
free
Prior art date
Application number
MX2011011497A
Other languages
English (en)
Other versions
MX358382B (es
Inventor
Alain Francois
Philippe Lefevre
Baptiste Boit
Damien Passe
Original Assignee
Roquette Freres
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roquette Freres filed Critical Roquette Freres
Publication of MX2011011497A publication Critical patent/MX2011011497A/es
Publication of MX358382B publication Critical patent/MX358382B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

La invención tiene por objeto coaglomerados de manitol cristalino y de almidón granular, caracterizado porque presentan una comprimibilidad, determinada según un ensayo A, superior a 120 N, de preferencia comprendida entre los 200 y 450 N, y una nota de fluidez, determinada según un ensayo B, comprendida entre 3 y 15 segundos, de preferencia comprendida entre 4 y 8 segundos.
MX2011011497A 2009-04-30 2010-04-28 Coaglomerados de manitol y de almidon granular comprimibles y de libre fluidez. MX358382B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0952894A FR2944971B1 (fr) 2009-04-30 2009-04-30 Coagglomerats de mannitol et d'amidon granulaire comprimables et a ecoulement libre
PCT/FR2010/050813 WO2010125313A1 (fr) 2009-04-30 2010-04-28 Coagglomerats de mannitol et d'amidon granulaire comprimables et a ecoulement libre

Publications (2)

Publication Number Publication Date
MX2011011497A true MX2011011497A (es) 2011-11-18
MX358382B MX358382B (es) 2018-08-15

Family

ID=41402540

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011011497A MX358382B (es) 2009-04-30 2010-04-28 Coaglomerados de manitol y de almidon granular comprimibles y de libre fluidez.

Country Status (13)

Country Link
US (4) US9937131B2 (es)
EP (1) EP2424508B1 (es)
JP (1) JP5676566B2 (es)
KR (2) KR20170012593A (es)
CN (1) CN102413819B (es)
AR (2) AR076519A1 (es)
BR (1) BRPI1014371B1 (es)
CA (1) CA2755992C (es)
ES (1) ES2795824T3 (es)
FR (1) FR2944971B1 (es)
MX (1) MX358382B (es)
RU (1) RU2540914C2 (es)
WO (1) WO2010125313A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2944971B1 (fr) * 2009-04-30 2012-09-07 Roquette Freres Coagglomerats de mannitol et d'amidon granulaire comprimables et a ecoulement libre
CN104770694B (zh) * 2015-04-15 2020-09-15 中国农业科学院农产品加工研究所 利用马铃薯冲调粉造粒设备进行造粒的方法
FR3038836B1 (fr) * 2015-07-17 2017-07-14 Roquette Freres Granules de mannitol pour compression directe
CA2916077C (en) * 2015-12-22 2023-06-20 Euro-Pharm International Canada Inc. Nicotine-containing solid oral formulations and uses thereof
JP2017158534A (ja) * 2016-03-07 2017-09-14 焼津水産化学工業株式会社 チップ状食品の製造方法及びチップ状食品
KR102151268B1 (ko) 2018-08-24 2020-09-02 주식회사 산하이앤씨 지하수정호 결합 복합 지열시스템 및 그 성능 평가방법
KR102191122B1 (ko) 2019-01-18 2020-12-16 엘지전자 주식회사 전동식 압축기
IT201900002857A1 (it) * 2019-02-27 2020-08-27 Ntc S R L Procedimento di riempimento di contenitori con una polvere
CN120076787A (zh) 2022-10-28 2025-05-30 罗盖特公司 用于配制湿气敏感性活性成分的化合物
CN116617406A (zh) * 2023-06-16 2023-08-22 齐鲁理工学院 一种微晶甘露醇药用辅料、硬胶囊及其制备方法
CN116509807B (zh) * 2023-07-04 2023-09-19 山东天力药业有限公司 一种甘露醇颗粒的制备方法
CN117503938B (zh) * 2023-11-24 2024-09-13 江苏西典药用辅料有限公司 直压型甘露醇的制备方法
CN117860688B (zh) * 2024-03-12 2024-05-31 山东天力药业有限公司 一种直压级甘露醇颗粒及其制备方法
CN118453884B (zh) * 2024-07-12 2024-09-27 山东天力药业有限公司 一种含甘露醇的药用辅料及其制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145146A (en) 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets
JPS6185331A (ja) * 1984-10-04 1986-04-30 Fuji Kagaku Kogyo Kk 直打用賦形薬の製造法
FR2640876B1 (es) * 1988-12-28 1993-09-24 Jouveinal Sa
DE3903217A1 (de) * 1989-02-03 1990-08-09 Boehringer Ingelheim Vetmed Verfahren zur herstellung fester pharmazeutischer zubereitungen
JPH0977669A (ja) * 1995-09-19 1997-03-25 Takeda Chem Ind Ltd ビタミンｂ群顆粒品の組成物およびその製造方法
US6235947B1 (en) * 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation
JPH10158153A (ja) * 1996-11-25 1998-06-16 Nippon Eranko Kk 医薬用硬質ゼラチンカプセル及びその製造方法
GB9802201D0 (en) * 1998-02-03 1998-04-01 Cerestar Holding Bv Free-flowable directly compressible starch as binder,disintegrant and filler for compresion tablets and hard gelatine capsules
CA2360102C (en) * 1999-02-15 2009-05-19 Sumitomo Pharmaceuticals Co., Ltd. Tablets disintegrating rapidly in the oral cavity
AU5248900A (en) * 1999-06-18 2001-01-09 Takeda Chemical Industries Ltd. Quickly disintegrating solid preparations
US6664389B1 (en) * 1999-10-01 2003-12-16 National Starch And Chemical Investment Holding Coporation Highly resistant granular starch
CA2342121C (fr) 2000-03-29 2010-05-25 Roquette Freres Mannitol pulverulent et son procede de preparation
FR2807034B1 (fr) 2000-03-29 2002-06-14 Roquette Freres Mannitol pulverulent et son procede de fabrication
ES2292414T3 (es) * 2000-07-27 2008-03-16 Roquette Freres Granulos a base de almidon y de lactosa.
US6544552B2 (en) * 2001-01-11 2003-04-08 Particle And Coating Technologies, Inc. Method of producing porous tablets with improved dissolution properties
DE10161402A1 (de) * 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
JP2004175795A (ja) * 2002-11-13 2004-06-24 Takeda Chem Ind Ltd 薬物の放出性に優れた医薬組成物
KR100535228B1 (ko) * 2003-03-11 2005-12-08 한국유나이티드제약 주식회사 란소프라졸함유 경질캅셀제의 제조방법
SE0301880D0 (sv) * 2003-06-25 2003-06-25 Astrazeneca Uk Ltd New drug delivery composition
CN101269055B (zh) * 2007-03-21 2011-12-14 北京德众万全药物技术开发有限公司 盐酸氨溴索口腔崩解片及其制备方法
CN101181404A (zh) * 2007-11-28 2008-05-21 南京海陵中药制药工艺技术研究有限公司 一种治疗咽部疾病的口含片及制备方法
FR2933299B1 (fr) * 2008-07-04 2012-02-03 Roquette Freres Mannitol orodispersible
FR2944971B1 (fr) * 2009-04-30 2012-09-07 Roquette Freres Coagglomerats de mannitol et d'amidon granulaire comprimables et a ecoulement libre

Also Published As

Publication number Publication date
EP2424508B1 (fr) 2020-03-11
CA2755992A1 (fr) 2010-11-04
JP2012525361A (ja) 2012-10-22
CN102413819A (zh) 2012-04-11
MX358382B (es) 2018-08-15
US20220008343A1 (en) 2022-01-13
CN102413819B (zh) 2015-09-09
US20120053249A1 (en) 2012-03-01
FR2944971B1 (fr) 2012-09-07
US11364204B2 (en) 2022-06-21
KR101867621B1 (ko) 2018-06-15
BRPI1014371B1 (pt) 2021-07-27
RU2540914C2 (ru) 2015-02-10
US20200155460A1 (en) 2020-05-21
AR118760A2 (es) 2021-10-27
US20170281550A1 (en) 2017-10-05
KR20170012593A (ko) 2017-02-02
US9937131B2 (en) 2018-04-10
FR2944971A1 (fr) 2010-11-05
KR20120016075A (ko) 2012-02-22
WO2010125313A1 (fr) 2010-11-04
BRPI1014371A2 (pt) 2020-09-24
RU2011148600A (ru) 2013-06-10
JP5676566B2 (ja) 2015-02-25
EP2424508A1 (fr) 2012-03-07
ES2795824T3 (es) 2020-11-24
AR076519A1 (es) 2011-06-15
CA2755992C (fr) 2018-04-03

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