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MX2011011229A - Metodo para reducir la presion intraocular en los seres humanos. - Google Patents

Metodo para reducir la presion intraocular en los seres humanos.

Info

Publication number
MX2011011229A
MX2011011229A MX2011011229A MX2011011229A MX2011011229A MX 2011011229 A MX2011011229 A MX 2011011229A MX 2011011229 A MX2011011229 A MX 2011011229A MX 2011011229 A MX2011011229 A MX 2011011229A MX 2011011229 A MX2011011229 A MX 2011011229A
Authority
MX
Mexico
Prior art keywords
intraocular pressure
humans
reducing intraocular
formula
compounds
Prior art date
Application number
MX2011011229A
Other languages
English (en)
Inventor
Shikha Barman
Rudolf A Baumgartner
Original Assignee
Inotek Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43030847&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011011229(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Inotek Pharmaceuticals Corp filed Critical Inotek Pharmaceuticals Corp
Publication of MX2011011229A publication Critical patent/MX2011011229A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Prostheses (AREA)

Abstract

En la presente se proporcionan compuestos de Fórmula I, composiciones que comprenden una cantidad eficaz de un compuesto de Fórmula I y métodos para reducir la presión intraocular que comprenden administrar una cantidad eficaz de compuestos de Fórmula 1 a un individuo que lo necesita.
MX2011011229A 2009-05-01 2010-04-30 Metodo para reducir la presion intraocular en los seres humanos. MX2011011229A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17465509P 2009-05-01 2009-05-01
US21999009P 2009-06-24 2009-06-24
PCT/US2010/033112 WO2010127210A1 (en) 2009-05-01 2010-04-30 Method of reducing intraocular pressure in humans

Publications (1)

Publication Number Publication Date
MX2011011229A true MX2011011229A (es) 2011-11-18

Family

ID=43030847

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011011229A MX2011011229A (es) 2009-05-01 2010-04-30 Metodo para reducir la presion intraocular en los seres humanos.

Country Status (25)

Country Link
US (2) US8470800B2 (es)
EP (1) EP2424546B1 (es)
JP (1) JP5778663B2 (es)
KR (1) KR101757940B1 (es)
CN (1) CN102413832B (es)
AU (1) AU2010242943B2 (es)
BR (1) BRPI1009971A2 (es)
CA (1) CA2762064A1 (es)
CL (1) CL2011002675A1 (es)
DK (1) DK2424546T3 (es)
EA (1) EA024042B1 (es)
ES (1) ES2554684T3 (es)
HR (1) HRP20151200T1 (es)
HU (1) HUE028068T2 (es)
IL (1) IL216081A (es)
MX (1) MX2011011229A (es)
MY (1) MY159244A (es)
NZ (1) NZ596428A (es)
PL (1) PL2424546T3 (es)
PT (1) PT2424546E (es)
RS (1) RS54378B1 (es)
SG (1) SG175346A1 (es)
SI (1) SI2424546T1 (es)
SM (1) SMT201500295B (es)
WO (1) WO2010127210A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008062567A1 (de) 2008-12-16 2010-06-17 Bayer Schering Pharma Aktiengesellschaft Dipeptoid-Prodrugs und ihre Verwendung
DE102009006602A1 (de) * 2009-01-29 2010-08-05 Bayer Schering Pharma Aktiengesellschaft Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs
PH12012500661A1 (en) * 2009-10-26 2012-10-22 Inotek Pharmaceuticals Corp Ophthalmic formulation and method of manufacture thereof
EP2523669B1 (en) * 2010-01-11 2016-12-07 Inotek Pharmaceuticals Corporation Combination, kit and method of reducing intraocular pressure
LT2555775T (lt) 2010-03-19 2017-04-25 Inotek Pharmaceuticals Corporation Adenozino a1 agonistų ir karboanhidrazės inhibitorių derinio kompozicijos, skirtos akispūdžio mažinimui
ES2613255T3 (es) 2010-03-19 2017-05-23 Inotek Pharmaceuticals Corporation Composiciones combinadas de agonistas de adenosina A1 y bloqueadores de receptores ß-adrenérgicos no selectivos para reducir la presión intraocular
JP2013523739A (ja) 2010-03-26 2013-06-17 イノテック ファーマシューティカルズ コーポレイション Ｎ６−シクロペンチルアデノシン（ｃｐａ）、ｃｐａ誘導体またはそれらのプロドラッグを用いてヒトにおける眼内圧を低下させる方法
DE102010030688A1 (de) 2010-06-30 2012-01-05 Bayer Schering Pharma Aktiengesellschaft Substituierte Dicyanopyridine und ihre Verwendung
US20120058983A1 (en) * 2010-09-02 2012-03-08 Bayer Pharma Aktiengesellschaft Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension
NZ627778A (en) * 2012-01-26 2017-01-27 Inotek Pharmaceuticals Corp Anhydrous polymorphs of (2r,3s,4r,5r)-5-(6-(cyclopentylamino)-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)} methyl nitrate and processes of preparation thereof
BR112015021870A2 (pt) 2013-03-15 2017-07-18 Inotek Pharmaceuticals Corp formulações oftálmicas
KR20170123605A (ko) * 2014-12-03 2017-11-08 이노텍 파마슈티컬스 코포레이션 황반 변성의 예방, 완화 또는 치료 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103087133B (zh) * 2004-05-26 2016-09-14 伊诺泰克制药公司 嘌呤衍生物作为腺苷a1受体激动剂及其用法
CN101010085B (zh) * 2004-05-26 2012-12-26 伊诺泰克制药公司 嘌呤衍生物作为腺苷a1受体激动剂及其用法
NZ568392A (en) * 2005-11-30 2011-07-29 Inotek Pharmaceuticals Corp Purine derivatives and methods of use thereof
PH12012500661A1 (en) * 2009-10-26 2012-10-22 Inotek Pharmaceuticals Corp Ophthalmic formulation and method of manufacture thereof
EP2523669B1 (en) * 2010-01-11 2016-12-07 Inotek Pharmaceuticals Corporation Combination, kit and method of reducing intraocular pressure
LT2555775T (lt) * 2010-03-19 2017-04-25 Inotek Pharmaceuticals Corporation Adenozino a1 agonistų ir karboanhidrazės inhibitorių derinio kompozicijos, skirtos akispūdžio mažinimui
ES2613255T3 (es) * 2010-03-19 2017-05-23 Inotek Pharmaceuticals Corporation Composiciones combinadas de agonistas de adenosina A1 y bloqueadores de receptores ß-adrenérgicos no selectivos para reducir la presión intraocular

Also Published As

Publication number Publication date
EA024042B1 (ru) 2016-08-31
HUE028068T2 (en) 2016-11-28
HRP20151200T1 (hr) 2016-01-15
US20130217643A1 (en) 2013-08-22
US20100279970A1 (en) 2010-11-04
ES2554684T3 (es) 2015-12-22
SMT201500295B (it) 2016-01-08
PL2424546T3 (pl) 2016-04-29
MY159244A (en) 2016-12-30
CN102413832A (zh) 2012-04-11
US8470800B2 (en) 2013-06-25
WO2010127210A1 (en) 2010-11-04
SI2424546T1 (sl) 2016-02-29
JP2012525437A (ja) 2012-10-22
EA201171339A1 (ru) 2012-05-30
CA2762064A1 (en) 2010-11-04
EP2424546B1 (en) 2015-10-28
EP2424546A1 (en) 2012-03-07
RS54378B1 (sr) 2016-04-28
AU2010242943A1 (en) 2011-12-01
IL216081A (en) 2015-11-30
CN102413832B (zh) 2015-11-25
HK1167599A1 (en) 2012-12-07
AU2010242943B2 (en) 2016-09-29
KR101757940B1 (ko) 2017-07-13
NZ596428A (en) 2014-03-28
IL216081A0 (en) 2012-01-31
PT2424546E (pt) 2015-12-23
JP5778663B2 (ja) 2015-09-16
SG175346A1 (en) 2011-11-28
EP2424546A4 (en) 2013-01-23
DK2424546T3 (en) 2015-12-14
BRPI1009971A2 (pt) 2016-03-15
KR20120017026A (ko) 2012-02-27
CL2011002675A1 (es) 2012-06-01

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