[go: up one dir, main page]

MX2011011079A - Procedimiento para preparar compuestos de isoxazolina sustituidos y sus precursores. - Google Patents

Procedimiento para preparar compuestos de isoxazolina sustituidos y sus precursores.

Info

Publication number
MX2011011079A
MX2011011079A MX2011011079A MX2011011079A MX2011011079A MX 2011011079 A MX2011011079 A MX 2011011079A MX 2011011079 A MX2011011079 A MX 2011011079A MX 2011011079 A MX2011011079 A MX 2011011079A MX 2011011079 A MX2011011079 A MX 2011011079A
Authority
MX
Mexico
Prior art keywords
formula
compounds
precursors
isoxazoline compounds
substituted isoxazoline
Prior art date
Application number
MX2011011079A
Other languages
English (en)
Inventor
Michael Rack
Florian Kaiser
Karsten Koerber
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of MX2011011079A publication Critical patent/MX2011011079A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a un nuevo método para preparar compuestos de estireno halogenados de la fórmula (VIII) (ver fórmula (VIII)) que son precursores en el procedimiento de síntesis de compuestos de isoxazolina sustituidos de la fórmula (I). (ver fórmula (I)) en la que R1 a R5, R8 y R9 se describen como en la descripción. La presente invención se refiere además a la síntesis de compuestos de la fórmula (1) a partir de acetofenonas. Los estirenos deseados de la fórmula son preparados a partir de la acetofenona sustituida apropiada. A más de esto, se hacen reaccionar bromoanilinas con formoxima. Las oximas obtenidas son sometidas a una cicloadición con los estirenos y dan isoxazolinas. Se pueden entonces preparar compuestos de la fórmula (I) haciendo reaccionar las isoxazolinas con una aminación carbonilativa catalizada por paladio.
MX2011011079A 2009-04-30 2010-04-29 Procedimiento para preparar compuestos de isoxazolina sustituidos y sus precursores. MX2011011079A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09159246 2009-04-30
PCT/EP2010/055773 WO2010125130A1 (en) 2009-04-30 2010-04-29 Process for preparing substituted isoxazoline compounds and their precursors

Publications (1)

Publication Number Publication Date
MX2011011079A true MX2011011079A (es) 2011-11-04

Family

ID=42227851

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011011079A MX2011011079A (es) 2009-04-30 2010-04-29 Procedimiento para preparar compuestos de isoxazolina sustituidos y sus precursores.

Country Status (10)

Country Link
US (1) US8853410B2 (es)
EP (1) EP2424862B1 (es)
JP (1) JP2012525353A (es)
CN (1) CN102414202B (es)
BR (1) BRPI1006679B1 (es)
DK (1) DK2424862T3 (es)
ES (1) ES2524970T3 (es)
IL (1) IL215519A (es)
MX (1) MX2011011079A (es)
WO (1) WO2010125130A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0917188A2 (pt) 2008-08-22 2015-08-18 Syngenta Participations Ag Compostos inseticidas
BRPI0917369A2 (pt) 2008-08-22 2015-08-04 Syngenta Participations Ag Compostos inseticidas
EA201100421A1 (ru) 2008-09-04 2011-10-31 Зингента Партисипейшнс Аг Инсектицидные соединения
MX2012014439A (es) 2010-06-23 2013-02-07 Basf Se Proceso para producir compuestos aromaticos de carbonilo e imina.
US9006447B2 (en) 2010-11-03 2015-04-14 Basf Se Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes
CN102659705A (zh) * 2012-04-06 2012-09-12 华东师范大学 3，4-二取代异噁唑类化合物的合成方法
BR112017007508B1 (pt) * 2014-10-14 2021-02-02 Syngenta Participations Ag processo para a preparação de trifluoroacetofenonas substituídas por halo
CN105061304A (zh) * 2015-06-05 2015-11-18 沈阳科创化学品有限公司 制备异噁唑啉类化合物及其中间体的方法
WO2018166855A1 (en) 2017-03-16 2018-09-20 Basf Se Heterobicyclic substituted dihydroisoxazoles
WO2018191871A1 (zh) * 2017-04-18 2018-10-25 苏州大学张家港工业技术研究院 一种异恶唑啉衍生物的制备方法
CN107353189A (zh) * 2017-07-06 2017-11-17 荆门医药工业技术研究院 制备3, 5‑二氯‑a‑（三氟甲基）苯乙烯的方法
CN107915754A (zh) * 2017-10-30 2018-04-17 浙江工业大学上虞研究院有限公司 一种纳斯特试剂的催化合成方法及其应用
AU2019369659A1 (en) 2018-10-29 2021-04-29 Basf Se Process for preparation of optically enriched aldol compounds
EP3891113B1 (en) 2018-12-04 2022-08-17 Basf Se Process for preparation of 5-bromo-1,3-dichloro-2-fluoro-benzene
US12497370B2 (en) 2019-12-18 2025-12-16 Elanco Tiergesundheit Ag Isoxazoline derivatives
US20230174551A1 (en) * 2020-05-05 2023-06-08 Basf Se Condensed isoxazoline derivatives and their use as herbicides
CN113024390B (zh) * 2021-02-22 2023-12-05 台州臻挚生物科技有限公司 3’,5’-二氯-2,2,2-三氟苯乙酮衍生物的合成方法
CN116640071B (zh) * 2023-05-04 2024-08-30 四川青木制药有限公司 一种制备2-甲基4-甲醛肟基苯甲酸及其酯类衍生物的方法
CN117903074A (zh) * 2024-01-15 2024-04-19 郑州手性药物研究院有限公司 一种4,5-二氢异噁唑-3-羧酸类化合物的制备方法

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58216130A (ja) * 1982-05-25 1983-12-15 ナシヨナル・リサ−チ・デイベロツプメント・コ−ポレイシヨン 殺虫剤
SI1731512T1 (sl) 2004-03-05 2015-01-30 Nissan Chemical Industries, Ltd. Z izoksazolinom substituirana benzamidna spojina in sredstvo za uravnavanje škodljivih organizmov
JP5051340B2 (ja) 2005-06-06 2012-10-17 日産化学工業株式会社 置換イソキサゾリン化合物及び有害生物防除剤
JP5293921B2 (ja) 2005-09-02 2013-09-18 日産化学工業株式会社 イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
JP2007106756A (ja) 2005-09-14 2007-04-26 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤
AU2006326449A1 (en) 2005-12-14 2007-06-21 E. I. Du Pont De Nemours And Company Isoxazolines for controlling invertebrate pests
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
EP1975149B1 (en) 2005-12-26 2012-02-15 Nissan Chemical Industries, Ltd. 1,3-bis(substituted phenyl)-3-hydroxypropan-1-one or 2-propen-1-one compound, and salt thereof
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
WO2007105814A1 (ja) 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. 置換イソキサゾリン化合物及び有害生物防除剤
WO2007125984A1 (ja) 2006-04-28 2007-11-08 Nihon Nohyaku Co., Ltd. イソキサゾリン誘導体及び有害生物防除剤並びにその使用方法
GB0614691D0 (en) 2006-07-24 2006-08-30 Syngenta Participations Ag Insecticidal compounds
JP2008044880A (ja) 2006-08-15 2008-02-28 Bayer Cropscience Ag 殺虫性イソオキサゾリン類
US8173638B2 (en) * 2006-11-21 2012-05-08 Boehringer Ingelheim International Gmbh Compounds which modulate the CB2 receptor
JP2008133242A (ja) 2006-11-29 2008-06-12 Nissan Chem Ind Ltd 置換フェニルリチウム化合物の製造方法
JP2008156347A (ja) 2006-11-29 2008-07-10 Nissan Chem Ind Ltd 新規アセトフェノン化合物およびアセトフェノン類の製造方法
JP2008239611A (ja) 2007-02-27 2008-10-09 Nissan Chem Ind Ltd イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
EP2151437A4 (en) 2007-03-07 2012-05-02 Nissan Chemical Ind Ltd ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT
BRPI0810196A2 (pt) 2007-04-10 2011-12-06 Bayer Cropscience Ag inseticidas de derivados de aril isoxazolina
WO2008130651A2 (en) 2007-04-20 2008-10-30 Dow Agrosciences Llc Diarylisoxazolines
TW200900398A (en) 2007-05-31 2009-01-01 Du Pont 3-cyano-4-triazolyl phenylisoxazoline invertebrate pest control agents
UA99460C2 (ru) 2007-06-01 2012-08-27 Басф Се Способ получения n-замещенных (3-дигалометил-1-метилпиразол-4-ил)карбоксамидов
US8623875B2 (en) 2007-06-13 2014-01-07 E.I. Du Pont De Nemours And Company Isoxazoline insecticides
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
EP2957284B1 (en) 2007-06-27 2018-01-17 E. I. du Pont de Nemours and Company Animal pest control method
EP2172462A4 (en) 2007-06-27 2010-12-15 Nissan Chemical Ind Ltd METHOD FOR PRODUCING A 3-HYDROXYPROPAN-1-ON COMPOUND, METHOD FOR PRODUCING A 2-PROPENE-1-ON COMPOUND, AND METHOD FOR PRODUCING AN ISOXAZOLINE COMPOUND
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
GB0720232D0 (en) * 2007-10-16 2007-11-28 Syngenta Participations Ag Insecticidal compounds
JP5365807B2 (ja) 2007-11-12 2013-12-11 日産化学工業株式会社 光学活性イソキサゾリン化合物の触媒的不斉合成方法
TWI455919B (zh) 2008-04-09 2014-10-11 Du Pont 製備３－三氟甲基查耳酮（ｃｈａｌｃｏｎｅ）之方法
TWI445705B (zh) 2008-05-20 2014-07-21 Astrazeneca Ab 經苯基及苯并二基取代之吲唑衍生物
WO2010003923A1 (en) 2008-07-09 2010-01-14 Basf Se Pestcidal active mixtures comprising isoxazoline compounds i
US8389738B2 (en) 2008-07-09 2013-03-05 Nissan Chemical Industries, Ltd. Production method of isoxazoline-substituted benzoic acid amide compound
JP5670328B2 (ja) 2008-07-09 2015-02-18 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ イソオキサゾリン化合物ｉｉを含む殺有害生物剤混合物
KR20110098848A (ko) 2008-12-23 2011-09-01 바스프 에스이 무척추동물 해충을 퇴치하기 위한 이민 화합물
MX2012014439A (es) 2010-06-23 2013-02-07 Basf Se Proceso para producir compuestos aromaticos de carbonilo e imina.
US9006447B2 (en) 2010-11-03 2015-04-14 Basf Se Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes
WO2012151512A2 (en) 2011-05-04 2012-11-08 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof

Also Published As

Publication number Publication date
WO2010125130A1 (en) 2010-11-04
JP2012525353A (ja) 2012-10-22
US20120059171A1 (en) 2012-03-08
DK2424862T3 (en) 2014-12-15
BRPI1006679A2 (pt) 2015-08-25
CN102414202B (zh) 2015-09-02
EP2424862B1 (en) 2014-10-08
IL215519A (en) 2015-11-30
ES2524970T3 (es) 2014-12-16
CN102414202A (zh) 2012-04-11
US8853410B2 (en) 2014-10-07
EP2424862A1 (en) 2012-03-07
BRPI1006679B1 (pt) 2016-12-20
IL215519A0 (en) 2011-12-29

Similar Documents

Publication Publication Date Title
MX2011011079A (es) Procedimiento para preparar compuestos de isoxazolina sustituidos y sus precursores.
MX2014006759A (es) Produccion de xilenos por metilacion de compuestos aromaticos.
PH12012501625A1 (en) Process for the preparation of isoxazoline derivatives
GEP20125512B (en) Process for synthesis of agomelatin
CN105473579A (zh) 布瑞哌唑、其关键中间体及其盐的制备方法
MX2012007043A (es) Proceso para el arranque de epoxidacion.
IN2012DN00775A (es)
MX2012000381A (es) Proceso para la fabricacion de precursores halogenados de alquenonas bajo condiciones especificas.
UA114601C2 (uk) Спосіб одержання ривароксабану та проміжних сполук, які одержано в даному способі
MX2012000379A (es) Proceso para la fabricacion de precursores halogenados de alquenonas en presencia de un solvente.
MX2013003123A (es) Proceso para preparar n-fenilhidroxilaminas sustituidas.
WO2010116140A8 (en) New process for preparing hydroxylamines and medicaments
NZ702935A (en) Process for making hydroxylated cyclopentylpyrimidine compounds
CL2008003059A1 (es) Metodo para preparar tigeciclina por formacion de un compuesto intermediario nitrado en presencia de una gas inerte y con aislacion de dicho intermediario
MX2010009950A (es) Metodo para purificar acido metacrilico.
IN2012DN00635A (es)
IL190040A0 (en) Method for the production of 5-fluoro-1,3-dialkyl-1h-pyrazol-4-carbonyl fluorides
IN2012DN05081A (es)
GEP20115344B (en) New process for synthesis of agomelatine
MX357509B (es) Sintesis de cleistantina a y derivados de la misma.
BR112012014347A2 (pt) processo de epoxidação e microestrutura
Zhang et al. Condensation reactions of aromatic aldehydes with 3-methyl-4, 5-dihydroisoxazol-5-one without solvent and catalyst
MX2014005869A (es) Proceso para preparar 2-alquenales 3-sustituidos, en particular prenal.
PH12012501251A1 (en) Method for producing tertiary amine
EA201270605A1 (ru) Превращение углеродсодержащего исходного сырья

Legal Events

Date Code Title Description
FG Grant or registration