[go: up one dir, main page]

MX2011008458A - Metodos para preparar agonistas y antagonistas del receptor s1p. - Google Patents

Metodos para preparar agonistas y antagonistas del receptor s1p.

Info

Publication number
MX2011008458A
MX2011008458A MX2011008458A MX2011008458A MX2011008458A MX 2011008458 A MX2011008458 A MX 2011008458A MX 2011008458 A MX2011008458 A MX 2011008458A MX 2011008458 A MX2011008458 A MX 2011008458A MX 2011008458 A MX2011008458 A MX 2011008458A
Authority
MX
Mexico
Prior art keywords
antagonists
methods
preparing
receptor agonists
agonists
Prior art date
Application number
MX2011008458A
Other languages
English (en)
Inventor
Su Yu
Anthony R Haight
Shashank Shekhar
Preston E Chmura
Vimal Kishore
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX2011008458A publication Critical patent/MX2011008458A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen métodos para hacer compuestos que son agonistas o antagonistas de uno o más de los receptores individuales de la familia del receptor S1P.
MX2011008458A 2009-02-10 2010-02-09 Metodos para preparar agonistas y antagonistas del receptor s1p. MX2011008458A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20730209P 2009-02-10 2009-02-10
PCT/US2010/023607 WO2010093616A1 (en) 2009-02-10 2010-02-09 Methods for preparing s1p receptor agonists and antagonists

Publications (1)

Publication Number Publication Date
MX2011008458A true MX2011008458A (es) 2011-09-01

Family

ID=42562034

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011008458A MX2011008458A (es) 2009-02-10 2010-02-09 Metodos para preparar agonistas y antagonistas del receptor s1p.

Country Status (7)

Country Link
US (1) US20110190540A1 (es)
EP (1) EP2395986A1 (es)
JP (1) JP2012517445A (es)
CN (1) CN102316862A (es)
CA (1) CA2750125A1 (es)
MX (1) MX2011008458A (es)
WO (1) WO2010093616A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI613182B (zh) 2013-02-21 2018-02-01 必治妥美雅史谷比公司 雙環化合物
AR101591A1 (es) 2014-08-20 2016-12-28 Bristol Myers Squibb Co Compuestos bicíclicos sustituidos
CN110128288B (zh) * 2018-02-02 2023-07-28 浙江九洲药业股份有限公司 一种氨基取代的环戊烷甲酸烷基酯衍生物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5428149A (en) * 1993-06-14 1995-06-27 Washington State University Research Foundation Method for palladium catalyzed carbon-carbon coulping and products
CA2479932A1 (en) * 2002-03-28 2003-10-09 Eli Lilly And Company Piperazine substituted aryl benzodiazepines and their use as dopamine receptor antagonists for the treatment of psychotic disorders
US8217027B2 (en) * 2006-12-21 2012-07-10 Abbott Laboratories Sphingosine-1-phosphate receptor agonist and antagonist compounds

Also Published As

Publication number Publication date
CN102316862A (zh) 2012-01-11
WO2010093616A1 (en) 2010-08-19
US20110190540A1 (en) 2011-08-04
JP2012517445A (ja) 2012-08-02
CA2750125A1 (en) 2010-08-19
EP2395986A1 (en) 2011-12-21

Similar Documents

Publication Publication Date Title
GB201017345D0 (en) Receptor antagonists
IN2012DN01241A (es)
IL214049A0 (en) Agonists and antagonists of the s1p5 receptor, and methods of uses thereof
MY160665A (en) Spiropiperidine compounds as orl-1 receptor antagonists
GB2470833A8 (en) Polycyclic antagonists of lysophosphatidic acid receptors.
MX2009006751A (es) Compuestos agonistas y antagonistas del receptor de esfingosina-1-fosfato.
SG179085A1 (en) Pi3 kinase inhibitors and uses thereof
EA201290355A1 (ru) Спиропиперидиновые соединения в качестве антагонистов рецептора orl-1
IL208895A0 (en) Nmda receptor antagonists for the treatment of neuropsychiatric disorders
IL219120A0 (en) Cgrp receptor antagonists
EP2350024A4 (en) IMPROVED METHOD FOR THE PRODUCTION OF ENDOTHELIN RECEPTOR ANTAGONISTS
AU2009226956A8 (en) Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HT antagonists
ZA201103419B (en) Arylcyclohexylethers of dihydrotetraazabenzoazulenes for use as vasopressin via receptor antagonists
IL198542A0 (en) 2-aminoquinolines as 5-ht(5a)receptor antagonists
MX2010010339A (es) Ciclohexildiaminas sustituidas.
IN2012DN03404A (es)
MX2011008458A (es) Metodos para preparar agonistas y antagonistas del receptor s1p.
ZA201003724B (en) Methods of identifying safe nmda receptor antagonists
EP2323989A4 (en) METHODS FOR PREPARING AGENTS FOR THE CENTRAL NERVOUS SYSTEM THAT ARE TRPV1 ANTAGONISTS
PH12012502300A1 (en) Nicotinic receptor non-competitive antagonists
IL207438A0 (en) 2-aminoquinolines as 5-ht5a receptor antagonists
IL222948A0 (en) Novel methods for the prepartion of p2x7r antagonists
PH12014500934A1 (en) Nicotinic receptor non-competitive modulators
UA51902U (ru) Применение антагониста рецепторов интерлейкина-1 (арил-1) в качестве способа фригопротекторного действия
UA108500C2 (ru) Неконкурентные антагонисты никотиновых рецепторов

Legal Events

Date Code Title Description
FA Abandonment or withdrawal