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MX2011001679A - Derivados de flavina. - Google Patents

Derivados de flavina.

Info

Publication number
MX2011001679A
MX2011001679A MX2011001679A MX2011001679A MX2011001679A MX 2011001679 A MX2011001679 A MX 2011001679A MX 2011001679 A MX2011001679 A MX 2011001679A MX 2011001679 A MX2011001679 A MX 2011001679A MX 2011001679 A MX2011001679 A MX 2011001679A
Authority
MX
Mexico
Prior art keywords
flavin derivatives
derivatives
flavin
infectives
compositions
Prior art date
Application number
MX2011001679A
Other languages
English (en)
Inventor
Kenneth F Blount
Brian R Dixon
Judd Berman
Philip D G Coish
David Osterman
Kaur Harpreet
Kevin Kells
Phil Wickens
Jeffrey Willson
Justin Wu
Jayhuk Myung
Bruce R Evans
Jeffrey A Leiby
Heinrich J Schostarez
Frank C Sciavolino
Dennis Underwood
Angelica Bello
David Moon
Vinh Pham
Tan Quach
Stephanie Avola
Nick Baboulas
Robert Gadwood
Original Assignee
Biorelix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biorelix Inc filed Critical Biorelix Inc
Publication of MX2011001679A publication Critical patent/MX2011001679A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a derivados novedosos de flavina y otros derivados de flavina, su uso y composiciones para usarse como ligandos ribo-reguladores (riboswitches (ARN que regula la expresión genética)) y/o anti-infectivos. La invención también proporciona un método para hacer derivados novedosos de flavina.
MX2011001679A 2008-08-11 2009-08-11 Derivados de flavina. MX2011001679A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18861908P 2008-08-11 2008-08-11
US21131409P 2009-03-25 2009-03-25
PCT/US2009/004576 WO2010019208A1 (en) 2008-08-11 2009-08-11 Flavin derivatives

Publications (1)

Publication Number Publication Date
MX2011001679A true MX2011001679A (es) 2011-12-16

Family

ID=41669135

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011001679A MX2011001679A (es) 2008-08-11 2009-08-11 Derivados de flavina.

Country Status (9)

Country Link
US (1) US20120077781A1 (es)
EP (1) EP2320734A4 (es)
JP (1) JP2011530595A (es)
KR (1) KR20110097754A (es)
CN (1) CN102176825A (es)
AU (1) AU2009282478A1 (es)
CA (1) CA2731946A1 (es)
MX (1) MX2011001679A (es)
WO (1) WO2010019208A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012532126A (ja) * 2009-06-30 2012-12-13 バイオレリックス・インコーポレイテッド フラビン誘導体
ES2730828T3 (es) 2010-02-01 2019-11-12 Rebiotix Inc Bacterioterapia para la colitis por Clostridium difficile
EP2531223A4 (en) * 2010-02-04 2013-06-26 Biorelix Inc NEW METHODS AND DEVICES
JP2013523811A (ja) * 2010-04-06 2013-06-17 バイオレリックス・インコーポレイテッド フラビン誘導体
WO2012109458A1 (en) * 2011-02-09 2012-08-16 Biorelix, Inc. Flavin derivatives
DE102011105653A1 (de) 2011-06-22 2012-12-27 TriOpto Tec GmbH 10H-Benzo[g]pteridin-2,4-dion-Derivate, Verfahren zur Herstellung und Verwendung derselben
DE102011105660A1 (de) 2011-06-22 2012-12-27 TriOpto Tec GmbH Verwendung von 10H-Benzo[g]pteridin-2,4-dion-Derivaten
DE102011105657A1 (de) 2011-06-22 2012-12-27 TriOpto Tec GmbH 10H-Benzo[g]pteridin-2,4-dion-Derivate, Verfahren zur Herstellung und Verwendung derselben
WO2013040412A2 (en) * 2011-09-14 2013-03-21 Biorelix, Inc. Methods for inhibiting bacteria growth
CN103184221B (zh) * 2011-12-30 2016-03-30 复旦大学 核开关aac及其在制备抗生素中的应用
HU230744B1 (hu) * 2012-11-30 2018-01-29 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Új eljárás travoprost előállítására
AR096135A1 (es) 2013-05-02 2015-12-09 Actelion Pharmaceuticals Ltd Derivados de la quinolona
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
HUE040211T2 (hu) 2013-06-05 2019-02-28 Rebiotix Inc Mikrobióta-helyreállítási terápia (MRT), készítmények és elõállítási eljárások
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US10383901B2 (en) 2013-06-05 2019-08-20 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
CN104496992B (zh) * 2014-12-29 2016-06-29 中国人民解放军国防科学技术大学 用于蓝光受体光致电子转移研究的模型化合物及其制备方法
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
ES2889902T3 (es) 2015-06-09 2022-01-14 Rebiotix Inc Métodos de fabricación de composiciones para terapia de restauración de la microbiota (TRM)
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10799539B2 (en) 2015-06-09 2020-10-13 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
JP2018131410A (ja) * 2017-02-15 2018-08-23 ヒノキ新薬株式会社 カスパーゼ−３阻害剤とその用途
CN110292799B (zh) * 2019-07-19 2021-06-15 绍兴市卓诚新材料有限公司 基于化学试验的防破损割伤的抽滤瓶结构
CN111675614B (zh) * 2020-07-14 2022-11-29 爱斯特（成都）生物制药股份有限公司 一种合成7-溴-2,2-二甲基庚酸乙酯的方法
CN115710272B (zh) * 2022-11-22 2024-03-26 上海交通大学 一种用于酶生物传感器的含乙烯基的异咯嗪衍生物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1394672A (en) * 1971-05-21 1975-05-21 Ici Ltd Radiation sensitive materials
US3920650A (en) * 1973-09-19 1975-11-18 Morton Norwich Products Inc Isoalloxazines
US5925354A (en) * 1995-11-30 1999-07-20 Michigan State University Riboflavin mutants as vaccines against Actinobacillus pleuropneumoniae
US6268120B1 (en) * 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US20030161871A1 (en) * 2001-12-19 2003-08-28 Geoffrey Hird Solubilized riboflavin

Also Published As

Publication number Publication date
US20120077781A1 (en) 2012-03-29
EP2320734A4 (en) 2012-08-15
AU2009282478A1 (en) 2010-02-18
KR20110097754A (ko) 2011-08-31
EP2320734A1 (en) 2011-05-18
WO2010019208A1 (en) 2010-02-18
JP2011530595A (ja) 2011-12-22
CN102176825A (zh) 2011-09-07
CA2731946A1 (en) 2010-02-18

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