MX2010014441A - Diaril ureas para tratar la insuficiencia cardiaca. - Google Patents
Diaril ureas para tratar la insuficiencia cardiaca.Info
- Publication number
- MX2010014441A MX2010014441A MX2010014441A MX2010014441A MX2010014441A MX 2010014441 A MX2010014441 A MX 2010014441A MX 2010014441 A MX2010014441 A MX 2010014441A MX 2010014441 A MX2010014441 A MX 2010014441A MX 2010014441 A MX2010014441 A MX 2010014441A
- Authority
- MX
- Mexico
- Prior art keywords
- heart failure
- treating heart
- diaryl ureas
- diaryl
- urea compound
- Prior art date
Links
- -1 Diaryl ureas Chemical class 0.000 title abstract 3
- 206010019280 Heart failures Diseases 0.000 title abstract 2
- 235000013877 carbamide Nutrition 0.000 title 1
- 239000004202 carbamide Substances 0.000 abstract 2
- MLDQJTXFUGDVEO-UHFFFAOYSA-N BAY-43-9006 Chemical compound C1=NC(C(=O)NC)=CC(OC=2C=CC(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 MLDQJTXFUGDVEO-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960003787 sorafenib Drugs 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a composiciones farmacéuticas y combinaciones para tratar, prevenir o gestionar la insuficiencia cardiaca y/o enfermedades relacionadas con la misma, que comprenden al menos un compuesto de diaril urea, opcionalmente combinado con al menos un agente terapéutico adicional. Las combinaciones útiles incluyen, por ejemplo, BAY 43-9006 como un compuesto de diaril urea.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08011471 | 2008-06-25 | ||
| PCT/EP2009/004390 WO2009156089A1 (en) | 2008-06-25 | 2009-06-18 | Diaryl ureas for treating heart failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010014441A true MX2010014441A (es) | 2011-01-21 |
Family
ID=41136709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010014441A MX2010014441A (es) | 2008-06-25 | 2009-06-18 | Diaril ureas para tratar la insuficiencia cardiaca. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20110263657A1 (es) |
| EP (1) | EP2293792A1 (es) |
| JP (1) | JP2011525506A (es) |
| KR (1) | KR20110031294A (es) |
| CN (1) | CN102076338A (es) |
| AU (1) | AU2009262599A1 (es) |
| BR (1) | BRPI0914636A2 (es) |
| CA (1) | CA2729050A1 (es) |
| IL (1) | IL209647A0 (es) |
| MX (1) | MX2010014441A (es) |
| RU (1) | RU2011102471A (es) |
| WO (1) | WO2009156089A1 (es) |
| ZA (1) | ZA201009063B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102718703B (zh) * | 2011-03-31 | 2016-09-14 | 中国医学科学院药物研究所 | Gk和ppar双重激动活性的含有二甲基的芳基脲类衍生物 |
| AU2012272898A1 (en) | 2011-06-24 | 2013-04-11 | Amgen Inc. | TRPM8 antagonists and their use in treatments |
| WO2012177893A2 (en) | 2011-06-24 | 2012-12-27 | Amgen Inc. | Trpm8 antagonists and their use in treatments |
| US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
| RU2646454C2 (ru) * | 2013-11-12 | 2018-03-05 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" | Способ моделирования алкогольной кардиомиопатии |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2288694T3 (es) * | 2003-05-20 | 2008-01-16 | Bayer Pharmaceuticals Corporation | Diaril ureas para enfermedades mediadas por el receptor del factor de crecimiento derivado de plaquetas. |
| KR101139557B1 (ko) * | 2003-07-23 | 2012-04-30 | 바이엘 파마슈티칼스 코포레이션 | 질환 및 상태의 치료 및 예방을 위한 플루오로 치환오메가-카르복시아릴 디페닐 우레아 |
| US20090197922A1 (en) * | 2006-01-24 | 2009-08-06 | The University Of Chicago | Compositions and methods for treating pulmonary hypertension |
| WO2009092442A1 (en) * | 2008-01-23 | 2009-07-30 | Universidad De Barcelona | Treatment of portal hypertension and related conditions by combined inhibition of the vegf and pdgf signalling pathways |
-
2009
- 2009-06-18 MX MX2010014441A patent/MX2010014441A/es not_active Application Discontinuation
- 2009-06-18 RU RU2011102471/15A patent/RU2011102471A/ru not_active Application Discontinuation
- 2009-06-18 KR KR1020107029143A patent/KR20110031294A/ko not_active Withdrawn
- 2009-06-18 CA CA2729050A patent/CA2729050A1/en not_active Abandoned
- 2009-06-18 BR BRPI0914636A patent/BRPI0914636A2/pt not_active IP Right Cessation
- 2009-06-18 US US13/001,145 patent/US20110263657A1/en not_active Abandoned
- 2009-06-18 CN CN2009801240616A patent/CN102076338A/zh active Pending
- 2009-06-18 AU AU2009262599A patent/AU2009262599A1/en not_active Abandoned
- 2009-06-18 WO PCT/EP2009/004390 patent/WO2009156089A1/en not_active Ceased
- 2009-06-18 EP EP09768938A patent/EP2293792A1/en not_active Withdrawn
- 2009-06-18 JP JP2011515168A patent/JP2011525506A/ja not_active Withdrawn
-
2010
- 2010-11-30 IL IL209647A patent/IL209647A0/en unknown
- 2010-12-17 ZA ZA2010/09063A patent/ZA201009063B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009262599A1 (en) | 2009-12-30 |
| WO2009156089A1 (en) | 2009-12-30 |
| IL209647A0 (en) | 2011-02-28 |
| BRPI0914636A2 (pt) | 2015-10-20 |
| RU2011102471A (ru) | 2012-07-27 |
| EP2293792A1 (en) | 2011-03-16 |
| ZA201009063B (en) | 2012-02-29 |
| CA2729050A1 (en) | 2009-12-30 |
| CN102076338A (zh) | 2011-05-25 |
| JP2011525506A (ja) | 2011-09-22 |
| KR20110031294A (ko) | 2011-03-25 |
| US20110263657A1 (en) | 2011-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |