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MX2010009951A - Metodos, composiciones y kits para tratar dolor y prurito. - Google Patents

Metodos, composiciones y kits para tratar dolor y prurito.

Info

Publication number
MX2010009951A
MX2010009951A MX2010009951A MX2010009951A MX2010009951A MX 2010009951 A MX2010009951 A MX 2010009951A MX 2010009951 A MX2010009951 A MX 2010009951A MX 2010009951 A MX2010009951 A MX 2010009951A MX 2010009951 A MX2010009951 A MX 2010009951A
Authority
MX
Mexico
Prior art keywords
kits
compositions
methods
pruritis
treating pain
Prior art date
Application number
MX2010009951A
Other languages
English (en)
Inventor
Bruce P Bean
Clifford J Woolf
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of MX2010009951A publication Critical patent/MX2010009951A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La invención presenta métodos, composiciones, y kits para inhibición selectiva de neuronas detectoras de dolor y comezón (nociceptores y pruriceptores) por moléculas de fármaco de pese moléculas pequeño, mientras que minimiza los efectos sobre neuronas no detectoras de dolor u otros tipos de células.
MX2010009951A 2008-03-11 2009-03-11 Metodos, composiciones y kits para tratar dolor y prurito. MX2010009951A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6901808P 2008-03-11 2008-03-11
PCT/US2009/001541 WO2009114139A2 (en) 2008-03-11 2009-03-11 Methods, compositions, and kits for treating pain and pruritis

Publications (1)

Publication Number Publication Date
MX2010009951A true MX2010009951A (es) 2011-09-01

Family

ID=41065720

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010009951A MX2010009951A (es) 2008-03-11 2009-03-11 Metodos, composiciones y kits para tratar dolor y prurito.

Country Status (11)

Country Link
US (1) US20110086818A1 (es)
EP (1) EP2271329A4 (es)
JP (1) JP2011513484A (es)
KR (1) KR20110044166A (es)
CN (1) CN102112121A (es)
AU (1) AU2009223739A1 (es)
BR (1) BRPI0909627A2 (es)
CA (1) CA2717042A1 (es)
IL (1) IL208027A0 (es)
MX (1) MX2010009951A (es)
WO (1) WO2009114139A2 (es)

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KR20140097446A (ko) 2006-11-20 2014-08-06 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 통증 및 소양증 치료용 방법, 조성물 및 키트
WO2010085589A2 (en) 2009-01-22 2010-07-29 G&H Brands Llc Desensitizing drug product
US20120172429A1 (en) * 2009-07-10 2012-07-05 Woolf Clifford J Permanently charged sodium and calcium channel blockers as anti- inflammatory agents
JP5832856B2 (ja) * 2010-12-15 2015-12-16 久光製薬株式会社 局所鎮痛作用増強剤及び局所鎮痛キット
AU2012219254B2 (en) 2011-02-18 2016-08-11 Libertas Bio, Inc. Aminoindane compounds and use thereof in treating pain
ES2596215T3 (es) 2011-10-24 2017-01-05 Asana Biosciences, Llc Ciclohexilaminas
US8779003B2 (en) 2011-12-29 2014-07-15 Mackay Memorial Hospital Method and composition for prolonging analgesic effect of local anesthetic
TWI603957B (zh) 2012-08-15 2017-11-01 阿沙納生物科學有限責任公司 胺基氫茚化合物用於治療膀胱過動症及間質性膀胱炎之用途
ES2704880T3 (es) 2013-02-08 2019-03-20 Gen Mills Inc Productos alimentarios reducidos en sodio
AU2015247815A1 (en) * 2014-04-14 2016-11-03 Flex Pharma, Inc. Ion channel activators and methods of use
JP6833811B2 (ja) * 2015-08-03 2021-02-24 プレジデント アンド フェローズ オブ ハーバード カレッジ 荷電イオンチャネル遮断薬及び使用方法
CN106214678B (zh) * 2016-07-26 2020-12-29 上海璃道医药科技有限公司 苯酮类药物的用途
US11253493B2 (en) 2017-01-23 2022-02-22 Cliff-Cartwright Corporation Compositions and methods affecting exercise performance
KR101877002B1 (ko) * 2017-03-06 2018-07-12 서울대학교 산학협력단 피라졸 유도체를 유효성분으로 함유하는 소양증의 예방 또는 치료용 약학적 조성물 및 이를 검출하기 위한 스크리닝 방법
KR101867779B1 (ko) * 2017-12-08 2018-06-19 서울대학교산학협력단 피라졸 유도체를 유효성분으로 함유하는 소양증의 예방 또는 치료용 약학적 조성물 및 이를 검출하기 위한 스크리닝 방법
WO2019144139A1 (en) * 2018-01-22 2019-07-25 Oregon State University Immunogenic compositions comprising mycobacterium bovis surface proteins and uses thereof
WO2019173394A1 (en) 2018-03-05 2019-09-12 Wylder Nation Foundation Compositions and methods for activating signaling through the cb1 cannabinoid receptor for treating and preventing diseases and disorders characterized by abnormal cellular accumulation of sphingolipids such as sphingomyelin
WO2020035555A2 (en) * 2018-08-15 2020-02-20 Pharmacyl Ab Substituted benzamides and their use in therapy
CN109498604A (zh) * 2018-12-24 2019-03-22 复旦大学 香叶醇新用途，预防和治疗非疾病引起的瘙痒症的配制品及方法
KR20210143791A (ko) 2019-03-11 2021-11-29 녹시온 테라퓨틱스 인코포레이티드 하전된 이온 채널 차단제 및 사용 방법
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN113924094A (zh) 2019-03-11 2022-01-11 诺西恩医疗公司 酯取代的离子通道阻滞剂及其使用方法
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP7678757B2 (ja) 2019-03-11 2025-05-16 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
WO2021091585A1 (en) 2019-11-06 2021-05-14 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US20230165812A1 (en) * 2020-02-27 2023-06-01 President And Fellows Of Harvard College Nociceptor neurons control cancer immunosurveillance
EP4114372A1 (en) * 2020-03-04 2023-01-11 Neucures, Inc. Use of qx314 to prevent sympathoexcitation associated with administration of trpv1 modulators
KR20230022830A (ko) 2020-03-11 2023-02-16 녹시온 테라퓨틱스 인코포레이티드 하전된 이온 채널 차단제 및 사용 방법
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN113509457B (zh) * 2020-09-07 2023-03-21 四川昇嘉科技有限公司 山椒素在制备治疗湿疹的药物中的用途
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

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US6413961B1 (en) * 1995-12-12 2002-07-02 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
CZ20022095A3 (cs) * 1999-12-15 2003-02-12 Ucb Farchim S. A. Cyklická kvarterní amoniová sloučenina pro použití při léčbě a/nebo prevenci kašle u teplokrevného živočicha a farmaceutický prostředek ji obsahující
CA2446060A1 (en) * 2001-05-07 2002-11-14 Corium International Compositions and delivery systems for administration of a local anesthetic agent
EP1610742B1 (en) * 2003-04-10 2015-01-21 Neurogesx, Inc. Uses and compositions for administration of capsaicin
ES2223277B1 (es) * 2003-06-19 2006-03-01 Fernando Bouffard Fita Composicion anestesica para administracion topica.
US8658201B2 (en) * 2004-01-30 2014-02-25 Corium International, Inc. Rapidly dissolving film for delivery of an active agent
WO2005117981A1 (en) * 2004-06-02 2005-12-15 Sri International Formulations comprising a capsaicinoid a local anesthetic and/or an antipruritic agent for the treatment of pain
KR20140097446A (ko) * 2006-11-20 2014-08-06 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 통증 및 소양증 치료용 방법, 조성물 및 키트

Also Published As

Publication number Publication date
EP2271329A2 (en) 2011-01-12
US20110086818A1 (en) 2011-04-14
CA2717042A1 (en) 2009-09-17
BRPI0909627A2 (pt) 2018-04-10
IL208027A0 (en) 2010-12-30
JP2011513484A (ja) 2011-04-28
KR20110044166A (ko) 2011-04-28
CN102112121A (zh) 2011-06-29
EP2271329A4 (en) 2013-01-09
AU2009223739A1 (en) 2009-09-17
WO2009114139A3 (en) 2009-12-23
WO2009114139A2 (en) 2009-09-17

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Legal Events

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