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MX2010009814A - Compuestos con vitamina d y metodos para reducir la hipertension ocular. - Google Patents

Compuestos con vitamina d y metodos para reducir la hipertension ocular.

Info

Publication number
MX2010009814A
MX2010009814A MX2010009814A MX2010009814A MX2010009814A MX 2010009814 A MX2010009814 A MX 2010009814A MX 2010009814 A MX2010009814 A MX 2010009814A MX 2010009814 A MX2010009814 A MX 2010009814A MX 2010009814 A MX2010009814 A MX 2010009814A
Authority
MX
Mexico
Prior art keywords
compounds
methods
oht
vitamin
ocular hypertension
Prior art date
Application number
MX2010009814A
Other languages
English (en)
Inventor
Hector F Deluca
Galina D Kutuzova
Paul L Kaufman
B'ann True Gabelt
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of MX2010009814A publication Critical patent/MX2010009814A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a compuestos y métodos para reducir la presión intraocular y tratar hipertensión ocular en un sujeto.
MX2010009814A 2008-03-10 2009-03-10 Compuestos con vitamina d y metodos para reducir la hipertension ocular. MX2010009814A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3519208P 2008-03-10 2008-03-10
PCT/US2009/036679 WO2009114540A2 (en) 2008-03-10 2009-03-10 Vitamin d compounds and methods for reducing ocular hypertension (oht)

Publications (1)

Publication Number Publication Date
MX2010009814A true MX2010009814A (es) 2010-10-15

Family

ID=41065797

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010009814A MX2010009814A (es) 2008-03-10 2009-03-10 Compuestos con vitamina d y metodos para reducir la hipertension ocular.

Country Status (6)

Country Link
US (1) US9452177B2 (es)
EP (1) EP2265266B1 (es)
JP (1) JP5753386B2 (es)
CA (1) CA2717362A1 (es)
MX (1) MX2010009814A (es)
WO (1) WO2009114540A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8664206B2 (en) 2010-03-23 2014-03-04 Wisconsin Alumni Research Foundation Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3
EP2556054B1 (en) * 2010-03-23 2017-09-27 Wisconsin Alumni Research Foundation Diastereomers of 2-methylene-19-nor-22-methyl-1alpha,25-dihydroxyvitamin d3
JP5770261B2 (ja) * 2010-03-23 2015-08-26 ウイスコンシン アラムニ リサーチ ファンデーション （２０Ｓ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ジヒドロキシビタミンＤ３および（２０Ｒ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ヒドロキシビタミンＤ３
AU2016303346B2 (en) * 2015-08-05 2021-01-28 Wisconsin Alumni Research Foundation Synthesis and biological activity of 2-methylene analogs of calcitriol and related compounds

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW422696B (en) * 1995-03-20 2001-02-21 Katsuhiko Mukai Ophthalmic composition containing active vitamin D
JPH10158171A (ja) * 1996-12-02 1998-06-16 Kita:Kk ビタミンｄ化合物を配合した眼内投与剤
EP0998925A4 (en) * 1997-05-26 2003-02-26 New Vision Co Ltd TOPICAL ADMINISTRATION COMPOSITIONS CONTAINING VITAMINS D AND VITAMINS K
FR2801307B1 (fr) 1999-11-24 2002-12-06 Galderma Res & Dev Analogues de la vitamine d
CA2409759A1 (en) 2000-05-09 2001-11-15 Children's Medical Center Corporation Method and composition for the treatment of angiogenesis
AU2003233731A1 (en) 2002-06-06 2003-12-22 Xavier Billot 1,5-disubstituted imidazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of eye and bone diseases
WO2005027931A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and an ep2 or ep4 selective agonist
ATE455749T1 (de) 2003-10-14 2010-02-15 X Ceptor Therapeutics Inc Verbindungen mit verbrückten ringen als pharmazeutische mittel
US20070099879A1 (en) * 2005-10-31 2007-05-03 Wisconsin Alumni Research Foundation (Warf) Method of using calcitriol for treating intraocular diseases associated with angiogenesis
EP2010483A2 (en) 2006-04-05 2009-01-07 Wisconsin Alumni Research Foundation 1.alpha.-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin d compounds and methods of making and use thereof

Also Published As

Publication number Publication date
JP2011513494A (ja) 2011-04-28
WO2009114540A3 (en) 2010-03-25
WO2009114540A2 (en) 2009-09-17
US9452177B2 (en) 2016-09-27
WO2009114540A9 (en) 2010-02-04
EP2265266A2 (en) 2010-12-29
EP2265266B1 (en) 2016-06-15
EP2265266A4 (en) 2011-09-07
AU2009223668A1 (en) 2009-09-17
CA2717362A1 (en) 2009-09-17
US20110059926A1 (en) 2011-03-10
JP5753386B2 (ja) 2015-07-22

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal