MX2010009578A - Metodos para incrementar el espesor epidermico de la piel mediante la administracion topica de un compuesto de vitamina d que contiene 19-nor. - Google Patents
Metodos para incrementar el espesor epidermico de la piel mediante la administracion topica de un compuesto de vitamina d que contiene 19-nor.Info
- Publication number
- MX2010009578A MX2010009578A MX2010009578A MX2010009578A MX2010009578A MX 2010009578 A MX2010009578 A MX 2010009578A MX 2010009578 A MX2010009578 A MX 2010009578A MX 2010009578 A MX2010009578 A MX 2010009578A MX 2010009578 A MX2010009578 A MX 2010009578A
- Authority
- MX
- Mexico
- Prior art keywords
- methylene
- hydroxy
- vitamin
- methods
- dihydroxyvitamin
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229940046008 vitamin d Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 238000011200 topical administration Methods 0.000 title 1
- 229960005084 calcitriol Drugs 0.000 abstract 3
- 239000011647 vitamin D3 Substances 0.000 abstract 2
- 229940021056 vitamin d3 Drugs 0.000 abstract 2
- 229930003316 Vitamin D Natural products 0.000 abstract 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 210000002615 epidermis Anatomy 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 abstract 1
- 239000006208 topical dosage form Substances 0.000 abstract 1
- 239000012049 topical pharmaceutical composition Substances 0.000 abstract 1
- 239000011710 vitamin D Substances 0.000 abstract 1
- 235000019166 vitamin D Nutrition 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Métodos para incrementar el espesor de la capa epidérmica en la piel de un humano, que comprenden administrar tópicamente una dosis terapéuticamente efectiva de un ingrediente farmacéutico, activo que comprende un análogo de vitamina D que incluye 2-metilen-19-nor-20(S)-1a-hidroxi-bishomopregnacalciferol, 19-nor-26,27-dimetilen-20(S)-2-metilen-1a,25-dihidroxivitamina D3, 2-metilen-19-nor(24R)-1a, 25-dihidroxivitamia D2, 2-metilen-1a, 25-dihidroxi-(17E)-17(20)-deshidro-19-nor-vitamina D3, 2-metilen-(20R,25S)-19,26-dinor-1a,25-dihidroxivitamina D3, 2-metilen-18,19-dinor-(20S)-1a,25-dihidroxivitamina D3 2-metilen-19-nor-1a-hidroxipregnacalciferol, 1a-hidroxi-2-metilen- 19-nor-homopregnacalciferol, (20R)-1a-hidroxi2-metilen-19-nor-bish omopregnacalciferol, 2-metilen-(20S)-19-nor-1a-hidroxitrishomopreg nacalciferol, 2-metilen-(20R)-23,23-difluoro-1a-hidroxi-19-nor-bis homopregnacalciferol, 2-metilen-(20S)-23,23-difluoro-1a-hidroxi-19 -nor-bishomopregnancalciferol, 2-(3´hidroxipropil-1´ ,2´-ideno)-19,23,24-trinor-(20S)-1a-hidroxivitamina D3, o análogo de 13,13 -dimetil-des-C,D de (20S)-2-metilen-1a, 25-dihidroxi-19-nor-vitamina D3, y formulaciones tópicas farmacéuticas y formas de dosis tópicas de las mismas que usan un vehículo portador farmacéuticamente adecuado.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3440108P | 2008-03-06 | 2008-03-06 | |
| PCT/US2009/036323 WO2009111695A1 (en) | 2008-03-06 | 2009-03-06 | Methods of increasing epidermal skin thickness by topical administration of a 19-nor containing vitamin d compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010009578A true MX2010009578A (es) | 2010-09-24 |
Family
ID=40750898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010009578A MX2010009578A (es) | 2008-03-06 | 2009-03-06 | Metodos para incrementar el espesor epidermico de la piel mediante la administracion topica de un compuesto de vitamina d que contiene 19-nor. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8143238B2 (es) |
| EP (1) | EP2262507A1 (es) |
| JP (1) | JP2011513428A (es) |
| AU (1) | AU2009221717A1 (es) |
| CA (1) | CA2715811A1 (es) |
| MX (1) | MX2010009578A (es) |
| WO (1) | WO2009111695A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101880032B1 (ko) * | 2009-08-14 | 2018-07-20 | 베르그 엘엘씨 | 탈모증 치료용 비타민 ｄ3 및 이의 유사체들 |
| US8664206B2 (en) | 2010-03-23 | 2014-03-04 | Wisconsin Alumni Research Foundation | Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3 |
| EP2556054B1 (en) * | 2010-03-23 | 2017-09-27 | Wisconsin Alumni Research Foundation | Diastereomers of 2-methylene-19-nor-22-methyl-1alpha,25-dihydroxyvitamin d3 |
| JP5770261B2 (ja) * | 2010-03-23 | 2015-08-26 | ウイスコンシン アラムニ リサーチ ファンデーション | （２０Ｓ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ジヒドロキシビタミンＤ３および（２０Ｒ）−２−メチレン−１９−ノル−２２−ジメチル−１α，２５−ヒドロキシビタミンＤ３ |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6392071B1 (en) * | 1997-03-17 | 2002-05-21 | Wisconsin Alumni: Research Foundation | 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds |
| ES2227215T3 (es) | 2000-09-08 | 2005-04-01 | Wisconsin Alumni Research Foundation | 1 alfa-hidroxi.2.metilen-19-nor-homopregnacalciferol y sus aplicaciones terapeuticas. |
| PT1453798E (pt) | 2001-12-13 | 2009-01-23 | Wisconsin Alumni Res Found | (20s)-1alfa-hidroxi-2-metileno-19-nor-bishomopregnacalciferol e suas utilizações |
| US6566352B1 (en) * | 2002-02-18 | 2003-05-20 | Wisconsin Alumni Research Foudation | 1 α-hydroxy-2-methylene-19-nor-pregnacalciferol and its uses |
| WO2005051323A2 (en) * | 2003-11-25 | 2005-06-09 | Wisconsin Alumni Research Foundation | Vitamin d analogs for obesity prevention and treatment |
| US8404667B2 (en) | 2006-12-29 | 2013-03-26 | Wisconsin Alumni Research Foundation | Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog |
| CA2588038A1 (en) | 2004-11-22 | 2006-06-01 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-(20r)-1-.alpha.-hydroxy-bishomopregnacalciferol |
| EP1828115A4 (en) * | 2004-11-22 | 2010-05-05 | Wisconsin Alumni Res Found | 2-METHYLENE-19-NOR (20S) -1ALPHA-HYDROXYTRISHOMOPREGNACALCIFEROL |
| WO2006057917A2 (en) | 2004-11-23 | 2006-06-01 | Fmc Corporation | Hemipteran 5ht1 receptor |
| EP1848442B1 (en) | 2005-02-11 | 2012-04-25 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-(20s-24epi)-1alpha,25-dihydroxyvitamine-d2 |
| US7528122B2 (en) * | 2006-02-02 | 2009-05-05 | Wisconsin Alumni Research Foundation | Vitamin D analog—NEL, methods and uses thereof |
| EP2010483A2 (en) | 2006-04-05 | 2009-01-07 | Wisconsin Alumni Research Foundation | 1.alpha.-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin d compounds and methods of making and use thereof |
-
2009
- 2009-03-06 US US12/399,070 patent/US8143238B2/en not_active Expired - Fee Related
- 2009-03-06 AU AU2009221717A patent/AU2009221717A1/en not_active Abandoned
- 2009-03-06 JP JP2010549906A patent/JP2011513428A/ja not_active Withdrawn
- 2009-03-06 CA CA2715811A patent/CA2715811A1/en not_active Abandoned
- 2009-03-06 EP EP09717269A patent/EP2262507A1/en not_active Withdrawn
- 2009-03-06 WO PCT/US2009/036323 patent/WO2009111695A1/en not_active Ceased
- 2009-03-06 MX MX2010009578A patent/MX2010009578A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009221717A1 (en) | 2009-09-11 |
| EP2262507A1 (en) | 2010-12-22 |
| US8143238B2 (en) | 2012-03-27 |
| WO2009111695A8 (en) | 2009-10-15 |
| CA2715811A1 (en) | 2009-09-11 |
| JP2011513428A (ja) | 2011-04-28 |
| US20090227545A1 (en) | 2009-09-10 |
| WO2009111695A1 (en) | 2009-09-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US9901587B2 (en) | Topical film delivery system | |
| Mercadante | Pharmacotherapy for breakthrough cancer pain | |
| WO2008157103A3 (en) | Modified release solid or semi-solid dosage forms | |
| WO2004105694A3 (en) | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs | |
| ATE509616T1 (de) | Topische pharmazeutische und/oder cosmetische dosierungssysteme | |
| WO2005065319A3 (en) | Generally linear effervescent oral fentanyl dosage form and methods of administering | |
| WO2007134292A3 (en) | Treprostinil administration using a metered dose inhaler | |
| JP2010525050A5 (es) | ||
| WO2003039436A3 (es) | Composiciones farmaceuticas que contienen oxibutinina | |
| AR062320A1 (es) | Formulaciones de flibanserina y metodo para fabricarlas | |
| WO2008064192A3 (en) | Modified release analgesic suspensions | |
| MX344787B (es) | Composiciones que contienen berberina o analogos de la misma para tratar rosacea o trastornos de la piel relacionados con enrojecimiento de la cara. | |
| WO2007012019A3 (en) | Medicaments containing famotidine and ibuprofen and administration of same | |
| NZ605469A (en) | Nalbuphine-based formulations and uses thereof | |
| EP2591769A3 (en) | Compounds, compositions, kits and methods of use to topically treat acne and other skin conditions by administering a 19-nor containing vitamin D analog. | |
| BRPI0510760A (pt) | método para administrar a um paciente uma composição, composição tópica, e, emplastro | |
| WO2005081742A3 (en) | Testosterone oral dosage formulations and associated methods | |
| MX2010009578A (es) | Metodos para incrementar el espesor epidermico de la piel mediante la administracion topica de un compuesto de vitamina d que contiene 19-nor. | |
| Hu et al. | Percutaneous absorption and brain distribution facilitation of borneol on tetramethylpyrazine in a microemulsion-based transdermal therapeutic system | |
| WO2004073622A3 (en) | Novel therapeutic method and compositions for topical administration | |
| ES2149279T3 (es) | Sistema terapeutico para el tratamiento de la psoriasis. | |
| MX341660B (es) | Agonista del receptor de ghrelina para el tratamiento de caquexia. | |
| US20250339409A1 (en) | Uses of pan bet inhibitors | |
| CA2519789A1 (en) | Aplidine for multiple myeloma treatment | |
| AR048318A1 (es) | Formulaciones de matriz orales que comprenden licarbazepina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |