MX2010008285A - Forma galenica para la administracion de triptanos por via trans-mucosa bucal. - Google Patents
Forma galenica para la administracion de triptanos por via trans-mucosa bucal.Info
- Publication number
- MX2010008285A MX2010008285A MX2010008285A MX2010008285A MX2010008285A MX 2010008285 A MX2010008285 A MX 2010008285A MX 2010008285 A MX2010008285 A MX 2010008285A MX 2010008285 A MX2010008285 A MX 2010008285A MX 2010008285 A MX2010008285 A MX 2010008285A
- Authority
- MX
- Mexico
- Prior art keywords
- active ingredient
- triptans
- transmucosal delivery
- oral transmucosal
- galenic form
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 210000003300 oropharynx Anatomy 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
El objeto de la invención es una forma galénica para la administración por vía trans-mucosa bucal de al menos un principio activo de la familia de los triptanos, que comprenda al menos: dicho principio activo bajo la forma base y bajo la forma de sal, y; una solución hidro-alcohólica que titule al menos 15 grados de alcohol, dicho principio activo que esté presente en estado de disolución estable y completa en la solución hidro-alcohólica, de manera de permitir una absorción rápida de dicho principio activo a través de las mucosas de la cavidad bucal y/o de la orofaringe. La invención concierne también a un procedimiento de obtención de esta formulación galénica así como a su utilización.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0850571A FR2926721B1 (fr) | 2008-01-30 | 2008-01-30 | Forme galenique pour l'adminsitration par voie trans-muqueuse de triptans |
| PCT/FR2009/050134 WO2009095621A1 (fr) | 2008-01-30 | 2009-01-29 | Forme galenique pour l'administration de triptans par voie trans-muqueuse buccale |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010008285A true MX2010008285A (es) | 2010-10-04 |
Family
ID=39766922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010008285A MX2010008285A (es) | 2008-01-30 | 2009-01-29 | Forma galenica para la administracion de triptanos por via trans-mucosa bucal. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9801815B2 (es) |
| EP (1) | EP2252263B1 (es) |
| JP (1) | JP5435659B2 (es) |
| CN (1) | CN101983052B (es) |
| AT (1) | ATE516015T1 (es) |
| BR (1) | BRPI0907203A2 (es) |
| CA (1) | CA2713163C (es) |
| DK (1) | DK2252263T3 (es) |
| ES (1) | ES2369747T3 (es) |
| FR (1) | FR2926721B1 (es) |
| MX (1) | MX2010008285A (es) |
| PL (1) | PL2252263T3 (es) |
| PT (1) | PT2252263E (es) |
| RU (1) | RU2492852C2 (es) |
| WO (1) | WO2009095621A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3000896B1 (fr) * | 2013-01-14 | 2016-08-26 | Philippe Perovitch | Forme galenique pour l'administration de principe(s) actif(s) permettant l'induction acceleree du sommeil et/ou le traitement des troubles du sommeil |
| FR3031668A1 (fr) | 2015-01-20 | 2016-07-22 | Philippe Perovitch | Dispositif d'administration d'un principe actif par voie per-muqueuse buccale. |
| FR3053244A1 (fr) | 2016-07-01 | 2018-01-05 | Philippe Perovitch | Dispositif d'administration d'au moins un principe actif par voie per-muqueuse buccale. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4888354A (en) * | 1987-12-21 | 1989-12-19 | Theratech, Inc. | Skin penetration enhancement using free base and acid addition salt combinations of active agents |
| IT1291895B1 (it) * | 1997-04-24 | 1999-01-21 | Errekappa Euroterapici S P A | Preparazione farmaceutica fluida a base di nimesulide per uso orale e rinofaringeo |
| CN1145486C (zh) * | 1997-07-03 | 2004-04-14 | 美国辉瑞有限公司 | 含eletriptan半硫酸盐和咖啡因的药用组合物 |
| US20040136913A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing sumatriptan |
| GB9816556D0 (en) * | 1998-07-30 | 1998-09-30 | Pfizer Ltd | Therapy |
| US20070166336A1 (en) * | 2005-12-13 | 2007-07-19 | David Delmarre | Stable and palatable oral liquid sumatriptan compositions |
| FR2906140B1 (fr) * | 2006-09-22 | 2008-12-05 | Philippe Perovitch | Forme galenique pour l'administration par voie trans-muqueuse de principes actifs |
-
2008
- 2008-01-30 FR FR0850571A patent/FR2926721B1/fr not_active Expired - Fee Related
-
2009
- 2009-01-29 PL PL09706112T patent/PL2252263T3/pl unknown
- 2009-01-29 CN CN2009801038906A patent/CN101983052B/zh not_active Expired - Fee Related
- 2009-01-29 JP JP2010544764A patent/JP5435659B2/ja not_active Expired - Fee Related
- 2009-01-29 BR BRPI0907203-9A patent/BRPI0907203A2/pt not_active Application Discontinuation
- 2009-01-29 CA CA2713163A patent/CA2713163C/fr not_active Expired - Fee Related
- 2009-01-29 US US12/863,633 patent/US9801815B2/en not_active Expired - Fee Related
- 2009-01-29 ES ES09706112T patent/ES2369747T3/es active Active
- 2009-01-29 RU RU2010136277/15A patent/RU2492852C2/ru active
- 2009-01-29 AT AT09706112T patent/ATE516015T1/de active
- 2009-01-29 PT PT09706112T patent/PT2252263E/pt unknown
- 2009-01-29 DK DK09706112.1T patent/DK2252263T3/da active
- 2009-01-29 MX MX2010008285A patent/MX2010008285A/es active IP Right Grant
- 2009-01-29 WO PCT/FR2009/050134 patent/WO2009095621A1/fr not_active Ceased
- 2009-01-29 EP EP09706112A patent/EP2252263B1/fr not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| RU2010136277A (ru) | 2012-03-10 |
| US20100298401A1 (en) | 2010-11-25 |
| FR2926721A1 (fr) | 2009-07-31 |
| FR2926721B1 (fr) | 2011-07-22 |
| EP2252263A1 (fr) | 2010-11-24 |
| BRPI0907203A2 (pt) | 2015-07-14 |
| CN101983052A (zh) | 2011-03-02 |
| PT2252263E (pt) | 2011-10-19 |
| CA2713163A1 (fr) | 2009-08-06 |
| ATE516015T1 (de) | 2011-07-15 |
| WO2009095621A1 (fr) | 2009-08-06 |
| EP2252263B1 (fr) | 2011-07-13 |
| ES2369747T3 (es) | 2011-12-05 |
| CN101983052B (zh) | 2013-03-20 |
| JP5435659B2 (ja) | 2014-03-05 |
| DK2252263T3 (da) | 2011-10-31 |
| US9801815B2 (en) | 2017-10-31 |
| JP2011510962A (ja) | 2011-04-07 |
| RU2492852C2 (ru) | 2013-09-20 |
| CA2713163C (fr) | 2016-11-08 |
| PL2252263T3 (pl) | 2011-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |