[go: up one dir, main page]

MX2010005579A - Aparato y metodo para deteccion de un analito en una muestra. - Google Patents

Aparato y metodo para deteccion de un analito en una muestra.

Info

Publication number
MX2010005579A
MX2010005579A MX2010005579A MX2010005579A MX2010005579A MX 2010005579 A MX2010005579 A MX 2010005579A MX 2010005579 A MX2010005579 A MX 2010005579A MX 2010005579 A MX2010005579 A MX 2010005579A MX 2010005579 A MX2010005579 A MX 2010005579A
Authority
MX
Mexico
Prior art keywords
analyte
sample
detection
measurement channel
microstructure
Prior art date
Application number
MX2010005579A
Other languages
English (en)
Inventor
Emmanuel Delamarche
Daniel J Solis
Original Assignee
Ibm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ibm filed Critical Ibm
Publication of MX2010005579A publication Critical patent/MX2010005579A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5029—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/11—Orthomyxoviridae, e.g. influenza virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Se proporciona un aparato para la detección de un analito en una muestra. El aparato comprende al menos un primer canal de medición (2a) que comprende un reactivo de detección (3) que corresponde al analito (4) a detectar, y al menos una micro estructura (5) asociada con el primer canal de medición (2a) . Cuando el aparato (1) está en uso, la muestra se introduce en el primer canal de medición (2a) y propaga mediante el primer canal de medición (2a) hacia la micro estructura (5), de manera tal que el analito (4) si está presente en la muestra, interactúa con el reactivo de detección (3) para formar un producto en red (6), y la micro estructura (5) se configura para filtrar el producto en red (6).
MX2010005579A 2007-11-29 2008-10-30 Aparato y metodo para deteccion de un analito en una muestra. MX2010005579A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07121895 2007-11-29
PCT/IB2008/054525 WO2009069023A2 (en) 2007-11-29 2008-10-30 Apparatus and method for detection of an analyte in a sample

Publications (1)

Publication Number Publication Date
MX2010005579A true MX2010005579A (es) 2010-06-01

Family

ID=40380091

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005579A MX2010005579A (es) 2007-11-29 2008-10-30 Aparato y metodo para deteccion de un analito en una muestra.

Country Status (8)

Country Link
US (3) US9012136B2 (es)
EP (1) EP2234723A2 (es)
JP (1) JP5357174B2 (es)
KR (1) KR101253391B1 (es)
CN (1) CN101896273B (es)
CA (1) CA2701069C (es)
MX (1) MX2010005579A (es)
WO (1) WO2009069023A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101253391B1 (ko) 2007-11-29 2013-04-11 인터내셔널 비지네스 머신즈 코포레이션 표본 내 분석물을 검출하기 위한 장치 및 방법
EP2512647A2 (en) * 2009-12-18 2012-10-24 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge
ES2765865T3 (es) 2015-01-14 2020-06-11 Bio Rad Laboratories Sistemas y procedimientos de análisis de sangre
WO2016118757A1 (en) 2015-01-23 2016-07-28 Bio-Rad Laboratories, Inc. Immunoblotting systems and methods
JP7302148B2 (ja) * 2018-08-03 2023-07-04 株式会社ニコン 流体デバイスキットおよび流体デバイス

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE174813T1 (de) 1992-05-01 1999-01-15 Univ Pennsylvania Polynukleotide amplifikationsanalyse mit einer mikrofabrizierten vorrichtung
US6953676B1 (en) * 1992-05-01 2005-10-11 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
CA2152756A1 (en) 1994-06-28 1995-12-29 Tadakazu Yamauchi Method and device for specific binding assay
US5707799A (en) 1994-09-30 1998-01-13 Abbott Laboratories Devices and methods utilizing arrays of structures for analyte capture
US7799521B2 (en) * 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
KR100675698B1 (ko) * 1999-08-06 2007-02-01 써모 바이오스타, 인크. 완전한 샘플 처리 능력을 포함하는 자동화된 진료 검출 시스템
SE0001768D0 (sv) * 2000-05-12 2000-05-12 Helen Andersson Mikrofluidisk flödescell för manipulering av partiklar
US7052831B2 (en) * 2000-09-29 2006-05-30 Becton Dickinson And Company Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
US20030045001A1 (en) 2001-08-29 2003-03-06 Deborah Burgess Immunochromatographic test strip with arcuate sample application zone for ease-of-use in the field
US20040259076A1 (en) * 2003-06-23 2004-12-23 Accella Scientific, Inc. Nano and micro-technology virus detection method and device
JP2007519896A (ja) * 2003-12-17 2007-07-19 インバネス、メディカル、スウィッツァランド、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツング システム
GB0329220D0 (en) * 2003-12-17 2004-01-21 Inverness Medical Switzerland System
DE102004027422A1 (de) * 2004-06-04 2005-12-29 Boehringer Ingelheim Microparts Gmbh Vorrichtung zur Aufnahme von Blut und Abtrennung von Blutbestandteilen
US8389209B2 (en) * 2005-12-08 2013-03-05 Coris Bioconcept Test device for rapid diagnostics
US7695687B2 (en) * 2006-06-30 2010-04-13 International Business Machines Corporation Capillary system for controlling the flow rate of fluids
KR100764022B1 (ko) * 2006-10-02 2007-10-08 포항공과대학교 산학협력단 응집반응을 기초로 하는 혈액형 진단용 미세 유체 바이오칩
US7718420B2 (en) * 2006-10-10 2010-05-18 Postech Academy-Industry Foundation Microfluidic biochip for blood typing based on agglutination reaction
KR101253391B1 (ko) * 2007-11-29 2013-04-11 인터내셔널 비지네스 머신즈 코포레이션 표본 내 분석물을 검출하기 위한 장치 및 방법

Also Published As

Publication number Publication date
CN101896273B (zh) 2014-10-01
WO2009069023A2 (en) 2009-06-04
US9012136B2 (en) 2015-04-21
CA2701069C (en) 2016-03-15
US20120214153A1 (en) 2012-08-23
KR101253391B1 (ko) 2013-04-11
JP2011505555A (ja) 2011-02-24
US20150198596A1 (en) 2015-07-16
US20110117539A1 (en) 2011-05-19
US9005887B2 (en) 2015-04-14
US9594082B2 (en) 2017-03-14
WO2009069023A3 (en) 2009-07-16
EP2234723A2 (en) 2010-10-06
CA2701069A1 (en) 2009-06-04
CN101896273A (zh) 2010-11-24
JP5357174B2 (ja) 2013-12-04
KR20100081320A (ko) 2010-07-14

Similar Documents

Publication Publication Date Title
WO2010011798A3 (en) Method and system for detection and/or characterization of a biological particle in a sample
WO2010009411A3 (en) Hydrocarbon determination in presence of electron and chemical ionization
MY163654A (en) Apparatus and method for analysis of a fluid sample
GB2468043B (en) Methods for determining the permeability and diffusivity of a porous solid
WO2007120996A3 (en) Method and apparatus for compact spectrometer for detecting hazardous agents
WO2009121032A3 (en) Sample preparation devices and methods for processing analytes
WO2008090330A8 (en) Detecting objects
WO2009048673A3 (en) Stochastic confinement to detect, manipulate, and utilize molecules and organisms
WO2006088792A3 (en) Method and apparatus for detection of multiple analytes
EP1962085A3 (en) Apparatus for emitting and detecting beams of light
WO2008153987A3 (en) Methods for determining hepatocellular carcinoma subtype and detecting hepatic cancer stem cells
WO2010080702A3 (en) Gene expression profiling for the identification, monitoring, and treatment of prostate cancer
EP2863218A3 (en) System and method for measuring hydrogen content in a sample
WO2002010708A3 (en) Hygiene monitoring
WO2009003441A3 (de) Verfahren zur untersuchung der wirkung eines gasförmigen mediums auf ein biologisches prüfsystem unter verwendung eines extrazellulären metabolisierungssystems sowie vorrichtung zur durchführung des verfahrens
TW200712487A (en) Apparatus and method for detecting an analyte
MX2010005017A (es) Metodos y aparatos para determinar una concentracion de nitrogeno en un fluido de fondo de pozo.
WO2009105212A3 (en) Detection of polyomavirus
MX2010005579A (es) Aparato y metodo para deteccion de un analito en una muestra.
WO2011006913A8 (de) Optimiertes lanzettenband
IL212082A0 (en) Device, kit and method for pulsing biological samples with an agent and stabilising the sample so pulsed
PL2005164T3 (pl) Test fluorescencyjny
WO2011153325A3 (en) Gene expression profiling for predicting the response to immunotherapy and/or the survivability of melanoma subjects
WO2009099905A3 (en) Molecular signatures and biomarkers associated with melanoma and methods of use thereof
HK1222597A1 (zh) 用於检测液体样本中的分析物的检测装置

Legal Events

Date Code Title Description
FG Grant or registration