MX2010005130A - Composiciones orales estanicas. - Google Patents
Composiciones orales estanicas.Info
- Publication number
- MX2010005130A MX2010005130A MX2010005130A MX2010005130A MX2010005130A MX 2010005130 A MX2010005130 A MX 2010005130A MX 2010005130 A MX2010005130 A MX 2010005130A MX 2010005130 A MX2010005130 A MX 2010005130A MX 2010005130 A MX2010005130 A MX 2010005130A
- Authority
- MX
- Mexico
- Prior art keywords
- ions
- chelants
- composition
- zinc
- divalent metal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a un composición oral acuosa que comprende: a) de 0.2 % a 3 % iones metálicos divalentes que comprenden: i. de 0.1 % a 1.5% de iones de zinc; ii. de 0.1 % a 2 % de iones de estaño (II); y b) un fuente de iones fluoruro; c) un abrasivo dental de sílice; d) uno o más quelantes que tienen un PM menor que 1000 y son capaces de formar complejos solubles en agua con los iones de zinc, en donde los quelantes comprenden menos de 0.2 % de polifosfatos lineales que tienen una longitud de cadena de cuatro o más; e) un portador oralmente aceptable que comprende al menos 20 % de agua total; en donde el pH de la composición es de 5 a 6.5, la relación molar de los quelantes a los iones metálicos divalentes es al menos 0.70:1 y al menos 80 % en peso de los iones totales de zinc están solubilizados dentro de la composición. Se ha descubierto que la composición de la invención proporciona una actividad antimicrobiana mejorada a partir de la combinación de zinc / estaño sin problemas de sabor, manchado o estabilidad significativos, comparada con las composiciones que tienen niveles menores de quelantes.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07120425 | 2007-11-09 | ||
| PCT/IB2008/054595 WO2009060385A2 (en) | 2007-11-09 | 2008-11-04 | Oral stannous compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010005130A true MX2010005130A (es) | 2010-08-04 |
Family
ID=39276045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010005130A MX2010005130A (es) | 2007-11-09 | 2008-11-04 | Composiciones orales estanicas. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8906347B2 (es) |
| EP (1) | EP2057978B1 (es) |
| JP (1) | JP5485160B2 (es) |
| CN (2) | CN101848694A (es) |
| AT (1) | ATE527978T1 (es) |
| AU (1) | AU2008326037B2 (es) |
| BR (1) | BRPI0820299B1 (es) |
| CA (1) | CA2703078C (es) |
| ES (1) | ES2375240T3 (es) |
| MX (1) | MX2010005130A (es) |
| RU (1) | RU2448680C2 (es) |
| WO (1) | WO2009060385A2 (es) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100189663A1 (en) * | 2009-01-24 | 2010-07-29 | Gallis Karl W | Mouth rinse compositions including chemically modified silica or silicate materials for sustained delivery to tooth surfaces |
| US20110236444A1 (en) * | 2010-03-25 | 2011-09-29 | Darsillo Michael S | Antimicrobial Silica Composites |
| SG183905A1 (en) | 2010-03-31 | 2012-10-30 | Colgate Palmolive Co | Oral care composition |
| DK2374446T3 (da) * | 2010-04-07 | 2013-05-13 | Gaba Int Holding Ag | Mundplejepræparat omfattende stanno- og nitrationer |
| CN104983593B (zh) * | 2010-11-04 | 2018-11-20 | 高露洁-棕榄公司 | 涩味降低的洁齿组合物 |
| CA2815459C (en) * | 2010-11-04 | 2017-09-26 | Colgate-Palmolive Company | Dentifrice composition with reduced astringency comprising a zinc salt, a halogenated diphenyl ether, and a chelating agent |
| AU2011359108B2 (en) * | 2011-02-18 | 2016-05-19 | Gaba International Holding Gmbh | Dentifrice composition |
| RU2578967C2 (ru) * | 2011-07-12 | 2016-03-27 | Дзе Проктер Энд Гэмбл Компани | Композиции для ухода за полостью рта, содержащие фитиновую кислоту |
| US9320691B2 (en) | 2011-09-09 | 2016-04-26 | GABA International Holdings AG | Stable compositions and methods for preparing the same |
| CA2892571C (en) * | 2012-12-24 | 2020-06-30 | Colgate-Palmolive Company | Oral care composition comprising stannous ions |
| CN104721063B (zh) | 2013-12-19 | 2018-05-08 | 高露洁-棕榄公司 | 包含氧化锌和柠檬酸锌的洁齿剂组合物 |
| CA2934503C (en) * | 2013-12-20 | 2021-03-02 | Colgate-Palmolive Company | Oral care compositions comprising an acrylate/methacrylate/hydroxyethyl methacrylate phosphate co-polymer and a tin salt |
| MX362471B (es) | 2014-05-14 | 2019-01-16 | Procter & Gamble | Composiciones para el cuidado bucal que tienen estabilidad mejorada. |
| PL3154503T3 (pl) | 2014-05-15 | 2018-12-31 | The Procter And Gamble Company | Kompozycje środków do czyszczenia zębów ze optymalizowanymi środkami konserwującymi |
| CN106232088B (zh) | 2014-05-15 | 2019-09-20 | 宝洁公司 | 具有改善的清新感的口腔护理组合物 |
| CN106232090B (zh) | 2014-05-15 | 2020-07-31 | 宝洁公司 | 包含聚乙二醇以提供物理稳定性的口腔护理组合物 |
| WO2015172348A1 (en) | 2014-05-15 | 2015-11-19 | The Procter & Gamble Company | Dentifrice compositions having dental plaque mitigation or improved fluoride uptake |
| WO2015172354A1 (en) | 2014-05-15 | 2015-11-19 | The Procter & Gamble Company | Dentifrice compositions having improved fluoride ion stability or fluoride uptake |
| EP3142628B1 (en) | 2014-05-15 | 2018-06-20 | The Procter and Gamble Company | Oral care compositions containing polyethylene glycol for physical stability |
| RU2670445C2 (ru) | 2014-06-18 | 2018-10-23 | Колгейт-Палмолив Компани | Средство для ухода за зубами, содержащее комплекс цинка с аминокислотой и фосфаты |
| RU2679416C2 (ru) | 2014-06-20 | 2019-02-08 | Колгейт-Палмолив Компани | Композиции для ухода за полостью рта, содержащие источники ионов цинка, олова (ii) и фторид-ионов |
| CN107075555B (zh) * | 2014-09-24 | 2021-12-03 | 高露洁-棕榄公司 | 金属离子的生物利用度 |
| EP3223914B1 (en) * | 2014-12-26 | 2020-05-06 | Colgate-Palmolive Company | Zinc phosphate complex |
| RU2692066C2 (ru) | 2014-12-26 | 2019-06-20 | Колгейт-Палмолив Компани | Комплекс фосфата цинка |
| RU2690157C2 (ru) | 2014-12-26 | 2019-05-31 | Колгейт-Палмолив Компани | Комплекс фосфата цинка для ухода за полостью рта |
| AU2014415217B2 (en) * | 2014-12-26 | 2018-11-29 | Colgate-Palmolive Company | Zinc phosphate complex |
| WO2016105438A1 (en) * | 2014-12-26 | 2016-06-30 | Colgate-Palmolive Company | Low water dentifrice compositions |
| WO2016105433A1 (en) | 2014-12-26 | 2016-06-30 | Colgate-Palmolive Company | Personal care compositions with zinc phosphate active |
| WO2017003844A1 (en) | 2015-07-01 | 2017-01-05 | Colgate-Palmolive Company | Oral care compositions and methods of use |
| JP2015227361A (ja) * | 2015-07-23 | 2015-12-17 | コルゲート・パーモリブ・カンパニーColgate−Palmolive Company | 減少した収斂性を有する歯磨剤組成物 |
| US10226407B2 (en) | 2015-12-30 | 2019-03-12 | Colgate-Palmolive Company | Oral care compositions |
| CN108472208B (zh) | 2015-12-30 | 2021-12-10 | 高露洁-棕榄公司 | 个人护理组合物 |
| AU2016380275C1 (en) | 2015-12-30 | 2019-11-28 | Colgate-Palmolive Company | Oral care compositions |
| MX370240B (es) | 2015-12-30 | 2019-12-06 | Colgate Palmolive Co | Composiciones para el cuidado personal. |
| WO2017219339A1 (en) | 2016-06-24 | 2017-12-28 | Colgate-Palmolive Company | Oral care compositions and methods of use |
| CN109328092A (zh) | 2016-06-24 | 2019-02-12 | 高露洁-棕榄公司 | 口腔护理组合物 |
| US10576029B2 (en) | 2016-06-24 | 2020-03-03 | Colgate-Palmolive Company | Oral care compositions |
| AU2017280200B2 (en) | 2016-06-24 | 2019-10-03 | Colgate-Palmolive Company | Oral care composition and method of use |
| AU2017281341B2 (en) * | 2016-06-24 | 2018-11-15 | Colgate-Palmolive Company | Oral care compositions |
| AU2017281230B2 (en) | 2016-06-24 | 2018-12-20 | Colgate-Palmolive Company | Oral care compositions and methods of using the compositions |
| BR112018005750B1 (pt) | 2016-06-24 | 2022-10-11 | Colgate-Palmolive Company | Composição para higiene bucal com teor elevado de água e uso relacionado a referida composição |
| BR112019012356B1 (pt) | 2016-12-21 | 2021-03-23 | Colgate-Palmolive Company | Composição para cuidado oral |
| BR112019012374B1 (pt) | 2016-12-21 | 2022-03-22 | Colgate-Palmolive Company | Composição para higiene bucal e uso desta |
| AU2017379609B2 (en) | 2016-12-21 | 2019-11-14 | Colgate-Palmolive Company | Oral care compositions |
| CN114948764B (zh) | 2016-12-21 | 2025-07-11 | 高露洁-棕榄公司 | 口腔护理组合物和使用方法 |
| AU2017382466B2 (en) | 2016-12-21 | 2020-03-05 | Colgate-Palmolive Company | Oral care compositions and methods of use |
| CN111867554B (zh) * | 2018-05-10 | 2023-06-30 | 狮王株式会社 | 口腔用组合物 |
| WO2020117721A2 (en) * | 2018-12-04 | 2020-06-11 | The Procter & Gamble Company | Oral care compositions with improved tin compatability |
| BR112021024304A2 (pt) | 2019-06-28 | 2022-01-11 | Procter & Gamble | Composições para tratamento bucal compreendendo íons de estanho |
| US11135141B2 (en) | 2019-06-28 | 2021-10-05 | The Procter & Gamble Company | Oral care compositions comprising tin ions |
| US12337048B2 (en) | 2019-06-28 | 2025-06-24 | The Procter & Gamble Company | Oral care compositions comprising tin ions |
| US11135143B2 (en) | 2020-06-25 | 2021-10-05 | The Procter & Gamble Company | Oral care compositions comprising tin ions |
| CN113950316B (zh) | 2019-07-01 | 2024-04-16 | 高露洁-棕榄公司 | 口腔护理组合物和方法 |
| WO2021062631A1 (en) * | 2019-09-30 | 2021-04-08 | The Procter & Gamble Company | Dentifrice compositions for treatment of dental biofilm |
| CN114502131B (zh) * | 2019-09-30 | 2024-08-13 | 宝洁公司 | 包含亚锡离子源、中性氨基酸和多磷酸盐的口腔护理组合物 |
| JP2023523309A (ja) * | 2020-05-05 | 2023-06-02 | ザ プロクター アンド ギャンブル カンパニー | 単座及び多座配位子を含む口腔ケア組成物 |
| US20210346260A1 (en) * | 2020-05-05 | 2021-11-11 | The Procter & Gamble Company | Oral Care Compositions Comprising Dicarboxylic Acid |
| AU2021268189A1 (en) * | 2020-05-05 | 2022-11-03 | The Procter & Gamble Company | Oral care compositions comprising dicarboxylic acid |
| EP4199884A1 (en) * | 2020-12-21 | 2023-06-28 | Colgate-Palmolive Company | Oral care compositions and methods |
| AU2021409652B2 (en) * | 2020-12-21 | 2025-04-10 | Colgate-Palmolive Company | Oral care compositions and methods |
| AU2021409793B2 (en) * | 2020-12-21 | 2025-04-17 | Colgate-Palmolive Company | Oral care compositions comprising stannous pyrophosphate and a water-soluble alkali metal polyphosphate, and methods |
| US12527735B2 (en) | 2021-08-23 | 2026-01-20 | Colgate-Palmolive Company | Oral care compositions and methods |
| EP4331563A1 (en) * | 2022-08-31 | 2024-03-06 | Unilever IP Holdings B.V. | Use of oral care composition |
| WO2025006606A2 (en) * | 2023-06-28 | 2025-01-02 | Colgate-Palmolive Company | Oral care compositions |
| CN119792115A (zh) * | 2025-02-10 | 2025-04-11 | 广州星际悦动股份有限公司 | 口腔护理组合物及其制备方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2946725A (en) | 1957-03-25 | 1960-07-26 | Procter & Gamble | Dentifrice compositions |
| US3070510A (en) | 1959-11-03 | 1962-12-25 | Procter & Gamble | Dentifrice containing resinous cleaning agents |
| US3282792A (en) | 1964-01-09 | 1966-11-01 | Bristol Myers Co | Stabilized stannous fluoride dentifrice compositions |
| US3538230A (en) | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
| US3678154A (en) | 1968-07-01 | 1972-07-18 | Procter & Gamble | Oral compositions for calculus retardation |
| US3535421A (en) | 1968-07-11 | 1970-10-20 | Procter & Gamble | Oral compositions for calculus retardation |
| US3862307A (en) | 1973-04-09 | 1975-01-21 | Procter & Gamble | Dentifrices containing a cationic therapeutic agent and improved silica abrasive |
| US4051234A (en) | 1975-06-06 | 1977-09-27 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
| US4340583A (en) | 1979-05-23 | 1982-07-20 | J. M. Huber Corporation | High fluoride compatibility dentifrice abrasives and compositions |
| JPS5846483B2 (ja) * | 1979-09-20 | 1983-10-17 | ライオン株式会社 | 口腔用組成物 |
| US5004597A (en) | 1987-09-14 | 1991-04-02 | The Procter & Gamble Company | Oral compositions comprising stannous flouride and stannous gluconate |
| GB8922434D0 (en) * | 1989-10-05 | 1989-11-22 | Unilever Plc | Oral compositions |
| GB8922594D0 (en) * | 1989-10-06 | 1989-11-22 | Unilever Plc | Oral compositions |
| US5213790A (en) | 1991-10-23 | 1993-05-25 | The Procter & Gamble Co. | Methods of reducing plaque and gingivitis with reduced staining |
| US5300289A (en) * | 1991-12-10 | 1994-04-05 | The Dow Chemical Company | Phytate antimicrobial compositions in oral care products |
| JPH08504816A (ja) | 1992-12-18 | 1996-05-28 | ザ、プロクター、エンド、ギャンブル、カンパニー | 抗歯垢、抗歯石剤を含有した口内組成物 |
| CA2151913A1 (en) | 1992-12-18 | 1994-07-07 | Ronald Earl Montgomery | Oral compositions containing antiplaque, anticalculus agents |
| US5603920A (en) | 1994-09-26 | 1997-02-18 | The Proctor & Gamble Company | Dentifrice compositions |
| US5578293A (en) | 1994-12-06 | 1996-11-26 | Colgate Palmolive Company | Oral compositions containing stabilized stannous compounds having antiplaque and antitartar efficacy |
| US5658553A (en) | 1995-05-02 | 1997-08-19 | The Procter & Gamble Company | Dentifrice compositions |
| US5589160A (en) | 1995-05-02 | 1996-12-31 | The Procter & Gamble Company | Dentifrice compositions |
| US5651958A (en) | 1995-05-02 | 1997-07-29 | The Procter & Gamble Company | Dentifrice compositions |
| GB9517031D0 (en) | 1995-08-19 | 1995-10-25 | Procter & Gamble | Confection compositions |
| US20030206874A1 (en) * | 1996-11-21 | 2003-11-06 | The Proctor & Gamble Company | Promoting whole body health |
| US6221340B1 (en) | 1999-04-08 | 2001-04-24 | Warner-Lambert Company | Zinc containing dentifrice compositions |
| ES2350177T3 (es) * | 1999-11-12 | 2011-01-19 | THE PROCTER & GAMBLE COMPANY | Composiciones orales que contienen iones estannosos. |
| US6685920B2 (en) * | 1999-11-12 | 2004-02-03 | The Procter & Gamble Company | Method of protecting teeth against erosion |
| US20070025928A1 (en) * | 1999-11-12 | 2007-02-01 | The Procter & Gamble Company | Stannous oral care compositions |
| EP1399121B1 (en) | 2001-06-25 | 2008-11-05 | The Procter & Gamble Company | Oral care compositions |
| JP4800576B2 (ja) * | 2001-11-28 | 2011-10-26 | ザ プロクター アンド ギャンブル カンパニー | ポリリン酸塩及びイオン性活性成分を含む安定な低水相を含む歯磨剤組成物 |
| KR20080070757A (ko) * | 2005-12-20 | 2008-07-30 | 더 프록터 앤드 갬블 캄파니 | 아연 및 피테이트를 함유하는 구강 케어 조성물 |
| CN101495085A (zh) * | 2006-04-07 | 2009-07-29 | 宝洁公司 | 口部护理方案及套盒 |
-
2008
- 2008-11-04 MX MX2010005130A patent/MX2010005130A/es active IP Right Grant
- 2008-11-04 CN CN200880115025A patent/CN101848694A/zh active Pending
- 2008-11-04 AU AU2008326037A patent/AU2008326037B2/en active Active
- 2008-11-04 RU RU2010115240/15A patent/RU2448680C2/ru not_active IP Right Cessation
- 2008-11-04 BR BRPI0820299A patent/BRPI0820299B1/pt active IP Right Grant
- 2008-11-04 WO PCT/IB2008/054595 patent/WO2009060385A2/en not_active Ceased
- 2008-11-04 CA CA2703078A patent/CA2703078C/en active Active
- 2008-11-04 JP JP2010530625A patent/JP5485160B2/ja not_active Expired - Fee Related
- 2008-11-04 CN CN201510160757.1A patent/CN104784056A/zh active Pending
- 2008-11-05 AT AT08168355T patent/ATE527978T1/de not_active IP Right Cessation
- 2008-11-05 ES ES08168355T patent/ES2375240T3/es active Active
- 2008-11-05 EP EP08168355A patent/EP2057978B1/en active Active
- 2008-11-07 US US12/266,937 patent/US8906347B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2057978B1 (en) | 2011-10-12 |
| CN104784056A (zh) | 2015-07-22 |
| US8906347B2 (en) | 2014-12-09 |
| WO2009060385A3 (en) | 2009-07-30 |
| AU2008326037B2 (en) | 2014-05-01 |
| US20090136432A1 (en) | 2009-05-28 |
| EP2057978A1 (en) | 2009-05-13 |
| BRPI0820299B1 (pt) | 2016-07-26 |
| JP2011500791A (ja) | 2011-01-06 |
| ES2375240T3 (es) | 2012-02-28 |
| RU2010115240A (ru) | 2011-12-20 |
| JP5485160B2 (ja) | 2014-05-07 |
| CA2703078C (en) | 2013-05-21 |
| RU2448680C2 (ru) | 2012-04-27 |
| ATE527978T1 (de) | 2011-10-15 |
| CA2703078A1 (en) | 2009-05-14 |
| CN101848694A (zh) | 2010-09-29 |
| WO2009060385A2 (en) | 2009-05-14 |
| AU2008326037A1 (en) | 2009-05-14 |
| BRPI0820299A2 (pt) | 2014-09-30 |
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