MX2010004389A - Formulaciones de vancomicina liposomales. - Google Patents
Formulaciones de vancomicina liposomales.Info
- Publication number
- MX2010004389A MX2010004389A MX2010004389A MX2010004389A MX2010004389A MX 2010004389 A MX2010004389 A MX 2010004389A MX 2010004389 A MX2010004389 A MX 2010004389A MX 2010004389 A MX2010004389 A MX 2010004389A MX 2010004389 A MX2010004389 A MX 2010004389A
- Authority
- MX
- Mexico
- Prior art keywords
- liposomal vancomycin
- vancomycin formulations
- liposomal
- present disclosure
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 108010059993 Vancomycin Proteins 0.000 title abstract 2
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 title abstract 2
- 229960003165 vancomycin Drugs 0.000 title abstract 2
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- MYPYJXKWCTUITO-KIIOPKALSA-N chembl3301825 Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)C(O)[C@H](C)O1 MYPYJXKWCTUITO-KIIOPKALSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente descripción se refiere en parte a composiciones de vancomicina liposomales que tienen bajas relaciones de lípidos a fármacos y alta concentración de vancomicina. La presente descripción también se refiere en parte a métodos para formar dichas composiciones.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98199007P | 2007-10-23 | 2007-10-23 | |
| US10372508P | 2008-10-08 | 2008-10-08 | |
| PCT/US2008/080954 WO2009055568A2 (en) | 2007-10-23 | 2008-10-23 | Liposomal vancomycin formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010004389A true MX2010004389A (es) | 2010-05-20 |
Family
ID=40563728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010004389A MX2010004389A (es) | 2007-10-23 | 2008-10-23 | Formulaciones de vancomicina liposomales. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20090105126A1 (es) |
| EP (1) | EP2214645A4 (es) |
| JP (3) | JP5855829B2 (es) |
| CN (2) | CN103860469A (es) |
| AU (2) | AU2008316841B2 (es) |
| CA (1) | CA2703179C (es) |
| MX (1) | MX2010004389A (es) |
| WO (2) | WO2009055568A2 (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2594368T3 (es) | 2005-12-08 | 2016-12-19 | Insmed Incorporated | Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| WO2011146829A1 (en) * | 2010-05-20 | 2011-11-24 | Cempra Pharmaceuticals, Inc. | Processes for preparing macrolides and ketolides and intermediates therefor |
| AU2011268101B2 (en) * | 2010-06-19 | 2014-09-25 | Western University Of Health Sciences | Novel formulation of pegylated-liposome encapsulated glycopeptide antibiotics |
| JPWO2012020790A1 (ja) * | 2010-08-11 | 2013-10-28 | 学校法人慶應義塾 | 感染症治療薬 |
| WO2012054447A2 (en) * | 2010-10-22 | 2012-04-26 | Dr. Reddy's Laboratories, Inc. | Use of storage stable viscous phospholipid depot to treat wounds |
| MX2013012603A (es) * | 2011-04-26 | 2014-04-25 | Cedars Sinai Medical Center | Vancomicina liposomal para el tratamiento de infecciones por estafilococo aureus resistente a la meticilina (sarm). |
| US9572774B2 (en) | 2011-05-19 | 2017-02-21 | Savara Inc. | Dry powder vancomycin compositions and associated methods |
| JP5932993B2 (ja) * | 2011-06-17 | 2016-06-08 | バーグ エルエルシー | 吸入可能な医薬組成物 |
| ES2743039T3 (es) * | 2012-11-29 | 2020-02-18 | Insmed Inc | Formulaciones de vancomicina estabilizada |
| ES2926985T3 (es) | 2014-05-15 | 2022-10-31 | Insmed Inc | Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas |
| US20170065520A1 (en) * | 2015-09-09 | 2017-03-09 | Manli International Ltd | Stable liposomal formulations of rapamycin and rapamycin derivatives for treating cancer |
| PL3373910T3 (pl) * | 2015-11-10 | 2023-10-09 | Children's Research Institute, Children's National Medical Center | Preparat echinomycyny, sposób wytwarzania i sposób stosowania |
| CN108601730B (zh) * | 2016-01-15 | 2021-10-26 | 赛多斯制药有限责任公司 | 万古霉素的制剂 |
| CN116549393A (zh) * | 2017-03-02 | 2023-08-08 | 康柏辛股份有限公司 | 抑制生物膜形成的脂质体 |
| NZ758839A (en) | 2017-05-22 | 2025-08-29 | Insmed Inc | Glycopeptide derivative compounds and uses thereof |
| US20200368313A1 (en) * | 2017-12-29 | 2020-11-26 | Wayne State University | Drug delivery systems for treatment of infections |
| EP3773505A4 (en) | 2018-03-30 | 2021-12-22 | Insmed Incorporated | PROCESS FOR THE CONTINUOUS MANUFACTURING OF LIPOSOMAL MEDICINAL PRODUCTS |
| CA3098573A1 (en) | 2018-05-02 | 2019-11-07 | Insmed Incorporated | Methods for the manufacture of liposomal drug formulations |
| CN109078001B (zh) * | 2018-09-21 | 2021-05-07 | 深圳浦瑞健康科技有限公司 | 一种万古霉素纳米脂质体组合物及其制备方法 |
| EP3883589A4 (en) * | 2018-11-21 | 2022-05-25 | Insmed Incorporated | LIPO-GLYCOPEPTIDE CLEAVABLE DERIVATIVES AND USES THEREOF |
| WO2020242996A1 (en) * | 2019-05-28 | 2020-12-03 | Nevakar Inc. | Vancomycin liposome compositions and methods |
| CN119499182B (zh) * | 2024-11-28 | 2025-08-26 | 西藏农牧学院 | 一种黄枝瑚菌多糖脂质体及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9203504A (es) * | 1988-04-20 | 1992-07-01 | Liposome Co Inc | Complejo agente: lipido activo de alta proporcion. |
| JPH06345663A (ja) * | 1993-06-08 | 1994-12-20 | Sumitomo Pharmaceut Co Ltd | バンコマイシン含有リポソーム製剤 |
| US7718189B2 (en) * | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| NZ540087A (en) * | 2002-10-29 | 2008-09-26 | Transave Inc | Sustained release of antiinfectives |
| US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
| CA2506749A1 (en) * | 2002-11-26 | 2004-06-10 | Gilead Sciences, Inc. | Method of drug loading in liposomes by gradient |
| US20070105756A1 (en) * | 2005-10-31 | 2007-05-10 | May Thomas B | Vancomycin formulations having reduced amount of histamine |
-
2008
- 2008-10-23 WO PCT/US2008/080954 patent/WO2009055568A2/en not_active Ceased
- 2008-10-23 AU AU2008316841A patent/AU2008316841B2/en not_active Ceased
- 2008-10-23 CA CA2703179A patent/CA2703179C/en not_active Expired - Fee Related
- 2008-10-23 CN CN201410050891.1A patent/CN103860469A/zh active Pending
- 2008-10-23 US US12/256,696 patent/US20090105126A1/en not_active Abandoned
- 2008-10-23 JP JP2010531241A patent/JP5855829B2/ja not_active Expired - Fee Related
- 2008-10-23 US US12/256,692 patent/US20090104257A1/en not_active Abandoned
- 2008-10-23 WO PCT/US2008/080959 patent/WO2009055571A2/en not_active Ceased
- 2008-10-23 CN CN2008801233251A patent/CN101917972A/zh active Pending
- 2008-10-23 EP EP08840993.3A patent/EP2214645A4/en not_active Withdrawn
- 2008-10-23 MX MX2010004389A patent/MX2010004389A/es active IP Right Grant
-
2014
- 2014-02-25 JP JP2014033713A patent/JP2014098032A/ja not_active Withdrawn
- 2014-05-20 AU AU2014202745A patent/AU2014202745B2/en not_active Ceased
-
2016
- 2016-04-18 JP JP2016082745A patent/JP2016130262A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN103860469A (zh) | 2014-06-18 |
| EP2214645A4 (en) | 2013-09-25 |
| JP2011500836A (ja) | 2011-01-06 |
| JP2014098032A (ja) | 2014-05-29 |
| CN101917972A (zh) | 2010-12-15 |
| AU2014202745A1 (en) | 2014-06-12 |
| JP2016130262A (ja) | 2016-07-21 |
| AU2008316841A1 (en) | 2009-04-30 |
| WO2009055568A2 (en) | 2009-04-30 |
| CA2703179C (en) | 2016-06-07 |
| US20090105126A1 (en) | 2009-04-23 |
| WO2009055571A2 (en) | 2009-04-30 |
| CA2703179A1 (en) | 2009-04-30 |
| WO2009055568A3 (en) | 2009-09-24 |
| EP2214645A2 (en) | 2010-08-11 |
| JP5855829B2 (ja) | 2016-02-09 |
| AU2014202745B2 (en) | 2016-11-24 |
| AU2008316841B2 (en) | 2014-04-17 |
| US20090104257A1 (en) | 2009-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |