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MX2010004054A - Derivados de imidazol novedosos. - Google Patents

Derivados de imidazol novedosos.

Info

Publication number
MX2010004054A
MX2010004054A MX2010004054A MX2010004054A MX2010004054A MX 2010004054 A MX2010004054 A MX 2010004054A MX 2010004054 A MX2010004054 A MX 2010004054A MX 2010004054 A MX2010004054 A MX 2010004054A MX 2010004054 A MX2010004054 A MX 2010004054A
Authority
MX
Mexico
Prior art keywords
sup
halogen
imidazole derivatives
c4alkyl
novel imidazole
Prior art date
Application number
MX2010004054A
Other languages
English (en)
Inventor
Stephan Trah
Clemens Lamberth
Sebastian Volker Wendeborn
Raphael Dumeunier
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of MX2010004054A publication Critical patent/MX2010004054A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La presente invenci?n se refiere a derivados de imidazol novedosos de f?rmula I como ingredientes activos los cuales tienen actividad microbicida, en particular actividad fungicida: (ver f?rmula (I)) donde R1 es hal?geno, alquilo C1-C4 o haloalquilo C1-C4; R2 es un arilo o heteroarilo opcionalmente sustituido; R3 es hal?geno; R4 es hidr?geno, hal?geno, alquilo C1-C4, haloalquilo C1-C4, alcoxi C1-C4, haloalcoxi C1-C4 o ciano; R5 es hal?geno; X es N o C(R); y R es hidr?geno, hal?geno, alquilo C1-C4, haloalquilo C1-C4, alcoxi C1-C4, haloalcoxi C1-C4 o ciano; o su forma de sal agroqu?micamente utilizable; siempre y cuando X sea C(R), R2 no puede ser un arilo opcionalmente sustituido.
MX2010004054A 2007-10-26 2008-10-24 Derivados de imidazol novedosos. MX2010004054A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07020982A EP2053045A1 (en) 2007-10-26 2007-10-26 Novel imidazole derivatives
EP07024449 2007-12-17
PCT/EP2008/009043 WO2009053102A1 (en) 2007-10-26 2008-10-24 Novel imidazole derivatives

Publications (1)

Publication Number Publication Date
MX2010004054A true MX2010004054A (es) 2010-04-30

Family

ID=39186125

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010004054A MX2010004054A (es) 2007-10-26 2008-10-24 Derivados de imidazol novedosos.

Country Status (6)

Country Link
EP (2) EP2053045A1 (es)
AU (1) AU2008315562A1 (es)
CA (1) CA2701747A1 (es)
ES (1) ES2370098T3 (es)
MX (1) MX2010004054A (es)
WO (1) WO2009053102A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20091953A1 (es) * 2008-05-08 2010-01-09 Du Pont Azoles sustituidos como fungicidas
AU2010234526B2 (en) 2009-04-06 2016-07-21 Agios Pharmaceuticals, Inc. Pyruvate kinase M2 modulators, therapeutic compositions and related methods of use
EP2443121A2 (en) * 2009-06-16 2012-04-25 Schering Corporation Gamma secretase modulators
JP5856052B2 (ja) 2009-06-29 2016-02-09 アジオス ファーマシューティカルズ， インコーポレイテッド 治療化合物および組成物
EP2448581B1 (en) 2009-06-29 2016-12-07 Agios Pharmaceuticals, Inc. Therapeutic compositions and related methods of use
TW201117722A (en) * 2009-11-04 2011-06-01 Du Pont Fungicidal mixtures
BR112013007635A2 (pt) 2010-09-29 2016-07-26 Du Pont ''composto selecionados da fórmula 1, composição fungicida e método para controlar doenças de planta''
US9221792B2 (en) 2010-12-17 2015-12-29 Agios Pharmaceuticals, Inc N-(4-(azetidine-1-carbonyl) phenyl)-(hetero-) arylsulfonamide derivatives as pyruvate kinase M2 (PMK2) modulators
CA2822432C (en) 2010-12-21 2019-09-24 Agios Pharmaceuticals, Inc. Bicyclic pkm2 activators
TWI549947B (zh) 2010-12-29 2016-09-21 阿吉歐斯製藥公司 治療化合物及組成物
US9181231B2 (en) 2011-05-03 2015-11-10 Agios Pharmaceuticals, Inc Pyruvate kinase activators for use for increasing lifetime of the red blood cells and treating anemia
PH12017501176B1 (en) 2011-05-03 2023-03-08 Agios Pharmaceuticals Inc Pyruvate kinase activators for use in therapy
WO2014139144A1 (en) 2013-03-15 2014-09-18 Agios Pharmaceuticals, Inc. Therapeutic compounds and compositions
HUE063541T2 (hu) 2015-06-11 2024-01-28 Agios Pharmaceuticals Inc Eljárások piruvát-kináz aktivátorok alkalmazására

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3261873A (en) * 1961-08-04 1966-07-19 Dow Chemical Co Substituted 2-halo-4-aminoimidazoles and preparatory process
CA1340685C (en) 1988-07-29 1999-07-27 Frederick Meins Dna sequences encoding polypeptides having beta-1,3-glucanase activity
EP0392225B1 (en) 1989-03-24 2003-05-28 Syngenta Participations AG Disease-resistant transgenic plants
US5639949A (en) 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
EA001148B1 (ru) 1996-03-11 2000-10-30 Новартис Аг Производные пиримидин-4-она
TWI252231B (en) 1997-04-14 2006-04-01 American Cyanamid Co Fungicidal trifluorophenyl-triazolopyrimidines
PL338191A1 (en) * 1997-07-24 2000-10-09 Bayer Ag Nitrophenylsulphonyl imidazoles and their application in fighting against plant and animal pests
DE10215292A1 (de) 2002-02-19 2003-08-28 Bayer Cropscience Ag Disubstitutierte Pyrazolylcarbocanilide
BR0308230B1 (pt) 2002-03-05 2014-05-20 Syngenta Participations Ag O-ciclopropil-carboxanilida, composição e método de controle ou prevenção de infestação de plantas cultivadas por microorganismos fitopatogênicos
WO2004016088A2 (en) 2002-08-12 2004-02-26 Bayer Cropscience S.A. Novel 2-pyridylethylbenzamide derivative
GB0224316D0 (en) 2002-10-18 2002-11-27 Syngenta Participations Ag Chemical compounds
WO2004052280A2 (en) 2002-12-10 2004-06-24 Imclone Systems Incorporated Anti-angiogenic compounds and their use in cancer treatment
EP1720862A1 (en) * 2004-02-03 2006-11-15 Eli Lilly And Company Kinase inhibitors
WO2005121104A1 (ja) 2004-06-09 2005-12-22 Sumitomo Chemical Company, Limited ピリダジン化合物及びその用途
ATE488506T1 (de) 2004-06-28 2010-12-15 Sumitomo Chemical Co Pyridazinverbindung und deren verwendung
GB0422401D0 (en) 2004-10-08 2004-11-10 Syngenta Participations Ag Fungicidal compositions
RU2416609C2 (ru) 2005-12-07 2011-04-20 Сумитомо Кемикал Компани, Лимитед Соединение пиридазина и его применение

Also Published As

Publication number Publication date
ES2370098T3 (es) 2011-12-12
AU2008315562A1 (en) 2009-04-30
CA2701747A1 (en) 2009-04-30
EP2201000A1 (en) 2010-06-30
EP2053045A1 (en) 2009-04-29
WO2009053102A1 (en) 2009-04-30
EP2201000B1 (en) 2011-08-31

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