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MX2010002680A - Uso de derivados de purina para la manufactura de un medicamento. - Google Patents

Uso de derivados de purina para la manufactura de un medicamento.

Info

Publication number
MX2010002680A
MX2010002680A MX2010002680A MX2010002680A MX2010002680A MX 2010002680 A MX2010002680 A MX 2010002680A MX 2010002680 A MX2010002680 A MX 2010002680A MX 2010002680 A MX2010002680 A MX 2010002680A MX 2010002680 A MX2010002680 A MX 2010002680A
Authority
MX
Mexico
Prior art keywords
medicament
manufacture
purine derivatives
apoptosis
purine
Prior art date
Application number
MX2010002680A
Other languages
English (en)
Inventor
Laurent Meijer
Karima Bettayeb
Herve Galons
Nassima Oumata
Christian Berthou
Karine Lester
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of MX2010002680A publication Critical patent/MX2010002680A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención se refiere al uso de los derivados de purina en la manufactura de un medicamento para tratar las patologías en las cuales está implicado un desequilibrio entre la división celular y la apoptosis, y más particularmente en el cual una apoptosis excesiva es el origen de las patologías. De acuerdo a la invención, un derivado de purina de la fórmula I es utilizado. La invención encuentra aplicación en el dominio farmacéutico.
MX2010002680A 2007-09-12 2008-09-12 Uso de derivados de purina para la manufactura de un medicamento. MX2010002680A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0706390A FR2920776B1 (fr) 2007-09-12 2007-09-12 Utilisation de derives de purine pour la fabrication d'un medicament
PCT/FR2008/001278 WO2009068761A2 (fr) 2007-09-12 2008-09-12 Utilisation de derives de purine pour la fabrication d'un medicament

Publications (1)

Publication Number Publication Date
MX2010002680A true MX2010002680A (es) 2010-08-26

Family

ID=39382006

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010002680A MX2010002680A (es) 2007-09-12 2008-09-12 Uso de derivados de purina para la manufactura de un medicamento.

Country Status (13)

Country Link
US (1) US8431583B2 (es)
EP (1) EP2187889B1 (es)
JP (1) JP5485893B2 (es)
KR (1) KR20100075908A (es)
CN (1) CN101918000B (es)
BR (1) BRPI0816810A2 (es)
CA (1) CA2699590A1 (es)
DK (1) DK2187889T3 (es)
ES (1) ES2444419T3 (es)
FR (1) FR2920776B1 (es)
MX (1) MX2010002680A (es)
RU (1) RU2500400C2 (es)
WO (1) WO2009068761A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2920776B1 (fr) 2007-09-12 2012-09-28 Centre Nat Rech Scient Utilisation de derives de purine pour la fabrication d'un medicament
WO2010103473A1 (en) * 2009-03-10 2010-09-16 Chu De Brest Method of treatment of polycystic diseases and chronic lymphocytic leukemia
WO2013130461A1 (en) * 2012-02-29 2013-09-06 The Scripps Research Institute Wee1 degradation inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866702A (en) * 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2
US6969720B2 (en) * 1999-03-17 2005-11-29 Amr Technology, Inc. Biaryl substituted purine derivatives as potent antiproliferative agents
US6627633B2 (en) * 1999-03-17 2003-09-30 Albany Molecular Research, Inc. 6-substituted biaryl purine derivatives as potent cyclin/CDK inhibitors and antiproliferative agents
JP4381804B2 (ja) 2001-06-27 2009-12-09 サイクラセル リミテッド ２，６，９−置換プリン誘導体及び増殖性疾患の治療におけるその使用
US6667311B2 (en) * 2001-09-11 2003-12-23 Albany Molecular Research, Inc. Nitrogen substituted biaryl purine derivatives as potent antiproliferative agents
US6812232B2 (en) 2001-09-11 2004-11-02 Amr Technology, Inc. Heterocycle substituted purine derivatives as potent antiproliferative agents
GB0315259D0 (en) 2003-06-30 2003-08-06 Cyclacel Ltd Use
JP2007502776A (ja) * 2003-08-15 2007-02-15 アイアールエム・リミテッド・ライアビリティ・カンパニー Ｒｔｋ阻害剤としての６−置換アニリノプリン類
FR2920776B1 (fr) 2007-09-12 2012-09-28 Centre Nat Rech Scient Utilisation de derives de purine pour la fabrication d'un medicament

Also Published As

Publication number Publication date
CA2699590A1 (fr) 2009-06-04
EP2187889B1 (fr) 2013-11-06
FR2920776A1 (fr) 2009-03-13
CN101918000A (zh) 2010-12-15
WO2009068761A3 (fr) 2010-01-07
KR20100075908A (ko) 2010-07-05
FR2920776B1 (fr) 2012-09-28
WO2009068761A2 (fr) 2009-06-04
JP2010539146A (ja) 2010-12-16
JP5485893B2 (ja) 2014-05-07
RU2010108505A (ru) 2011-10-20
ES2444419T3 (es) 2014-02-25
US20100311768A1 (en) 2010-12-09
CN101918000B (zh) 2012-11-21
EP2187889A2 (fr) 2010-05-26
DK2187889T3 (da) 2014-02-03
BRPI0816810A2 (pt) 2017-05-16
US8431583B2 (en) 2013-04-30
RU2500400C2 (ru) 2013-12-10

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