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MX2010001187A - Modulators of ccr9 receptor and methods of use thereof. - Google Patents

Modulators of ccr9 receptor and methods of use thereof.

Info

Publication number
MX2010001187A
MX2010001187A MX2010001187A MX2010001187A MX2010001187A MX 2010001187 A MX2010001187 A MX 2010001187A MX 2010001187 A MX2010001187 A MX 2010001187A MX 2010001187 A MX2010001187 A MX 2010001187A MX 2010001187 A MX2010001187 A MX 2010001187A
Authority
MX
Mexico
Prior art keywords
methods
modulators
ccr9 receptor
compounds
ccr9
Prior art date
Application number
MX2010001187A
Other languages
Spanish (es)
Inventor
Eric C Anderson
Ronald J Biediger
Jie Chen
Brian Dupre
Pedro Lory
Robert V Market
Keith A Monk
Michael M Savage
Reginald Tennyson
Brandon M Young
Original Assignee
Encysive Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Encysive Pharmaceuticals Inc filed Critical Encysive Pharmaceuticals Inc
Publication of MX2010001187A publication Critical patent/MX2010001187A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Provided are compounds that are modulators of CCR9 receptor activity, compositions containing the compounds and methods of use of the compounds and compositions. In certain embodiments, provided are methods for treating or ameliorating diseases associated with modulation of CCR9 receptor activity.
MX2010001187A 2007-07-30 2008-07-28 Modulators of ccr9 receptor and methods of use thereof. MX2010001187A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96264007P 2007-07-30 2007-07-30
PCT/US2008/009142 WO2009017719A2 (en) 2007-07-30 2008-07-28 Modulators of ccr9 receptor and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2010001187A true MX2010001187A (en) 2010-03-04

Family

ID=40305125

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001187A MX2010001187A (en) 2007-07-30 2008-07-28 Modulators of ccr9 receptor and methods of use thereof.

Country Status (7)

Country Link
EP (1) EP2220065A2 (en)
KR (1) KR20100033418A (en)
AU (1) AU2008282903B2 (en)
CA (1) CA2692013C (en)
MX (1) MX2010001187A (en)
SG (1) SG183667A1 (en)
WO (1) WO2009017719A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010204118B2 (en) 2009-01-12 2012-12-20 Icagen, Inc. Sulfonamide derivatives
WO2011133729A2 (en) * 2010-04-23 2011-10-27 Kineta, Inc. Anti-viral compounds
CA2804173C (en) 2010-07-09 2015-01-13 Pfizer Limited Sulfonamide nav1.7 inhibitors
AU2011316550A1 (en) * 2010-10-12 2013-05-02 Zafgen, Inc Sulphonamide compounds and methods of making and using same
TW201512171A (en) 2013-04-19 2015-04-01 Pfizer Ltd Chemical compounds
KR20240087654A (en) * 2021-10-28 2024-06-19 시코쿠가세이고교가부시키가이샤 Thiophene compounds, methods for synthesizing the same and compositions containing the thiophene compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001503037A (en) * 1996-10-16 2001-03-06 アメリカン・サイアナミド・カンパニー Preparation and use of ortho-sulfonamidoheteroarylhydroxamic acids as inhibitors of matrix metalloproteinases and tace
JP3972163B2 (en) * 1999-06-18 2007-09-05 株式会社大塚製薬工場 Phosphonic acid diester derivatives
EP2415760A3 (en) * 2003-02-20 2012-02-22 Encysive Pharmaceuticals, Inc. CCR-9 antagonists

Also Published As

Publication number Publication date
AU2008282903B2 (en) 2011-06-30
SG183667A1 (en) 2012-09-27
WO2009017719A2 (en) 2009-02-05
AU2008282903A1 (en) 2009-02-05
WO2009017719A8 (en) 2010-02-11
EP2220065A2 (en) 2010-08-25
WO2009017719A3 (en) 2009-04-23
CA2692013A1 (en) 2009-02-05
CA2692013C (en) 2012-08-28
KR20100033418A (en) 2010-03-29

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal