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MX2009014104A - Metodos para sintetizar cinacalcet y sales del mismo. - Google Patents

Metodos para sintetizar cinacalcet y sales del mismo.

Info

Publication number
MX2009014104A
MX2009014104A MX2009014104A MX2009014104A MX2009014104A MX 2009014104 A MX2009014104 A MX 2009014104A MX 2009014104 A MX2009014104 A MX 2009014104A MX 2009014104 A MX2009014104 A MX 2009014104A MX 2009014104 A MX2009014104 A MX 2009014104A
Authority
MX
Mexico
Prior art keywords
cinacalcet
methods
salts
disclosed
synthesizing
Prior art date
Application number
MX2009014104A
Other languages
English (en)
Inventor
Michael John Martinelli
Oliver Thiel
Charles Bernard
Robert Larsen
Masooma Tamim Raza
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2009014104A publication Critical patent/MX2009014104A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C07C209/70—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by reduction of unsaturated amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
    • C07C209/22—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of other functional groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Aqu? se describen m?todos para preparar cinacalcet, derivados de cinacalcet y sales del mismo. Tambi?n se describen polimorfos de cinacalcet, composiciones de cinacalcet y los m?todos de tratamiento para un sujeto por la administraci?n de cinacalcet, donde el cinacalcet se prepara por los m?todos aqu? descritos.
MX2009014104A 2007-06-21 2008-06-19 Metodos para sintetizar cinacalcet y sales del mismo. MX2009014104A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94544307P 2007-06-21 2007-06-21
PCT/US2008/007621 WO2009002427A2 (en) 2007-06-21 2008-06-19 Methods of synthesizing cinacalcet and salts thereof

Publications (1)

Publication Number Publication Date
MX2009014104A true MX2009014104A (es) 2010-04-21

Family

ID=39817082

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009014104A MX2009014104A (es) 2007-06-21 2008-06-19 Metodos para sintetizar cinacalcet y sales del mismo.

Country Status (8)

Country Link
US (2) US20090137837A1 (es)
EP (1) EP2170805B1 (es)
JP (1) JP5358566B2 (es)
AU (1) AU2008269181B2 (es)
CA (1) CA2691196C (es)
ES (1) ES2569483T3 (es)
MX (1) MX2009014104A (es)
WO (1) WO2009002427A2 (es)

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WO2010015935A2 (en) * 2008-08-06 2010-02-11 Actavis Group Ptc Ehf Unsaturated cinacalcet salts and processes for preparing cinacalcet hydrochloride
WO2010067204A1 (en) * 2008-12-08 2010-06-17 Actavis Group Ptc Ehf Highly pure cinacalcet or a pharmaceutically acceptable salt thereof
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TW201615194A (zh) * 2014-10-24 2016-05-01 朗齊生物醫學股份有限公司 氨苯蝶啶藥物應用於癌症治療
CN106831441B (zh) * 2017-01-23 2019-04-02 江苏康思尔医药科技有限公司 一种盐酸西那卡塞的制备方法
WO2018224455A1 (en) 2017-06-07 2018-12-13 Basf Se Substituted cyclopropyl derivatives
US11612666B2 (en) 2017-11-30 2023-03-28 Seagen Inc. Process for the preparation of drug linker compounds
CN110963945A (zh) * 2019-12-25 2020-04-07 江苏正大清江制药有限公司 西那卡塞中间体杂质的制备及分离纯化方法
CN114195671B (zh) * 2021-12-27 2023-09-22 河南师范大学 一种不对称丙二酰苯胺类化合物及其合成方法

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Also Published As

Publication number Publication date
CA2691196A1 (en) 2008-12-31
CA2691196C (en) 2016-05-24
ES2569483T3 (es) 2016-05-11
EP2170805A2 (en) 2010-04-07
US8183415B2 (en) 2012-05-22
US20090137837A1 (en) 2009-05-28
JP2010530428A (ja) 2010-09-09
JP5358566B2 (ja) 2013-12-04
WO2009002427A3 (en) 2009-07-30
EP2170805B1 (en) 2016-03-16
WO2009002427A2 (en) 2008-12-31
US20110281954A1 (en) 2011-11-17
AU2008269181A1 (en) 2008-12-31
AU2008269181B2 (en) 2014-04-17

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