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MX2009013305A - Composicion farmaceutica de un nuevo sistema para liberacion vaginal de esteroides. - Google Patents

Composicion farmaceutica de un nuevo sistema para liberacion vaginal de esteroides.

Info

Publication number
MX2009013305A
MX2009013305A MX2009013305A MX2009013305A MX2009013305A MX 2009013305 A MX2009013305 A MX 2009013305A MX 2009013305 A MX2009013305 A MX 2009013305A MX 2009013305 A MX2009013305 A MX 2009013305A MX 2009013305 A MX2009013305 A MX 2009013305A
Authority
MX
Mexico
Prior art keywords
steroids
vaginal
pharmaceutical composition
new system
vaginal release
Prior art date
Application number
MX2009013305A
Other languages
English (en)
Inventor
Ariel Fuentes
Luigi Devoto
Ricardo Pomer
Hugo Sovino
Pablo C Spedes
Leon Trejo
Original Assignee
Univ Chile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Chile filed Critical Univ Chile
Publication of MX2009013305A publication Critical patent/MX2009013305A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen composiciones farmac?uticas apropiadas para la administraci?n vaginal ce esteroides, para ser utilizadas en una terapia de reemplazo de hormonas, durante la menopausia y para soportar la fase l?tea de los ciclos de fertilizaci?n in vitro. Las composiciones se caracterizan por la incorporaci?n de combinaciones de pol?meros y desintegradores, que permiten una adherencia a la mucosa adecuada y bio-disponibilidad de las hormonas esteroides en el endometrio. Este m?todo de administraci?n reduce los niveles sist?micos de esteroides, permite un plazo m?s largo entre las dosis, reduciendo de esta manera los efectos secundarios, y previene la acumulaci?n de residuos dentro de la cavidad vaginal.
MX2009013305A 2007-06-06 2008-06-04 Composicion farmaceutica de un nuevo sistema para liberacion vaginal de esteroides. MX2009013305A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CL2007001634 2007-06-06
PCT/US2008/065722 WO2008154240A1 (en) 2007-06-06 2008-06-04 Pharmaceutical composition of a new system for vaginal release of steroids

Publications (1)

Publication Number Publication Date
MX2009013305A true MX2009013305A (es) 2010-04-21

Family

ID=40951496

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013305A MX2009013305A (es) 2007-06-06 2008-06-04 Composicion farmaceutica de un nuevo sistema para liberacion vaginal de esteroides.

Country Status (9)

Country Link
EP (1) EP2157946A1 (es)
CN (1) CN101730514A (es)
AR (1) AR070302A1 (es)
BR (1) BRPI0812578A2 (es)
CA (1) CA2689987A1 (es)
CO (1) CO6270199A2 (es)
MX (1) MX2009013305A (es)
PE (1) PE20090324A1 (es)
WO (1) WO2008154240A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011073995A2 (en) 2009-12-14 2011-06-23 Lincoln Pharmaceuticals Limited Liquid vaginal spray of progesterone
CA2930533A1 (en) * 2013-11-12 2015-05-21 University Of Utah Research Foundation Glycol chitin based thermosensitive hydrogel for vaginal delivery of progesterone
CN114129530A (zh) * 2021-12-08 2022-03-04 南京康川济医药科技有限公司 一种黄体酮缓释组合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997040792A1 (en) * 1996-04-30 1997-11-06 Theratech, Inc. Transdermal administration of steroid hormones using diethanolamides of c12-c18 fatty acids as permeation enhancers
ITMI20010913A1 (it) * 2001-05-04 2002-11-04 Univ Pavia Composizioni a rilascio controllato di acido lattico a livello vaginale

Also Published As

Publication number Publication date
CO6270199A2 (es) 2011-04-20
CA2689987A1 (en) 2008-12-18
WO2008154240A1 (en) 2008-12-18
CN101730514A (zh) 2010-06-09
EP2157946A1 (en) 2010-03-03
BRPI0812578A2 (pt) 2015-09-29
PE20090324A1 (es) 2009-04-09
AR070302A1 (es) 2010-03-31

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal