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MX2009013123A - Composiciones y metodos para modular la inflamacion usando fluoroquinolonas. - Google Patents

Composiciones y metodos para modular la inflamacion usando fluoroquinolonas.

Info

Publication number
MX2009013123A
MX2009013123A MX2009013123A MX2009013123A MX2009013123A MX 2009013123 A MX2009013123 A MX 2009013123A MX 2009013123 A MX2009013123 A MX 2009013123A MX 2009013123 A MX2009013123 A MX 2009013123A MX 2009013123 A MX2009013123 A MX 2009013123A
Authority
MX
Mexico
Prior art keywords
compositions
methods
inflammation
modulating
fluoroquinolones
Prior art date
Application number
MX2009013123A
Other languages
English (en)
Inventor
Keith Wayne Ward
Jinzhong Zhang
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Publication of MX2009013123A publication Critical patent/MX2009013123A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composiciones para modular una inflamación que comprenden una fluoroquinolona que tiene una de la Fórmula I -VIII. Los métodos para modular una inflamación comprenden administrar las composiciones a un sujeto en necesidad de la misma. Las composiciones y métodos son apropiados para modular una inflamación ocular u oftálmica, incluyendo uveítis, queratoconjuntivitis primaveral, o inflamación asociada con infiltrados corneales asociados al uso de lentes de contacto.
MX2009013123A 2007-06-11 2008-05-21 Composiciones y metodos para modular la inflamacion usando fluoroquinolonas. MX2009013123A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94315407P 2007-06-11 2007-06-11
PCT/US2008/064336 WO2008154136A1 (en) 2007-06-11 2008-05-21 Compositions and methods for modulating inflammation using fluoroquinolones

Publications (1)

Publication Number Publication Date
MX2009013123A true MX2009013123A (es) 2010-01-15

Family

ID=39673477

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013123A MX2009013123A (es) 2007-06-11 2008-05-21 Composiciones y metodos para modular la inflamacion usando fluoroquinolonas.

Country Status (11)

Country Link
US (1) US20080306038A1 (es)
EP (1) EP2170342A1 (es)
JP (1) JP2010529133A (es)
KR (1) KR20100021444A (es)
CN (1) CN101678032A (es)
AU (1) AU2008262118A1 (es)
BR (1) BRPI0811223A2 (es)
CA (1) CA2686833A1 (es)
MX (1) MX2009013123A (es)
TW (1) TW200904429A (es)
WO (1) WO2008154136A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2402321T3 (es) * 2007-11-05 2013-04-30 Bausch & Lomb Incorporated Materiales inmiscibles en agua como vehículos para el suministro de fármacos
CN102114020B (zh) * 2009-12-30 2016-04-20 北京德众万全医药科技有限公司 一种含有贝西沙星或其盐的药用组合物及其制备方法
AU2015212312A1 (en) 2014-01-29 2016-08-18 Vyome Therapeutics Limited Treatments for resistant acne
CN119587555B (zh) * 2024-12-17 2025-12-19 江汉大学 依碳氯替泼诺作为nlrp3炎症小体激活抑制剂的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2613139B2 (ja) * 1990-07-19 1997-05-21 エスエス製薬 株式会社 キノロンカルボン酸誘導体
US6685958B2 (en) * 2001-04-25 2004-02-03 Insite Vision Incorporated Quinolone carboxylic acid compositions and related methods of treatment
US20030105073A1 (en) * 2001-10-23 2003-06-05 Haughan Alan Findlay Quinolone derivatives
JP2006525011A (ja) * 2003-04-30 2006-11-09 ファイザー・プロダクツ・インク 白内障形成リスクに関するスクリーニング法

Also Published As

Publication number Publication date
US20080306038A1 (en) 2008-12-11
EP2170342A1 (en) 2010-04-07
CA2686833A1 (en) 2008-12-18
BRPI0811223A2 (pt) 2014-10-29
WO2008154136A1 (en) 2008-12-18
KR20100021444A (ko) 2010-02-24
JP2010529133A (ja) 2010-08-26
CN101678032A (zh) 2010-03-24
AU2008262118A1 (en) 2008-12-18
TW200904429A (en) 2009-02-01

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal