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MX2009011851A - Plasmidos de dna que tienen expresion y estabilidad mejoradas. - Google Patents

Plasmidos de dna que tienen expresion y estabilidad mejoradas.

Info

Publication number
MX2009011851A
MX2009011851A MX2009011851A MX2009011851A MX2009011851A MX 2009011851 A MX2009011851 A MX 2009011851A MX 2009011851 A MX2009011851 A MX 2009011851A MX 2009011851 A MX2009011851 A MX 2009011851A MX 2009011851 A MX2009011851 A MX 2009011851A
Authority
MX
Mexico
Prior art keywords
stability
dna plasmids
improved expression
compositions
present
Prior art date
Application number
MX2009011851A
Other languages
English (en)
Inventor
Jean-Christophe Audonnet
Original Assignee
Merial Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd filed Critical Merial Ltd
Publication of MX2009011851A publication Critical patent/MX2009011851A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se relaciona a composiciones y métodos para mejorar la expresión de polipéptidos exógenos, tal como un antígeno, epítope, inmunógeno, péptido o polipéptido de interés. Más particularmente, la presente invención proporciona plásmidos de DNA con expresión y estabilidad incrementadas en composiciones y métodos útiles para vacunas de DNA.
MX2009011851A 2007-05-02 2007-05-02 Plasmidos de dna que tienen expresion y estabilidad mejoradas. MX2009011851A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/010547 WO2008136790A1 (en) 2007-05-02 2007-05-02 Dna plasmids having improved expression and stability

Publications (1)

Publication Number Publication Date
MX2009011851A true MX2009011851A (es) 2010-03-04

Family

ID=38728755

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011851A MX2009011851A (es) 2007-05-02 2007-05-02 Plasmidos de dna que tienen expresion y estabilidad mejoradas.

Country Status (14)

Country Link
EP (1) EP2147105B1 (es)
JP (1) JP2010525812A (es)
KR (1) KR101445903B1 (es)
CN (1) CN102016045A (es)
AU (1) AU2007352618B2 (es)
BR (1) BRPI0721630A2 (es)
CA (1) CA2684923C (es)
DK (1) DK2147105T3 (es)
HR (1) HRP20130643T1 (es)
IN (1) IN2009DN07240A (es)
MX (1) MX2009011851A (es)
SI (1) SI2147105T1 (es)
UA (1) UA100692C2 (es)
WO (1) WO2008136790A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9045759B2 (en) 2009-01-21 2015-06-02 James Arthur Williams DNA plasmids with improved copy number
CN104726505A (zh) * 2015-03-31 2015-06-24 上海交通大学 一种利用基因工程蓝藻生产三碳化合物的方法
CN118638209A (zh) * 2024-06-20 2024-09-13 上海唯科生物制药有限公司 一种重组肿瘤坏死因子的生产方法

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CA2684923A1 (en) 2008-11-13
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BRPI0721630A2 (pt) 2013-10-15
JP2010525812A (ja) 2010-07-29
IN2009DN07240A (es) 2015-07-24
CA2684923C (en) 2015-01-06
AU2007352618B2 (en) 2013-07-18
CN102016045A (zh) 2011-04-13
KR20100017558A (ko) 2010-02-16
KR101445903B1 (ko) 2014-09-29
AU2007352618A1 (en) 2008-11-13
UA100692C2 (ru) 2013-01-25
SI2147105T1 (sl) 2013-08-30
DK2147105T3 (da) 2013-06-03
EP2147105A1 (en) 2010-01-27
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