MX2009010763A - NUEVO REGIMEN DE DROSPIRENONA/17ß-ESTRADIOL, PRODUCTO FARMACEUTICO COMBINADO Y CONJUNTO DE ELEMENTOS (KIT) PARA SU APLICACION. - Google Patents
NUEVO REGIMEN DE DROSPIRENONA/17ß-ESTRADIOL, PRODUCTO FARMACEUTICO COMBINADO Y CONJUNTO DE ELEMENTOS (KIT) PARA SU APLICACION.Info
- Publication number
- MX2009010763A MX2009010763A MX2009010763A MX2009010763A MX2009010763A MX 2009010763 A MX2009010763 A MX 2009010763A MX 2009010763 A MX2009010763 A MX 2009010763A MX 2009010763 A MX2009010763 A MX 2009010763A MX 2009010763 A MX2009010763 A MX 2009010763A
- Authority
- MX
- Mexico
- Prior art keywords
- drospirenone
- regimen
- pharmaceutical combination
- estradiol
- combination product
- Prior art date
Links
- METQSPRSQINEEU-UHFFFAOYSA-N dihydrospirorenone Natural products CC12CCC(C3(CCC(=O)C=C3C3CC33)C)C3C1C1CC1C21CCC(=O)O1 METQSPRSQINEEU-UHFFFAOYSA-N 0.000 title abstract 5
- METQSPRSQINEEU-HXCATZOESA-N drospirenone Chemical compound C([C@]12[C@H]3C[C@H]3[C@H]3[C@H]4[C@@H]([C@]5(CCC(=O)C=C5[C@@H]5C[C@@H]54)C)CC[C@@]31C)CC(=O)O2 METQSPRSQINEEU-HXCATZOESA-N 0.000 title abstract 5
- 229960004845 drospirenone Drugs 0.000 title abstract 5
- 239000013066 combination product Substances 0.000 title abstract 2
- 229940127555 combination product Drugs 0.000 title abstract 2
- 229960005309 estradiol Drugs 0.000 title abstract 2
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title 2
- 206010047998 Withdrawal bleed Diseases 0.000 abstract 1
- 238000012423 maintenance Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se relaciona con un producto farmacéutico combinado de al menos 21 unidades de dosificación diarias consecutivas que contienen entre 2,0 mg y 3,0 mg de drospirenona y entre 1,0 y 2,0 mg de 17ß-estradiol en cada unidad de dosificación diaria seguido por unidades de dosificación diarias intermitentes que contienen la misma cantidad, o una cantidad menor, de drospirenona (es decir, entre 0,5 mg y 3,0 mg) como unidades de dosificación diarias consecutivas, en donde cada unidad de dosificación diaria intermitente está precedida por al menos un día sin administración de drospirenona. Estos productos farmacéuticos combinados se pueden usar en la contracepción oral femenina, pueden asegurar un sangrado por deprivación cada 4 semanas y permitir el mantenimiento completo de los beneficios relacionados con la drospirenona.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91032607P | 2007-04-05 | 2007-04-05 | |
| US3528508P | 2008-03-10 | 2008-03-10 | |
| US4049408P | 2008-03-28 | 2008-03-28 | |
| PCT/EP2008/002823 WO2008122439A2 (en) | 2007-04-05 | 2008-04-07 | Dr0spiren0ne/17beta-estradi0l regimen, pharmaceutical combination product and kit for performing this regimen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009010763A true MX2009010763A (es) | 2009-10-28 |
Family
ID=39745001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009010763A MX2009010763A (es) | 2007-04-05 | 2008-04-07 | NUEVO REGIMEN DE DROSPIRENONA/17ß-ESTRADIOL, PRODUCTO FARMACEUTICO COMBINADO Y CONJUNTO DE ELEMENTOS (KIT) PARA SU APLICACION. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20090023693A1 (es) |
| EP (1) | EP2150257A2 (es) |
| JP (1) | JP2010523512A (es) |
| CN (1) | CN101674837A (es) |
| AR (1) | AR065971A1 (es) |
| AU (1) | AU2008235006A1 (es) |
| BR (1) | BRPI0810049A2 (es) |
| CA (1) | CA2683093A1 (es) |
| CL (1) | CL2008000999A1 (es) |
| IL (1) | IL201302A0 (es) |
| MX (1) | MX2009010763A (es) |
| PE (1) | PE20090805A1 (es) |
| TW (1) | TW200904452A (es) |
| UY (1) | UY31010A1 (es) |
| WO (1) | WO2008122439A2 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8617597B2 (en) | 2006-07-06 | 2013-12-31 | Bayer Intellectual Property Gmbh | Pharmaceutical composition containing a tetrahydrofolic acid |
| DK2419108T3 (en) | 2009-04-14 | 2016-12-05 | Hra Pharma Lab | A method for on-demand control of conception, |
| JP5852639B2 (ja) * | 2010-04-15 | 2016-02-03 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | Ｈｒｔのための低用量固体経口投与形態 |
| CN102985070A (zh) * | 2010-04-15 | 2013-03-20 | 拜耳知识产权有限责任公司 | 用于hrt的极低剂量的固体口服剂型 |
| CA2989975C (en) * | 2015-06-23 | 2021-10-12 | Laboratorios Leon Farma Sa | Drospirenone-based contraceptive for a female patient affected with excess weight |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101019361B1 (ko) * | 1999-08-31 | 2011-03-07 | 바이엘 쉐링 파마 악티엔게젤샤프트 | 피임약으로서의 사용을 위한 에티닐에스트라디올과드로스피렌온의 약학적 조합 |
| US20020132801A1 (en) * | 2001-01-11 | 2002-09-19 | Schering Aktiengesellschaft | Drospirenone for hormone replacement therapy |
| UY29527A1 (es) * | 2005-05-13 | 2006-12-29 | Schering Ag | Composicinn farmaccutica que contienen gestrgenos y/o estrngenos y 5-metil - (6s) - tetrhidrofolato. |
-
2008
- 2008-04-07 AU AU2008235006A patent/AU2008235006A1/en not_active Abandoned
- 2008-04-07 AR ARP080101436A patent/AR065971A1/es unknown
- 2008-04-07 TW TW097112528A patent/TW200904452A/zh unknown
- 2008-04-07 JP JP2010501448A patent/JP2010523512A/ja active Pending
- 2008-04-07 EP EP08735133A patent/EP2150257A2/en not_active Withdrawn
- 2008-04-07 CL CL200800999A patent/CL2008000999A1/es unknown
- 2008-04-07 MX MX2009010763A patent/MX2009010763A/es unknown
- 2008-04-07 CA CA002683093A patent/CA2683093A1/en not_active Abandoned
- 2008-04-07 BR BRPI0810049 patent/BRPI0810049A2/pt not_active IP Right Cessation
- 2008-04-07 WO PCT/EP2008/002823 patent/WO2008122439A2/en not_active Ceased
- 2008-04-07 UY UY31010A patent/UY31010A1/es not_active Application Discontinuation
- 2008-04-07 PE PE2008000621A patent/PE20090805A1/es not_active Application Discontinuation
- 2008-04-07 US US12/098,831 patent/US20090023693A1/en not_active Abandoned
- 2008-04-07 CN CN200880014865A patent/CN101674837A/zh active Pending
-
2009
- 2009-10-01 IL IL201302A patent/IL201302A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR065971A1 (es) | 2009-07-15 |
| BRPI0810049A2 (pt) | 2015-05-05 |
| UY31010A1 (es) | 2008-11-28 |
| IL201302A0 (en) | 2010-05-31 |
| CN101674837A (zh) | 2010-03-17 |
| US20090023693A1 (en) | 2009-01-22 |
| CL2008000999A1 (es) | 2008-10-10 |
| TW200904452A (en) | 2009-02-01 |
| JP2010523512A (ja) | 2010-07-15 |
| CA2683093A1 (en) | 2008-10-16 |
| WO2008122439A3 (en) | 2009-07-23 |
| EP2150257A2 (en) | 2010-02-10 |
| WO2008122439A2 (en) | 2008-10-16 |
| PE20090805A1 (es) | 2009-07-25 |
| AU2008235006A1 (en) | 2008-10-16 |
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