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MX2009010059A - Derivados de quinolina para el tratamiento de enfermedades inflamatorias. - Google Patents

Derivados de quinolina para el tratamiento de enfermedades inflamatorias.

Info

Publication number
MX2009010059A
MX2009010059A MX2009010059A MX2009010059A MX2009010059A MX 2009010059 A MX2009010059 A MX 2009010059A MX 2009010059 A MX2009010059 A MX 2009010059A MX 2009010059 A MX2009010059 A MX 2009010059A MX 2009010059 A MX2009010059 A MX 2009010059A
Authority
MX
Mexico
Prior art keywords
treatment
inflammatory diseases
quinoline derivatives
pharmaceutical compositions
quinoline
Prior art date
Application number
MX2009010059A
Other languages
English (en)
Inventor
Simon David Guile
Mark Ebden
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2009010059A publication Critical patent/MX2009010059A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
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Abstract

La presente invención se refiere a compuestos de fórmula (I), procesos para su preparación, composiciones farmacéuticas que los contienen, un proceso para preparar las composiciones farmacéuticas, y su uso en terapia, en donde R1, R2, R3 y n son como se definen en la especificación.
MX2009010059A 2007-03-22 2008-03-19 Derivados de quinolina para el tratamiento de enfermedades inflamatorias. MX2009010059A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89629807P 2007-03-22 2007-03-22
PCT/GB2008/000946 WO2008114002A1 (en) 2007-03-22 2008-03-19 Quinoline derivatives for the treatment of inflammatory diseases

Publications (1)

Publication Number Publication Date
MX2009010059A true MX2009010059A (es) 2009-10-12

Family

ID=39471999

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009010059A MX2009010059A (es) 2007-03-22 2008-03-19 Derivados de quinolina para el tratamiento de enfermedades inflamatorias.

Country Status (17)

Country Link
US (1) US7964616B2 (es)
EP (1) EP2139879B1 (es)
JP (1) JP2010522227A (es)
KR (1) KR20090122396A (es)
CN (1) CN101679350B (es)
AR (1) AR065806A1 (es)
AU (1) AU2008228067B2 (es)
BR (1) BRPI0809106A2 (es)
CA (1) CA2680761A1 (es)
CL (1) CL2008000825A1 (es)
ES (1) ES2388454T3 (es)
MX (1) MX2009010059A (es)
PE (1) PE20091225A1 (es)
RU (1) RU2460727C2 (es)
TW (1) TW200904427A (es)
UY (1) UY30976A1 (es)
WO (1) WO2008114002A1 (es)

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US20180179179A1 (en) 2016-12-22 2018-06-28 Incyte Corporation Heterocyclic compounds as immunomodulators
IL295660A (en) 2016-12-22 2022-10-01 Incyte Corp Benzooxazole derivatives as immunomodulators
KR20250067967A (ko) 2018-03-30 2025-05-15 인사이트 코포레이션 면역조절제로서 복소환형 화합물
HUE061503T2 (hu) 2018-05-11 2023-07-28 Incyte Corp Tetrahidro-imidazo[4,5-C]piridin-származékok mint PD-L1 immunmodulátorok
EP3962493A2 (en) 2019-05-03 2022-03-09 Flagship Pioneering Innovations V, Inc. Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor
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CN101679350A (zh) 2010-03-24
RU2460727C2 (ru) 2012-09-10
HK1138850A1 (en) 2010-09-03
EP2139879B1 (en) 2012-07-11
AU2008228067B2 (en) 2011-12-08
RU2009135621A (ru) 2011-04-27
TW200904427A (en) 2009-02-01
PE20091225A1 (es) 2009-09-16
UY30976A1 (es) 2008-10-31
US20080234319A1 (en) 2008-09-25
KR20090122396A (ko) 2009-11-27
AU2008228067A1 (en) 2008-09-25
CN101679350B (zh) 2014-03-12
WO2008114002A1 (en) 2008-09-25
EP2139879A1 (en) 2010-01-06
JP2010522227A (ja) 2010-07-01
CA2680761A1 (en) 2008-09-25
ES2388454T3 (es) 2012-10-15
CL2008000825A1 (es) 2008-11-03
US7964616B2 (en) 2011-06-21
BRPI0809106A2 (pt) 2014-08-26
AR065806A1 (es) 2009-07-01

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