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MX2009009849A - Derivados de piridazinona sustituida con piperazina utiles como inhibidores de glucano sintasa. - Google Patents

Derivados de piridazinona sustituida con piperazina utiles como inhibidores de glucano sintasa.

Info

Publication number
MX2009009849A
MX2009009849A MX2009009849A MX2009009849A MX2009009849A MX 2009009849 A MX2009009849 A MX 2009009849A MX 2009009849 A MX2009009849 A MX 2009009849A MX 2009009849 A MX2009009849 A MX 2009009849A MX 2009009849 A MX2009009849 A MX 2009009849A
Authority
MX
Mexico
Prior art keywords
glucan synthase
piperazine
synthase inhibitors
derivatives useful
administration
Prior art date
Application number
MX2009009849A
Other languages
English (en)
Inventor
Pauline C Ting
Todd A Black
Paul M Mcnicholas
Scott S Walker
Yiming Xu
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MX2009009849A publication Critical patent/MX2009009849A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/58—1,2-Diazines; Hydrogenated 1,2-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Agronomy & Crop Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Se describe un método para el tratamiento o prevención de infecciones fúngicas que comprende la administración de al menos un inhibidor de glucano sintasa de una fórmula como la descrita anteriormente en la especificación o una sal farmacéuticamente aceptable del mismo; también se reclaman métodos de preparación de composiciones farmacéuticas que comprenden un compuesto como el descrito anteriormente en la especificación y un portador, método de tratamiento o prevención de infecciones fúngicas que comprende la administración de combinaciones de inhibidor de glucano sintasa de una fórmula como la descrita anteriormente en la especificación y otros agentes anti-fúngicos, y método de tratamiento o prevención de infecciones fúngicas que comprende la administración de composiciones farmacéuticas preparadas de acuerdo a un método descrito anteriormente en la especificación, y un métodos para la preparación de un equipo en un paquete sencillo de la composición farmacéutica descrita anteriormente y otros agentes anti-fúngicos.
MX2009009849A 2007-03-15 2008-03-12 Derivados de piridazinona sustituida con piperazina utiles como inhibidores de glucano sintasa. MX2009009849A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91818207P 2007-03-15 2007-03-15
PCT/US2008/003292 WO2008115385A2 (en) 2007-03-15 2008-03-12 Piperazine-substituted pyridazinone derivatives useful as glucan synthase inhibitors

Publications (1)

Publication Number Publication Date
MX2009009849A true MX2009009849A (es) 2009-09-24

Family

ID=39712325

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009009849A MX2009009849A (es) 2007-03-15 2008-03-12 Derivados de piridazinona sustituida con piperazina utiles como inhibidores de glucano sintasa.

Country Status (7)

Country Link
US (1) US20100158992A1 (es)
EP (1) EP2136808A2 (es)
JP (1) JP2010521463A (es)
CN (1) CN101668529A (es)
CA (1) CA2680587A1 (es)
MX (1) MX2009009849A (es)
WO (1) WO2008115385A2 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2008000725A1 (es) * 2007-03-15 2008-11-14 Schering Corp Compuestos derivados de heterociclos aromaticos; composicion farmaceutica; kit farmceuticos; uso de la composicion y de los compuestos como inhibidores de glucano sintasa para el tratamiento o prevencion del crecimiento de patogenos fungicos en planta y para tratar o prevenir infecciones producidas por hongos.
WO2011028492A2 (en) * 2009-08-24 2011-03-10 The Regents Of The University Of California Sortase a inhibitors
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
US9585396B2 (en) 2013-01-30 2017-03-07 Agrofresh Inc. Volatile applications against pathogens
AU2014212576B2 (en) 2013-01-30 2015-08-13 Agrofresh Inc. Use of benzoxaboroles as volatile antimicrobial agents on meats, plants, or plant parts
US8669207B1 (en) 2013-01-30 2014-03-11 Dow Agrosciences, Llc. Compounds and compositions
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
ES2886766T3 (es) 2015-03-31 2021-12-20 Enanta Pharm Inc Derivados del ácido biliar como agonistas de FXR/TGR5 y métodos de uso de estos
CN105112304B (zh) * 2015-09-08 2018-01-02 湖北省农业科学院植保土肥研究所 一种防治蔬菜根部病害的多孔烟管菌高氏15号及其制剂
NZ745681A (en) 2016-03-07 2022-05-27 Agrofresh Inc Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops
JP2019537557A (ja) 2016-10-04 2019-12-26 エナンタ ファーマシューティカルズ インコーポレイテッド Ｆｘｒアゴニストとしてのイソキサゾール類似体およびその使用方法
AU2018334290A1 (en) 2017-09-18 2020-04-02 Goldfinch Bio, Inc. Pyridazinones and methods of use thereof
TWI894724B (zh) 2018-09-18 2025-08-21 美商金翅雀生技公司 噠嗪酮及其使用方法
US11555032B2 (en) 2019-05-13 2023-01-17 Enanta Pharmaceuticals, Inc. Isoxazole derivatives as FXR agonists and methods of use thereof
WO2023204124A1 (ja) * 2022-04-20 2023-10-26 日本曹達株式会社 ピリダジノン化合物並びに農園芸用殺菌剤、殺線虫剤、および医療用・動物用抗真菌剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5826802A (ja) * 1981-08-10 1983-02-17 Sankyo Co Ltd 農園芸用殺菌剤
JPS5826803A (ja) * 1981-08-10 1983-02-17 Sankyo Co Ltd 農園芸用殺菌剤
CN1633434A (zh) * 2002-01-31 2005-06-29 第一制药株式会社 咪唑并[1,2－a]吡啶衍生物
DE10216144A1 (de) * 2002-04-12 2003-11-06 Bayer Ag Substituierte 2-Phenyl-3(2H)-Pyridazinone
CL2008000725A1 (es) * 2007-03-15 2008-11-14 Schering Corp Compuestos derivados de heterociclos aromaticos; composicion farmaceutica; kit farmceuticos; uso de la composicion y de los compuestos como inhibidores de glucano sintasa para el tratamiento o prevencion del crecimiento de patogenos fungicos en planta y para tratar o prevenir infecciones producidas por hongos.

Also Published As

Publication number Publication date
JP2010521463A (ja) 2010-06-24
CA2680587A1 (en) 2008-09-25
WO2008115385A3 (en) 2009-01-08
CN101668529A (zh) 2010-03-10
EP2136808A2 (en) 2009-12-30
WO2008115385A2 (en) 2008-09-25
US20100158992A1 (en) 2010-06-24

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