MX2009009370A - Conjugados del complemento de peptido. - Google Patents
Conjugados del complemento de peptido.Info
- Publication number
- MX2009009370A MX2009009370A MX2009009370A MX2009009370A MX2009009370A MX 2009009370 A MX2009009370 A MX 2009009370A MX 2009009370 A MX2009009370 A MX 2009009370A MX 2009009370 A MX2009009370 A MX 2009009370A MX 2009009370 A MX2009009370 A MX 2009009370A
- Authority
- MX
- Mexico
- Prior art keywords
- peptide
- conjugates
- complement
- complement conjugates
- group
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 239000012634 fragment Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/472—Complement proteins, e.g. anaphylatoxin, C3a, C5a
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
- C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
- C07K14/16—HIV-1 ; HIV-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- AIDS & HIV (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención informa sobre un conjugado de polipéptidos, donde el conjugado comprende un primer polipéptido seleccionado del grupo de polipéptidos que comprenden SEC ID NO: 01 y fragmentos del mismo, y un segundo polipéptido seleccionado del grupo de péptidos antifusogénicos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07005096 | 2007-03-13 | ||
| PCT/EP2008/001908 WO2008110332A1 (en) | 2007-03-13 | 2008-03-11 | Peptide-complement conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009009370A true MX2009009370A (es) | 2009-09-14 |
Family
ID=37998311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009009370A MX2009009370A (es) | 2007-03-13 | 2008-03-11 | Conjugados del complemento de peptido. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20090143288A1 (es) |
| EP (1) | EP2118125B1 (es) |
| JP (1) | JP5081931B2 (es) |
| KR (1) | KR101182951B1 (es) |
| CN (1) | CN101616929B (es) |
| AR (1) | AR065688A1 (es) |
| AT (1) | ATE530564T1 (es) |
| AU (1) | AU2008226051B2 (es) |
| BR (1) | BRPI0808732A2 (es) |
| CA (1) | CA2679647A1 (es) |
| CL (1) | CL2008000707A1 (es) |
| ES (1) | ES2374962T3 (es) |
| IL (1) | IL199718A0 (es) |
| MX (1) | MX2009009370A (es) |
| PE (1) | PE20090163A1 (es) |
| TW (1) | TW200902544A (es) |
| WO (1) | WO2008110332A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3255146B1 (en) | 2009-03-16 | 2019-05-15 | Pangu Biopharma Limited | Compositions and methods comprising histidyl-trna synthetase splice variants having non-canonical biological activities |
| GB0913385D0 (en) | 2009-07-31 | 2009-09-16 | Medical House The Plc | Improved autoinjector |
| BR112013002292A2 (pt) * | 2010-09-14 | 2016-06-14 | Hoffmann La Roche | polipeptídeo du fusão, complexo de proteína, uso e kit |
| JP6397479B2 (ja) * | 2013-03-15 | 2018-09-26 | エータイアー ファーマ, インコーポレイテッド | ヒスチジル−tRNAシンテターゼFcコンジュゲート |
| JP7235676B2 (ja) * | 2017-05-17 | 2023-03-08 | ザ ジェネラル ホスピタル コーポレイション | 結節性硬化症の遺伝子治療 |
Family Cites Families (48)
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| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| JP3150340B2 (ja) | 1990-11-13 | 2001-03-26 | イムネクス コーポレイション | 二機能選択可能融合遺伝子 |
| DE69126301T2 (de) | 1990-11-27 | 1998-01-02 | Biogen, Inc., Cambridge, Mass. | Hiv-induzierte synzytien blockierender anti-cd-4-antikörper |
| US6136310A (en) * | 1991-07-25 | 2000-10-24 | Idec Pharmaceuticals Corporation | Recombinant anti-CD4 antibodies for human therapy |
| DK1266965T3 (da) | 1991-07-25 | 2006-09-25 | Biogen Idec Inc | Rekombinante antistoffer til human terapi |
| DE69326069T2 (de) * | 1992-07-20 | 2000-03-23 | Duke University, Durham | Zusammensetzungen die die hiv replikation inhibieren |
| CA2163427A1 (en) | 1993-05-21 | 1994-12-08 | Stephen D. Lupton | Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene |
| US6017536A (en) * | 1993-06-07 | 2000-01-25 | Trimeris, Inc. | Simian immunodeficiency virus peptides with antifusogenic and antiviral activities |
| US5464933A (en) | 1993-06-07 | 1995-11-07 | Duke University | Synthetic peptide inhibitors of HIV transmission |
| US6479055B1 (en) | 1993-06-07 | 2002-11-12 | Trimeris, Inc. | Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission |
| WO1996036359A1 (en) | 1995-05-18 | 1996-11-21 | Ortho Pharmaceutical Corporation | Induction of immunological tolerance by the use of non-depleting anti-cd4 antibodies |
| US6743594B1 (en) * | 1995-06-06 | 2004-06-01 | Human Genome Sciences, Inc. | Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5) |
| JPH11507632A (ja) | 1995-06-07 | 1999-07-06 | トリメリス,インコーポレーテッド | 併用療法を用いたhivおよび他のウイルス感染の治療 |
| AU3375697A (en) * | 1996-05-28 | 1998-01-05 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Cc chemokine receptor 5, antibodies thereto, transgenic animals |
| DK0910659T3 (da) | 1996-06-03 | 2006-11-27 | United Biomedical Inc | Antistoffer mod et kompleks af CD4 og et kemokin-receptordomæne og anvendelse deraf mod HIV-infektioner |
| US6020159A (en) | 1996-09-24 | 2000-02-01 | Smithkline Beecham Corporation | 3-dehydroquinate synthase |
| US6528625B1 (en) * | 1996-10-28 | 2003-03-04 | Millennium Pharmaceuticals, Inc. | Anti-CCR5 antibodies and kits comprising same |
| US5888809A (en) * | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
| US6020495A (en) * | 1997-12-08 | 2000-02-01 | Pharm-Eco Laboratories, Inc. | Stereoselective method for synthesizing dolaphenine |
| US6656906B1 (en) * | 1998-05-20 | 2003-12-02 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
| US6258782B1 (en) * | 1998-05-20 | 2001-07-10 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
| US20030099645A1 (en) * | 2000-10-10 | 2003-05-29 | Lobo Peter Isaac | Naturally occuring IgM antibodies that bind to membrane receptors on lymphocytes |
| US6610834B1 (en) * | 1998-11-18 | 2003-08-26 | Peter I. Lobo | Human IgM antibodies to chemokine receptors |
| CA2355607A1 (en) | 1998-12-16 | 2000-06-22 | Progenics Pharmaceuticals, Inc. | Anti-ccr5 antibody |
| WO2000053633A2 (de) | 1999-03-11 | 2000-09-14 | Micromet Ag | Antikörper- und chemokinkonstrukte, die gegen ccr5 gerichtet sind, und ihre verwendung in der behandlung von autoimmunkrankheiten |
| DK1264840T3 (da) * | 1999-05-17 | 2009-11-16 | Conjuchem Biotechnologies Inc | Langtidsvirkende fusionspeptidinhibitorer af viral infektion |
| WO2001042308A2 (en) | 1999-12-08 | 2001-06-14 | Novartis Ag | Methods and compositions useful for inhibiting ccr5-dependent infection of cells by hiv-1 |
| AU2265701A (en) | 1999-12-16 | 2001-06-25 | Tanox, Inc. | Anti-hiv-1 conjugates for treatment of hiv disease |
| US6692745B2 (en) * | 2000-01-28 | 2004-02-17 | Arogenics Pharmaceuticals, Inc. | Compositions and methods for inhibition of HIV-1 infection |
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| US7005503B2 (en) * | 2002-02-08 | 2006-02-28 | Genetastix Corporation | Human monoclonal antibody against coreceptors for human immunodeficiency virus |
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| EP1207202A1 (en) | 2000-11-16 | 2002-05-22 | Mölling, Karin, Inst. für med. Virologie der Uni. Zürich | Nucleic acid molecules encoding a protein interacting with the chemokine receptor CCR5 or other chemokine receptor family members |
| US20020147147A1 (en) * | 2000-11-16 | 2002-10-10 | Karin Molling | Nucleic acid molecules encoding a protein interacting with the chemokine receptor CCR5 or other chemokine receptor family members |
| US7175988B2 (en) * | 2001-02-09 | 2007-02-13 | Human Genome Sciences, Inc. | Human G-protein Chemokine Receptor (CCR5) HDGNR10 |
| US20030003440A1 (en) * | 2001-03-14 | 2003-01-02 | Lucia Lopalco | Novel CCR5 epitope and antibodies against it |
| US20020146415A1 (en) * | 2001-04-06 | 2002-10-10 | Olson William C. | Methods for inhibiting HIV-1 infection |
| US7060273B2 (en) * | 2001-04-06 | 2006-06-13 | Progenics Pharmaceuticals, Inc. | Methods for inhibiting HIV-1 infection |
| CN1255548C (zh) | 2001-06-15 | 2006-05-10 | 霍夫曼-拉罗奇有限公司 | gp41片段的乙酰化 |
| AU2002337885B1 (en) | 2001-10-16 | 2003-04-28 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Broadly cross-reactive neutralizing antibodies against human ummunodeficiency virus selected by Env-CD4-co-receptor complexes |
| AU2003209059A1 (en) | 2002-02-08 | 2003-09-02 | Genetastix Corporation | Human monoclonal antibodies against membrane proteins |
| EP1478738B1 (en) | 2002-02-22 | 2008-11-12 | Progenics Pharmaceuticals, Inc. | Anti-ccr5 antibody |
| US7122185B2 (en) * | 2002-02-22 | 2006-10-17 | Progenics Pharmaceuticals, Inc. | Anti-CCR5 antibody |
| EP1460088A1 (en) * | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
| BRPI0418304A (pt) * | 2004-01-07 | 2007-05-02 | Trimeris Inc | peptìdeo sintético, uso do mesmo, composição farmacêutica, seqüência de nucleotìdeos, e, métodos para inibição da transmissão de hiv para uma célula, para inibição da fusão de hiv, e para tratamento de um indivìduo infectado com hiv |
| TW200720289A (en) | 2005-04-01 | 2007-06-01 | Hoffmann La Roche | Antibodies against CCR5 and uses thereof |
-
2008
- 2008-03-10 CL CL200800707A patent/CL2008000707A1/es unknown
- 2008-03-10 TW TW097108371A patent/TW200902544A/zh unknown
- 2008-03-10 US US12/075,183 patent/US20090143288A1/en not_active Abandoned
- 2008-03-11 AR ARP080100996A patent/AR065688A1/es unknown
- 2008-03-11 CA CA002679647A patent/CA2679647A1/en not_active Abandoned
- 2008-03-11 JP JP2009552135A patent/JP5081931B2/ja not_active Expired - Fee Related
- 2008-03-11 EP EP08716417A patent/EP2118125B1/en not_active Not-in-force
- 2008-03-11 AT AT08716417T patent/ATE530564T1/de active
- 2008-03-11 KR KR1020097018750A patent/KR101182951B1/ko not_active Expired - Fee Related
- 2008-03-11 ES ES08716417T patent/ES2374962T3/es active Active
- 2008-03-11 MX MX2009009370A patent/MX2009009370A/es active IP Right Grant
- 2008-03-11 CN CN2008800052530A patent/CN101616929B/zh not_active Expired - Fee Related
- 2008-03-11 AU AU2008226051A patent/AU2008226051B2/en not_active Ceased
- 2008-03-11 BR BRPI0808732-6A patent/BRPI0808732A2/pt not_active IP Right Cessation
- 2008-03-11 WO PCT/EP2008/001908 patent/WO2008110332A1/en not_active Ceased
- 2008-03-12 PE PE2008000470A patent/PE20090163A1/es not_active Application Discontinuation
-
2009
- 2009-07-07 IL IL199718A patent/IL199718A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20090115867A (ko) | 2009-11-09 |
| US20090143288A1 (en) | 2009-06-04 |
| CN101616929B (zh) | 2013-08-14 |
| PE20090163A1 (es) | 2009-03-12 |
| JP2010520868A (ja) | 2010-06-17 |
| EP2118125B1 (en) | 2011-10-26 |
| ATE530564T1 (de) | 2011-11-15 |
| AU2008226051B2 (en) | 2012-05-24 |
| IL199718A0 (en) | 2010-04-15 |
| AU2008226051A1 (en) | 2008-09-18 |
| JP5081931B2 (ja) | 2012-11-28 |
| CN101616929A (zh) | 2009-12-30 |
| AR065688A1 (es) | 2009-06-24 |
| KR101182951B1 (ko) | 2012-09-13 |
| BRPI0808732A2 (pt) | 2014-08-12 |
| EP2118125A1 (en) | 2009-11-18 |
| CA2679647A1 (en) | 2008-09-18 |
| WO2008110332A1 (en) | 2008-09-18 |
| ES2374962T3 (es) | 2012-02-23 |
| CL2008000707A1 (es) | 2008-09-22 |
| TW200902544A (en) | 2009-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |