[go: up one dir, main page]

MX2009008511A - Reduccion de efectos secundarios de tramadol. - Google Patents

Reduccion de efectos secundarios de tramadol.

Info

Publication number
MX2009008511A
MX2009008511A MX2009008511A MX2009008511A MX2009008511A MX 2009008511 A MX2009008511 A MX 2009008511A MX 2009008511 A MX2009008511 A MX 2009008511A MX 2009008511 A MX2009008511 A MX 2009008511A MX 2009008511 A MX2009008511 A MX 2009008511A
Authority
MX
Mexico
Prior art keywords
tramadol
side effects
phosphodiesterase inhibitor
tramadol material
reducing
Prior art date
Application number
MX2009008511A
Other languages
English (en)
Inventor
James V Winkler
Kevin Bilyard
David Bar-Or
Original Assignee
Dmi Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dmi Biosciences Inc filed Critical Dmi Biosciences Inc
Publication of MX2009008511A publication Critical patent/MX2009008511A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención proporciona métodos para reducir los efectos secundarios de tramadol. Por consiguiente, en una modalidad, la presente invención proporciona un método para reducir la incidencia de los efectos secundarios recientemente descubiertos, relacionados con la función sexual en hombres humanos que toman un material de tramadol. El método comprende administrar un inhibidor de fosfodiesterasa a un hombre que toma el material de tramadol. La presente invención también proporciona composiciones farmacéuticas. En una modalidad, la composición comprende un material de tramadol y un inhibidor de fosfodiesterasa. La presente invención proporciona además equipos. En una modalidad, el equipo comprende un material de tramadol y un inhibidor de fosfodiesterasa.
MX2009008511A 2007-02-12 2008-02-12 Reduccion de efectos secundarios de tramadol. MX2009008511A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88938007P 2007-02-12 2007-02-12
PCT/US2008/053722 WO2008100933A2 (en) 2007-02-12 2008-02-12 Reducing side effects of tramadol

Publications (1)

Publication Number Publication Date
MX2009008511A true MX2009008511A (es) 2010-01-20

Family

ID=39690762

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009008511A MX2009008511A (es) 2007-02-12 2008-02-12 Reduccion de efectos secundarios de tramadol.

Country Status (16)

Country Link
US (3) US20080261991A1 (es)
EP (2) EP2486921A1 (es)
JP (1) JP5550101B2 (es)
KR (2) KR101497509B1 (es)
CN (1) CN101674728A (es)
AU (1) AU2008216363B2 (es)
BR (1) BRPI0807281A2 (es)
CA (1) CA2677691C (es)
DK (1) DK2114147T3 (es)
ES (1) ES2384127T3 (es)
MX (1) MX2009008511A (es)
NZ (1) NZ579170A (es)
PL (1) PL2114147T3 (es)
SG (1) SG178775A1 (es)
WO (1) WO2008100933A2 (es)
ZA (1) ZA200906187B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2384481T3 (es) * 2007-02-12 2012-07-05 Dmi Biosciences, Inc. Tratamiento de la eyaculación precoz y la disfunción eréctil co-morbidas
ES2384127T3 (es) * 2007-02-12 2012-06-29 Dmi Biosciences, Inc. Reducción de los efectos secundarios del tramadol
US8202525B2 (en) 2009-12-22 2012-06-19 Pondera Biotechnologies, LLC Methods and compositions for treating distress dysfunction and enhancing safety and efficacy of specific medications
WO2012142273A1 (en) 2011-04-12 2012-10-18 Revogenex Inc. Intravenous administration of tramadol
WO2015134695A1 (en) * 2014-03-07 2015-09-11 Vyrix Pharmaceuticals, Inc. Method of mitigating the side effects of a phosphodiesterase type v inhibitor in a subject
US20160228485A1 (en) * 2015-02-11 2016-08-11 Latasha M. Watts Skin medicating system
US9693949B1 (en) 2015-12-22 2017-07-04 Revogenex Ireland Ltd Intravenous administration of tramadol
US9980900B2 (en) 2015-12-22 2018-05-29 Revogenex Ireland Ltd Intravenous administration of tramadol
US10022321B2 (en) 2016-06-30 2018-07-17 Revogenex Ireland Ltd. Intravenous administration of tramadol
WO2020006606A1 (en) * 2018-07-05 2020-01-09 Helium 3 Resources Pty Ltd A pharmaceutical composition and method of use of same
CA3187455A1 (en) * 2020-07-29 2022-02-03 Stephen Kwaku DORDUNOO Pharmaceutical formulations comprising tadalafil
US11504332B2 (en) * 2021-03-23 2022-11-22 Vk Research Associates Inc. Phosphodiesterase-4 inhibitor combinations, methods of making, and methods of use thereof
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3830934A (en) * 1967-07-27 1974-08-20 Gruenenthal Chemie Analgesic and antitussive compositions and methods
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
US4127118B1 (en) 1977-03-16 1995-12-19 Alvaro Latorre Method of effecting and enhancing an erection
ES2124225T3 (es) 1990-04-25 1999-02-01 Vivus Inc Tratamiento de la disfuncion erectil.
US5250534A (en) 1990-06-20 1993-10-05 Pfizer Inc. Pyrazolopyrimidinone antianginal agents
US5151448A (en) * 1991-07-12 1992-09-29 Crenshaw Roger T Method for treating premature ejaculation
DK0566709T5 (da) * 1991-09-06 2009-05-18 Ortho Mcneil Janssen Pharm Præparat indeholdende et tramadolmateriale og acetaminophen og anvendelse deraf
US5223541A (en) 1991-09-13 1993-06-29 Mcneilab, Inc. Tramadol n-oxide material, enantiomers and compositions thereof, and their use
US5512578A (en) * 1992-09-21 1996-04-30 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opiod agonists
US5580876A (en) * 1992-09-21 1996-12-03 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
US20010006967A1 (en) 1992-09-21 2001-07-05 Stanley M. Crain Method of simultaneously enhancing analgesic potency and attenuating adverse side effects caused by tramadol and other bimodally-acting opioid agonists
USRE36547E (en) * 1992-09-21 2000-02-01 Albert Einstein College Of Medicine Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists
US6096756A (en) * 1992-09-21 2000-08-01 Albert Einstein College Of Medicine Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
US5472943A (en) * 1992-09-21 1995-12-05 Albert Einstein College Of Medicine Of Yeshiva University, Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other opioid agonists
IL119660A (en) 1993-05-10 2002-09-12 Euro Celtique Sa Controlled release formulation comprising tramadol
GB9311920D0 (en) 1993-06-09 1993-07-28 Pfizer Ltd Therapeutic agents
DE4329794C2 (de) 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung
GB9401090D0 (en) 1994-01-21 1994-03-16 Glaxo Lab Sa Chemical compounds
US5861431A (en) 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
GB9514464D0 (en) 1995-07-14 1995-09-13 Glaxo Lab Sa Medicaments
US6017963A (en) 1995-11-14 2000-01-25 Euro-Celtique, S.A. Formulation for intranasal administration
DE19601745C1 (de) * 1996-01-19 1997-10-09 Gruenenthal Gmbh Verfahren zur Racematspaltung von Tramadol
DE19601744C2 (de) * 1996-01-19 1998-04-16 Gruenenthal Gmbh Verfahren zur Herstellung der Enantiomeren von O-Demethyltramadol
IL119121A (en) 1996-08-22 2000-11-21 Chemagis Ltd Process for the purification of (RR-SS)-2-dimethylaminomethyl-1-(3-methoxyphenyl)cyclohexanol hydrochloride
US6331543B1 (en) * 1996-11-01 2001-12-18 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
CN1251987A (zh) * 1997-03-11 2000-05-03 达尔文发现有限公司 含有r－和s－对映体分离部分的剂型
AU6747698A (en) * 1997-04-11 1998-11-11 Nippon Shinyaku Co. Ltd. Remedies for frequent urination and urinary incontinence
US6403597B1 (en) * 1997-10-28 2002-06-11 Vivus, Inc. Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
US6037360A (en) * 1997-10-28 2000-03-14 Vivus, Incorporated Administration of 5-HT3 receptor antagonists to treat premature ejaculation
CA2309332C (en) 1997-11-12 2002-12-03 Bayer Aktiengesellschaft 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
CA2314893C (en) * 1997-12-22 2005-09-13 Euro-Celtique, S.A. Opioid agonist/antagonist combinations
UA53774C2 (uk) * 1997-12-22 2003-02-17 Еро-Селтік, С.А. Спосіб запобігання зловживанню лікарськими формами, що містять опіоїди
US6375957B1 (en) * 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
US6339826B2 (en) * 1998-05-05 2002-01-15 International Business Machines Corp. Client-server system for maintaining a user desktop consistent with server application user access permissions
GT199900061A (es) * 1998-05-15 2000-10-14 Pfizer Formulaciones farmaceuticas.
US6156342A (en) * 1998-05-26 2000-12-05 Andex Pharmaceuticals, Inc. Controlled release oral dosage form
US6403605B1 (en) * 1998-05-29 2002-06-11 Queen's University At Kingston Methods for the normalization of sexual response and amelioration of long term genital tissue degradation
US6339106B1 (en) * 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
US6331571B1 (en) * 1998-08-24 2001-12-18 Sepracor, Inc. Methods of treating and preventing attention deficit disorders
US6476078B2 (en) * 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
KR20010080364A (ko) 1998-12-02 2001-08-22 마르크 젠너 치료제 및 그 용도
US6087362A (en) * 1999-03-16 2000-07-11 Pentech Pharmaceuticals, Inc. Apomorphine and sildenafil composition
US6943166B1 (en) 1999-04-30 2005-09-13 Lilly Icos Llc. Compositions comprising phosphodiesterase inhabitors for the treatment of sexual disfunction
US6765010B2 (en) 1999-05-06 2004-07-20 Pain Therapeutics, Inc. Compositions and methods for enhancing analgesic potency of tramadol and attenuating its adverse side effects
US20030055070A1 (en) * 1999-07-01 2003-03-20 Wilma Harrison Phosphodiesterase type 5 (PDE5) inhibitors for the treatment of selective serotonin reuptake inhibitor (SSR) induced sexual dysfunction
US6821975B1 (en) 1999-08-03 2004-11-23 Lilly Icos Llc Beta-carboline drug products
US6451806B2 (en) * 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
US6297286B1 (en) 1999-11-09 2001-10-02 Darwin Discovery, Ltd. Therapeutic use and formulation
US6716449B2 (en) * 2000-02-08 2004-04-06 Euro-Celtique S.A. Controlled-release compositions containing opioid agonist and antagonist
US20020091129A1 (en) * 2000-11-20 2002-07-11 Mitradev Boolell Treatment of premature ejaculation
NZ528935A (en) * 2001-03-16 2004-10-29 Dmi Biosciences Inc Method of delaying ejaculation
EP1389092B1 (en) * 2001-05-11 2006-11-15 Endo Pharmaceuticals Inc. Abuse-resistant opioid dosage form
RU2004106619A (ru) * 2001-08-06 2005-07-10 Эро-Селтик С.А. (Lu) Композиции опиоидного агониста, содержащие высвобождаемый и изолированный антагонист
US7019010B2 (en) * 2001-09-27 2006-03-28 Novertis Ag Combinations
US6943171B2 (en) 2001-11-09 2005-09-13 Schering Corporation Polycyclic guanine derivative phosphodiesterase V inhibitors
AU2003217669A1 (en) * 2002-02-25 2003-09-09 Smithkline Beecham Corporation A method of recuding anti-neoplastic agent induced side effects
US20040202717A1 (en) * 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
US20050054688A1 (en) * 2003-08-08 2005-03-10 Pfizer Inc Selective serotonin reuptake inhibitors in the treatment of disease
US20060149480A1 (en) * 2004-02-26 2006-07-06 Lundeen James E Method of making combination medicament and medicament made thereby
JP4475098B2 (ja) * 2004-11-02 2010-06-09 ソニー株式会社 記憶素子及びその駆動方法
CA2599662A1 (en) * 2005-03-01 2006-09-08 Pfizer Limited Use of pde7 inhibitors for the treatment of neuropathic pain
US8604082B2 (en) * 2005-12-13 2013-12-10 Trinity Laboratories, Inc. Method to treat premature ejaculation in humans
US20070185145A1 (en) * 2006-02-03 2007-08-09 Royds Robert B Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same
ES2384127T3 (es) * 2007-02-12 2012-06-29 Dmi Biosciences, Inc. Reducción de los efectos secundarios del tramadol
ES2384481T3 (es) * 2007-02-12 2012-07-05 Dmi Biosciences, Inc. Tratamiento de la eyaculación precoz y la disfunción eréctil co-morbidas
WO2008131256A1 (en) * 2007-04-19 2008-10-30 Trinity Laboratories Inc. Improved treatments for premature ejaculation in humans

Also Published As

Publication number Publication date
EP2486921A1 (en) 2012-08-15
CA2677691C (en) 2012-07-31
CN101674728A (zh) 2010-03-17
WO2008100933A2 (en) 2008-08-21
US20120018333A1 (en) 2012-01-26
SG178775A1 (en) 2012-03-29
EP2114147B9 (en) 2013-04-10
AU2008216363B2 (en) 2014-05-08
BRPI0807281A2 (pt) 2014-04-29
ZA200906187B (en) 2013-02-27
US20080261991A1 (en) 2008-10-23
EP2114147A4 (en) 2010-04-07
PL2114147T3 (pl) 2012-10-31
AU2008216363A1 (en) 2008-08-21
HK1131730A1 (en) 2010-02-05
JP2010518168A (ja) 2010-05-27
EP2114147A2 (en) 2009-11-11
ES2384127T3 (es) 2012-06-29
WO2008100933A3 (en) 2008-10-16
DK2114147T3 (da) 2012-06-25
EP2114147B1 (en) 2012-05-16
JP5550101B2 (ja) 2014-07-16
CA2677691A1 (en) 2008-08-21
US20130338166A1 (en) 2013-12-19
KR101497509B1 (ko) 2015-03-03
KR20130122023A (ko) 2013-11-06
NZ579170A (en) 2012-05-25
KR20090127277A (ko) 2009-12-10

Similar Documents

Publication Publication Date Title
MX2009008511A (es) Reduccion de efectos secundarios de tramadol.
PH12014500053A1 (en) Proteasome inhibitors
TW200738263A (en) ANG2 and VEGF inhibitor combinations
MY160041A (en) Compositions and methods for treating parasitic infections
MX2009007254A (es) Composiciones de tableta en tableta.
SG164368A1 (en) Treatment of cancer
TW200740803A (en) Heterocyclic derivatives as modulators of ion channels
PH12015501193A1 (en) Boronate ester compounds and pharmaceutical compositions thereof
NO20092637L (no) Fremgangsmater for behandling
TW200618817A (en) Diffractive colorants for cosmetics
MY166653A (en) Derivatives of 1-amino-2-cyclobutylethylboronic acid
MX2010006154A (es) Tratamiento del cancer con combinaciones de inhibidores de la topoisomerasa e inhibidores de la poli-adp-ribosa-polimerasa.
IL187382A0 (en) Bicyclic derivatives as modulators of ion channels
MX2012000396A (es) Metodos y composiciones para uso en tartamientos celulares.
DE602005018043D1 (de) Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung
TW200719913A (en) Anti-madcam antibody compositions
WO2008030883A3 (en) Treatment of cancer
TW200728285A (en) Diacylindazole derivatives as inhibitors of lipases and phospholipases
MX2010000266A (es) Un método para disminuir los síntomas del consumo de alcohol.
NO20092146L (no) Anvendelse av 3-ALFA-Androstandiol, valgfritt i kombinasjon med en 5-HT1A-agonist, i behandlingen av seksuell dysfunksjon
ZA200702375B (en) Quinazolines useful as modulators of ion channels
AU2008321142A8 (en) Heterocyclic derivatives as modulators of ion channels
BRPI0617294B8 (pt) composição farmacêutica em gel hidroalcóolico e uso de testosterona
WO2007062413A3 (en) Use of parp-1 inhibitors
TW200730513A (en) Carbamoylbenzotriazole derivatives as inhibitors of lipases and phospholipases

Legal Events

Date Code Title Description
FG Grant or registration
GB Transfer or rights