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MX2009006699A - Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos. - Google Patents

Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos.

Info

Publication number
MX2009006699A
MX2009006699A MX2009006699A MX2009006699A MX2009006699A MX 2009006699 A MX2009006699 A MX 2009006699A MX 2009006699 A MX2009006699 A MX 2009006699A MX 2009006699 A MX2009006699 A MX 2009006699A MX 2009006699 A MX2009006699 A MX 2009006699A
Authority
MX
Mexico
Prior art keywords
orally disintegrating
disintegrating tablets
composition
api
active ingredients
Prior art date
Application number
MX2009006699A
Other languages
English (en)
Inventor
Stephen H Wu
Jae Han Park
Kevin M Holman
Glen A Bish
Donald G Krieger
Daniel S Ramlose
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of MX2009006699A publication Critical patent/MX2009006699A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a composiciones y a métodos mejorados para preparar tabletas oralmente disgretantes (COD). En un aspecto de la presente invención, la COD contiene además al menos un ingrediente activo farmacéutico (API). En otro aspecto de la presente invención, la COD contiene una concentración elevada de al menos un API. Específicamente, las COD descritas en esta invención que contienen una concentración elevada de API pueden contener hasta aproximadamente el 70% p/p de ingrediente activo farmacéutico en una dosis unitaria, mientras que al mismo tiempo exhiben los convenientes atributos de tiempo de disgregación rápido, dureza y friabilidad aceptables para atravesar envases tipo blíster o para ser embotellados y una sensación bucal aceptable.
MX2009006699A 2006-12-21 2007-12-20 Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos. MX2009006699A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87638306P 2006-12-21 2006-12-21
US94820807P 2007-07-06 2007-07-06
US95263807P 2007-07-30 2007-07-30
PCT/US2007/026185 WO2008079343A2 (en) 2006-12-21 2007-12-20 Composition of and method for preparing orally disintegrating tablets containing a high dose of pharmaceutically active ingredients

Publications (1)

Publication Number Publication Date
MX2009006699A true MX2009006699A (es) 2009-06-30

Family

ID=39345530

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006699A MX2009006699A (es) 2006-12-21 2007-12-20 Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos.

Country Status (6)

Country Link
US (1) US20100055179A1 (es)
EP (1) EP2101739A2 (es)
AU (1) AU2007338751A1 (es)
CA (1) CA2673458A1 (es)
MX (1) MX2009006699A (es)
WO (1) WO2008079343A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
NZ572106A (en) 2006-03-31 2010-12-24 Rubicon Res Private Ltd Directly compressible composite for orally disintegrating tablets
WO2010126828A1 (en) * 2009-04-28 2010-11-04 Isp Investments Inc. Co-processed excipient compositions
CA2765033C (en) 2009-06-12 2020-07-14 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
WO2018142296A2 (en) * 2017-02-01 2018-08-09 Zion Azar Systems methods devices apparatuses circuits and computer executable code for production and topical application of a therapeutic substance
JP2021512051A (ja) * 2018-01-23 2021-05-13 ギラ セラピューティクス インコーポレイテッドＧｉｌａ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． ペプチドｙｙ薬学的調剤物、組成物、および方法
WO2024200015A1 (en) * 2023-03-28 2024-10-03 Evonik Operations Gmbh Process for the production of a granulate and a granulate, in particular a granulate compound of excipients

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CH658188A5 (de) * 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.
DE69727922T2 (de) * 1996-04-16 2005-01-20 Novartis Consumer Health S.A. Schnell zerfallende orale dosierungsform
JP2002505269A (ja) * 1998-03-06 2002-02-19 エウランド インターナショナル ソシエタ ペル アチオニ 急速崩壊錠剤
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
AU765526B2 (en) * 1999-08-17 2003-09-18 Novartis Consumer Health S.A. Rapidly dissolving dosage form and process for making same
EP1244428A1 (en) * 1999-12-06 2002-10-02 Edward Mendell Co., Inc. Pharmaceutical superdisintegrant
US20030185886A1 (en) * 2000-05-26 2003-10-02 Hanmi Pharm. Co., Ltd. Process for the preparation of rapidly disintegrating tablet
EP1366760B1 (en) * 2001-02-15 2010-06-30 Mitsubishi Tanabe Pharma Corporation Tablets quickly disintegrated in oral cavity
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US7037524B2 (en) * 2001-10-03 2006-05-02 Herbalscience, Llc Oral delivery of a botanical
CA2465159A1 (en) * 2001-11-02 2003-05-15 Sandoz Inc. Process for preparing quick dissolving, high loading ribavirin compositions
SE0200154D0 (sv) * 2002-01-21 2002-01-21 Galenica Ab New process
US20030161875A1 (en) * 2002-02-27 2003-08-28 Deepak Murpani Fast dissolving tablets of cyclooxygenase-2 enzyme inhibitors
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CA2554012A1 (en) * 2003-01-21 2004-08-05 Smartrix Technologies Inc. Oral dosage formulation
JP3841804B2 (ja) * 2003-10-15 2006-11-08 富士化学工業株式会社 口腔内速崩壊性錠剤用の組成物
US8545881B2 (en) * 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US20050244347A1 (en) * 2004-04-30 2005-11-03 Mehra Dev K Oral care products comprising calcium phosphates
JP4277904B2 (ja) * 2004-04-30 2009-06-10 アステラス製薬株式会社 経口投与用時限放出型粒子状医薬組成物及び該組成物を含有する口腔内速崩壊錠
US9884014B2 (en) * 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
CN101277720A (zh) * 2005-09-01 2008-10-01 卫材R&D管理有限公司 崩解性被改善的药物组合物的制备方法
WO2007028247A1 (en) * 2005-09-09 2007-03-15 University Of Manitoba Fast-disintegrating epinephrine tablets for buccal or sublingual administration
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Also Published As

Publication number Publication date
AU2007338751A1 (en) 2008-07-03
WO2008079343A3 (en) 2008-08-14
CA2673458A1 (en) 2008-07-03
WO2008079343A2 (en) 2008-07-03
US20100055179A1 (en) 2010-03-04
EP2101739A2 (en) 2009-09-23

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Legal Events

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