MX2009003735A - Composicion en deposito inyectable y su procedimiento de preparacion. - Google Patents
Composicion en deposito inyectable y su procedimiento de preparacion.Info
- Publication number
- MX2009003735A MX2009003735A MX2009003735A MX2009003735A MX2009003735A MX 2009003735 A MX2009003735 A MX 2009003735A MX 2009003735 A MX2009003735 A MX 2009003735A MX 2009003735 A MX2009003735 A MX 2009003735A MX 2009003735 A MX2009003735 A MX 2009003735A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- preparation
- novel
- letrozole
- administration
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 239000007972 injectable composition Substances 0.000 abstract 2
- HPJKCIUCZWXJDR-UHFFFAOYSA-N letrozole Chemical compound C1=CC(C#N)=CC=C1C(N1N=CN=C1)C1=CC=C(C#N)C=C1 HPJKCIUCZWXJDR-UHFFFAOYSA-N 0.000 abstract 2
- 229960003881 letrozole Drugs 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- DRHKJLXJIQTDTD-OAHLLOKOSA-N Tamsulosine Chemical compound CCOC1=CC=CC=C1OCCN[C@H](C)CC1=CC=C(OC)C(S(N)(=O)=O)=C1 DRHKJLXJIQTDTD-OAHLLOKOSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 229960002613 tamsulosin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se proveen composiciones inyectables novedosas que comprenden un agente activo el cual es tamsulosina o letrozol o sus sales farmacéuticamente aceptables, derivados, isómeros, polimorfos, solvatos, hidratos, análogos, enantiómeros, formas tautoméricas o mezclas de los mismos y uno o más excipientes farmacéuticamente aceptables en donde las composiciones preferiblemente se formulan como micropartículas o nanopartículas biodegradables las cuales se pueden reconstituir opcionalmente con un vehículo acuoso, hidro-alcohólico o liquido oleoso antes de la administración; las composiciones inyectables novedosas de la presente invención preferiblemente forman un deposito después de la administración in vivo y están en la forma de una composición gelificante in situ o una composición en implante la cual provee una liberación prolongada de tamsulosina o letrozol por periodos extendidos de tiempo; también se describen procedimientos para la preparación de dichas composiciones novedosas y métodos de uso de los mismos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2195DE2006 | 2006-10-05 | ||
| PCT/IN2007/000473 WO2008041246A2 (en) | 2006-10-05 | 2007-10-03 | Injectable depot composition and its' process of preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009003735A true MX2009003735A (es) | 2009-04-22 |
Family
ID=39268891
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009003735A MX2009003735A (es) | 2006-10-05 | 2007-10-03 | Composicion en deposito inyectable y su procedimiento de preparacion. |
| MX2009003737A MX2009003737A (es) | 2006-10-05 | 2007-10-03 | Composicion inyectable en deposito y su procedimiento de preparacion. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009003737A MX2009003737A (es) | 2006-10-05 | 2007-10-03 | Composicion inyectable en deposito y su procedimiento de preparacion. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20100015195A1 (es) |
| EP (2) | EP2086505A2 (es) |
| JP (2) | JP2010505821A (es) |
| KR (2) | KR20090094811A (es) |
| CN (2) | CN101541313A (es) |
| AR (1) | AR063120A1 (es) |
| AU (2) | AU2007303793A1 (es) |
| BR (2) | BRPI0718288A2 (es) |
| CA (2) | CA2665101A1 (es) |
| CL (1) | CL2007002851A1 (es) |
| EA (1) | EA200970348A1 (es) |
| IL (2) | IL197946A0 (es) |
| MA (2) | MA30814B1 (es) |
| MX (2) | MX2009003735A (es) |
| RU (1) | RU2009116933A (es) |
| TN (2) | TN2009000124A1 (es) |
| WO (2) | WO2008041246A2 (es) |
Families Citing this family (109)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
| US8110209B2 (en) * | 2002-12-20 | 2012-02-07 | Xeris Pharmaceuticals Inc. | Intracutaneous injection |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| US9205046B2 (en) * | 2005-04-25 | 2015-12-08 | The Governing Council Of The University Of Toronto | Enhanced stability of inverse thermal gelling composite hydrogels |
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| NZ593017A (en) | 2006-08-09 | 2011-08-26 | Intarcia Therapeutics Inc | Piston assembly for positioning lumen in an osmotic delivery system having groove to retain elastomeric O-ring |
| RU2440097C2 (ru) | 2007-04-23 | 2012-01-20 | Интарсия Терапьютикс, Инк. | Способ лечения диабета ii типа и ожирения, осмотическое устройство для доставки и способ его изготовления |
| WO2008153611A2 (en) | 2007-05-25 | 2008-12-18 | Qlt Usa, Inc. | Sustained delivery formulations of risperidone compounds |
| MX2009013663A (es) * | 2007-06-22 | 2010-01-27 | Scidose Llc | Formulacion solubilizada de docetaxel sin tween 80. |
| ES2529746T3 (es) * | 2007-06-25 | 2015-02-25 | Otsuka Pharmaceutical Co., Ltd. | Microesferas con una estructura de núcleo/cáscara |
| AR070033A1 (es) * | 2007-11-06 | 2010-03-10 | Panacea Biotec Ltd | Composiciones inyectables, sus procesos y usos |
| WO2009102467A2 (en) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| CA2716576A1 (en) * | 2008-03-07 | 2009-09-11 | Nageswara R. Palepu | Fulvestrant formulations |
| US8524267B2 (en) * | 2008-04-18 | 2013-09-03 | Warsaw Orthopedic, Inc. | Dexamethasone formulations in a biodegradable material |
| CN101569622B (zh) * | 2008-04-30 | 2012-11-21 | 天津药物研究院 | 一种用于注射给药的药物制剂及其制备方法 |
| EA014044B1 (ru) * | 2008-07-09 | 2010-08-30 | Общество С Ограниченной Ответственностью "Аква-Альянс" | Наносомальная лекарственная форма препарата пролонгированного действия для лечения гепатита с (варианты) |
| PL2341905T5 (pl) | 2008-09-04 | 2024-01-15 | Amylin Pharmaceuticals, Llc | Preparaty o przedłużonym uwalnianiu z wykorzystaniem niewodnych nośników |
| JP2012511519A (ja) * | 2008-12-10 | 2012-05-24 | アンフイ ジョンレン テクノロジー コーポレイション,リミテッド | 制御放出組成物 |
| US9636255B2 (en) | 2009-02-13 | 2017-05-02 | Dose Medical Corporation | Uveoscleral drug delivery implant and methods for implanting the same |
| US8673264B2 (en) | 2009-03-02 | 2014-03-18 | Assistance Publique-Hopitaux De Paris | Injectable biomaterial |
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| AU2010249683B2 (en) | 2009-05-18 | 2015-06-25 | Glaukos Corporation | Drug eluting ocular implant |
| SMT201700583T1 (it) | 2009-09-28 | 2018-01-11 | Intarcia Therapeutics Inc | Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario |
| CN101669942A (zh) * | 2009-09-29 | 2010-03-17 | 北京华禧联合科技发展有限公司 | 难溶性药物组合物 |
| US8912228B2 (en) | 2009-10-19 | 2014-12-16 | Scidose Llc | Docetaxel formulations with lipoic acid |
| US8476310B2 (en) | 2009-10-19 | 2013-07-02 | Scidose Llc | Docetaxel formulations with lipoic acid |
| US20110092579A1 (en) * | 2009-10-19 | 2011-04-21 | Scidose Llc | Solubilized formulation of docetaxel |
| US7772274B1 (en) | 2009-10-19 | 2010-08-10 | Scidose, Llc | Docetaxel formulations with lipoic acid |
| US8541465B2 (en) * | 2009-10-19 | 2013-09-24 | Scidose, Llc | Docetaxel formulations with lipoic acid and/or dihydrolipoic acid |
| US9504698B2 (en) * | 2009-10-29 | 2016-11-29 | Warsaw Orthopedic, Inc. | Flowable composition that sets to a substantially non-flowable state |
| RU2548753C2 (ru) | 2009-11-16 | 2015-04-20 | Ипсен Фарма С.А.С. | Фармацевтические композиции лигандов рецепторов меланокортинов |
| KR101589191B1 (ko) * | 2010-03-15 | 2016-01-27 | 입센 파마 에스.에이.에스. | 성장 호르몬의 분비를 촉진시키는 수용체 리간드의 약학 조성물 |
| EP2552416B1 (en) * | 2010-03-29 | 2017-10-25 | Evonik Corporation | Compositions and methods for improved retention of a pharmaceutical composition at a local administration site |
| US10285936B2 (en) * | 2010-05-31 | 2019-05-14 | Laboratorios Farmacéuticos Rovi, S.A. | Injectable composition with aromatase inhibitor |
| US10335366B2 (en) | 2010-05-31 | 2019-07-02 | Laboratorios Farmacéuticos Rovi, S.A. | Risperidone or paliperidone implant formulation |
| US10350159B2 (en) * | 2010-05-31 | 2019-07-16 | Laboratories Farmacéuticos Rovi, S.A. | Paliperidone implant formulation |
| ES2390439B1 (es) | 2012-08-03 | 2013-09-27 | Laboratorios Farmacéuticos Rovi, S.A. | Composición inyectable |
| US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
| GB2481017B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
| DE102010023949A1 (de) * | 2010-06-16 | 2011-12-22 | F. Holzer Gmbh | In-situ Lecithin-Mikroemulsionsgel-Formulierung |
| US20120046225A1 (en) | 2010-07-19 | 2012-02-23 | The Regents Of The University Of Colorado, A Body Corporate | Stable glucagon formulations for the treatment of hypoglycemia |
| PH12012502076A1 (en) * | 2010-08-24 | 2013-02-04 | Otsuka Pharma Co Ltd | Suspension and cake composition containing carbostyryl derivative and silicone oil and/or silicone oil derivative |
| WO2012058091A2 (en) * | 2010-10-28 | 2012-05-03 | Alpha To Omega Pharmaceutical Consultants, Inc. | Aripiprazole compositions and methods for its transdermal delivery |
| US9757374B2 (en) | 2010-10-28 | 2017-09-12 | Aequus Pharmaceuticals Inc. | Aripiprazole compositions and methods for its transdermal delivery |
| US9668915B2 (en) | 2010-11-24 | 2017-06-06 | Dose Medical Corporation | Drug eluting ocular implant |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| MX342675B (es) | 2011-03-10 | 2016-10-07 | Xeris Pharmaceuticals Inc | Formulaciones estables para inyeccion parenteral de farmacos de peptido. |
| EP3156056B1 (en) * | 2011-03-18 | 2023-12-06 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising sorbitan esters |
| US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
| WO2013067022A1 (en) | 2011-10-31 | 2013-05-10 | Xeris Pharmaceuticals, Inc. | Formulations for the treatment of diabetes |
| US11179468B2 (en) | 2012-04-09 | 2021-11-23 | Eagle Pharmaceuticals, Inc. | Fulvestrant formulations |
| JOP20200109A1 (ar) * | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
| EP2705835A1 (en) * | 2012-06-08 | 2014-03-12 | Ipsen Pharma S.A.S. | Aqueous gelling compositions of soluble active pharmaceutical peptides providing modified release |
| CN103483353B (zh) * | 2012-06-13 | 2016-02-24 | 上海现代药物制剂工程研究中心有限公司 | 二硫杂环戊烯并吡咯酮化合物的纳米粒及制备方法 |
| US9125805B2 (en) | 2012-06-27 | 2015-09-08 | Xeris Pharmaceuticals, Inc. | Stable formulations for parenteral injection of small molecule drugs |
| US9018162B2 (en) | 2013-02-06 | 2015-04-28 | Xeris Pharmaceuticals, Inc. | Methods for rapidly treating severe hypoglycemia |
| US10517759B2 (en) | 2013-03-15 | 2019-12-31 | Glaukos Corporation | Glaucoma stent and methods thereof for glaucoma treatment |
| KR101811797B1 (ko) * | 2013-04-03 | 2017-12-22 | 동국제약 주식회사 | 도네페질을 포함하는 비경구투여용 약제학적 조성물 |
| WO2014179615A2 (en) * | 2013-05-01 | 2014-11-06 | Dae Won Park | Biodegradable copolymers, systems including the copolymers, and methods of forming and using same |
| US20160200891A1 (en) * | 2013-08-22 | 2016-07-14 | Polyvalor Limited Partnership | Porous gels and methods for their preparation |
| JP2015093854A (ja) * | 2013-11-12 | 2015-05-18 | 株式会社クレハ | 水性組成物および加水分解抑制方法 |
| CH708890B1 (de) * | 2013-11-22 | 2018-03-15 | Sandel Thomas | Ball, vorzugsweise Golfball, sowie ein mit dem Ball kommunizierbares elektronisches Gerät. |
| US20150174254A1 (en) | 2013-12-23 | 2015-06-25 | Mcneil-Ppc, Inc. | Topical gel compositions including polycaprolactone polymer and methods for enhancing the topical application of a benefit agent |
| GB201404139D0 (en) | 2014-03-10 | 2014-04-23 | Rb Pharmaceuticals Ltd | Sustained release buprenorphine solution formulations |
| WO2015184173A1 (en) | 2014-05-29 | 2015-12-03 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| CA2957399C (en) | 2014-08-06 | 2023-09-26 | Xeris Pharmaceuticals, Inc. | Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| CR20170191A (es) * | 2014-11-10 | 2017-09-29 | Glaxosmithkline Intellectual Property (No 2) Ltd | Composiciones farmacéuticas de acción prolongada para la hepatitis c |
| EP3028721A1 (en) * | 2014-12-05 | 2016-06-08 | Exchange Imaging Technologies GmbH | Nanoparticle formulation having reverse-thermal gelation properties for injection |
| KR101692314B1 (ko) * | 2015-03-27 | 2017-01-03 | 주식회사 주빅 | 지용성 약물의 생분해성 고분자 내 용해 시스템: 스마트 폴리머 시스템 |
| US9844558B1 (en) | 2015-04-30 | 2017-12-19 | Amag Pharmaceuticals, Inc. | Methods of reducing risk of preterm birth |
| JP6993235B2 (ja) | 2015-06-03 | 2022-01-13 | インターシア セラピューティクス,インコーポレイティド | インプラントの設置及び撤去システム |
| US9649364B2 (en) | 2015-09-25 | 2017-05-16 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic formulations in aprotic polar solvents |
| US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
| WO2017053885A1 (en) | 2015-09-25 | 2017-03-30 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
| US11590205B2 (en) | 2015-09-25 | 2023-02-28 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents |
| US20170128424A1 (en) * | 2015-11-11 | 2017-05-11 | Qrono, Inc. | Sustained release pharmaceutical compositions and methods of use |
| WO2017105512A1 (en) * | 2015-12-18 | 2017-06-22 | Proinvet Innovations S.A. | Formulations and methods for controlling the reproductive cycle and ovulation |
| US11318043B2 (en) | 2016-04-20 | 2022-05-03 | Dose Medical Corporation | Bioresorbable ocular drug delivery device |
| US20190282588A1 (en) * | 2016-05-16 | 2019-09-19 | Amag Pharmaceuticals, Inc. | Polymeric extended release compositions of hydroxyprogesterone caproate and methods of using same |
| EP3733694A1 (en) | 2016-05-16 | 2020-11-04 | Intarcia Therapeutics, Inc | Glucagon-receptor selective polypeptides and methods of use thereof |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| WO2018015915A1 (en) * | 2016-07-22 | 2018-01-25 | Cadila Healthcare Limited | A parenteral controlled release composition of an atypical antipsychotic agent |
| JP7286542B2 (ja) | 2017-01-03 | 2023-06-05 | インターシア セラピューティクス,インコーポレイティド | Glp-1受容体アゴニストの持続的投与及び薬物の同時投与を含む方法 |
| KR20190101408A (ko) * | 2017-01-23 | 2019-08-30 | 세이비어 라이프텍 코퍼레이션 | 활성 성분의 미립자 제조 |
| CN116270486A (zh) * | 2017-01-24 | 2023-06-23 | 广州帝奇医药技术有限公司 | 水难溶或微溶性药物缓释组合物及其制备方法 |
| CN106822043A (zh) * | 2017-01-24 | 2017-06-13 | 广州帝奇医药技术有限公司 | 利培酮缓释组合物及其制备方法 |
| CN106822042A (zh) * | 2017-01-24 | 2017-06-13 | 广州帝奇医药技术有限公司 | 一种利培酮缓释组合物及其制备方法 |
| CN106727422B (zh) * | 2017-03-09 | 2018-10-02 | 王秋玉 | 一种聚对二氧环己酮为核的核-壳双层微球及其制备方法和应用 |
| EP4378463A3 (en) | 2017-06-02 | 2024-10-23 | Xeris Pharmaceuticals, Inc. | Precipitation resistant small molecule drug formulations |
| KR20240155974A (ko) | 2017-09-11 | 2024-10-29 | 아토사 테라퓨틱스, 인크. | 엔독시펜을 제조 및 사용하는 방법 |
| WO2019053465A1 (en) | 2017-09-15 | 2019-03-21 | Oxular Limited | OPHTHALMIC DELIVERY DEVICE |
| UA128502C2 (uk) * | 2018-03-23 | 2024-07-31 | Лаборатуар Мажор | Застосування композиції у негормональному способі контрацепції для суб’єкта чоловічої статі |
| PE20210047A1 (es) | 2018-06-12 | 2021-01-08 | Farm Rovi Lab Sa | Composicion inyectable |
| EP3833318A4 (en) * | 2018-08-10 | 2022-05-11 | Ephemeral Solutions, Inc. | PARTICLES CONTAINING COLORING AGENTS AND METHODS FOR USING THEM |
| WO2020256340A2 (ko) | 2019-06-21 | 2020-12-24 | 고려대학교산학협력단 | 체내 부피 유지 제제, 이를 포함하는 주사제 및 이의 제조방법 |
| AU2020300624A1 (en) | 2019-07-03 | 2022-02-03 | Atossa Therapeutics, Inc. | Sustained release compositions of endoxifen |
| CN111388744B (zh) * | 2020-01-15 | 2021-05-18 | 华中科技大学 | 一种凝胶贮库及其制法与制备术后止血制剂的应用 |
| US20220047566A1 (en) * | 2020-08-17 | 2022-02-17 | Humanwell Pharmaceutical US | Long acting in-situ forming/gelling compositions |
| CN111956599B (zh) * | 2020-09-29 | 2023-02-17 | 江苏集萃新型药物制剂技术研究所有限公司 | 皮下植入药剂及其组合物和制备方法 |
| KR102266384B1 (ko) * | 2021-01-25 | 2021-06-21 | 주식회사 울트라브이 | 필러용 생분해성 고분자 미세입자, 이를 포함한 필러용 동결건조체, 그 제조방법 및 상기 동결건조체를 포함하는 필러용 주사제 |
| US12318387B2 (en) | 2021-07-16 | 2025-06-03 | Laboratorios Farmaceuticos Rovi, S.A. | Method of treating acute exacerbation of schizophrenia with long-acting injectable depot composition |
| KR102652905B1 (ko) * | 2021-08-09 | 2024-04-01 | 주식회사 메디폴리머 | 주사용 사전-제형 및 이를 이용한 도네페질 초기방출 억제형 키트 |
| TW202313047A (zh) | 2021-09-21 | 2023-04-01 | 西班牙商禾霏藥品實驗室有限公司 | 抗精神病可注射儲積型組合物 |
| AU2023281232A1 (en) | 2022-05-18 | 2024-10-24 | Laboratorios Farmacéuticos Rovi, S.A. | Prolonged-release injectable compositions for use in treatment with risperidone together with cyp2d6 enzyme inhibitors |
| WO2024151625A1 (en) * | 2023-01-10 | 2024-07-18 | Georgetown University | Non-toxic plga compositions and methods of making and using same |
| CN116850146B (zh) * | 2023-05-22 | 2024-05-14 | 济南大学 | 伏硫西汀自由碱或其药用盐长效缓释制剂及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242910A (en) * | 1992-10-13 | 1993-09-07 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
| DE69327542T2 (de) * | 1992-11-17 | 2000-07-06 | Yoshitomi Pharmaceutical Industries, Ltd. | Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung |
| US5650173A (en) * | 1993-11-19 | 1997-07-22 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of biodegradable microparticles containing a biologically active agent |
| GB9718986D0 (en) * | 1997-09-09 | 1997-11-12 | Danbiosyst Uk | Controlled release microsphere delivery system |
| WO2002058672A2 (en) * | 2001-01-26 | 2002-08-01 | Debio Recherche Pharmaceutique S.A. | Microparticles of biodegradable polymer encapsulating a biologically active substance |
| AU2002358831B2 (en) * | 2001-10-10 | 2007-09-06 | Pierre Fabre Medicament | Prolonged release biodegradable microspheres and method for preparing same |
| TW200719903A (en) * | 2005-04-19 | 2007-06-01 | Combinatorx Inc | Compositions for the treatment of neoplasms |
-
2007
- 2007-10-03 KR KR1020097009289A patent/KR20090094811A/ko not_active Abandoned
- 2007-10-03 MX MX2009003735A patent/MX2009003735A/es unknown
- 2007-10-03 EP EP07827598A patent/EP2086505A2/en not_active Withdrawn
- 2007-10-03 AU AU2007303793A patent/AU2007303793A1/en not_active Abandoned
- 2007-10-03 EA EA200970348A patent/EA200970348A1/ru unknown
- 2007-10-03 EP EP07827594A patent/EP2089000A2/en not_active Withdrawn
- 2007-10-03 WO PCT/IN2007/000473 patent/WO2008041246A2/en not_active Ceased
- 2007-10-03 JP JP2009531016A patent/JP2010505821A/ja not_active Withdrawn
- 2007-10-03 CN CNA2007800441089A patent/CN101541313A/zh active Pending
- 2007-10-03 CA CA002665101A patent/CA2665101A1/en not_active Abandoned
- 2007-10-03 US US12/444,197 patent/US20100015195A1/en not_active Abandoned
- 2007-10-03 KR KR1020097009284A patent/KR20090087441A/ko not_active Ceased
- 2007-10-03 AR ARP070104388A patent/AR063120A1/es unknown
- 2007-10-03 RU RU2009116933/15A patent/RU2009116933A/ru not_active Application Discontinuation
- 2007-10-03 WO PCT/IN2007/000454 patent/WO2008041245A2/en not_active Ceased
- 2007-10-03 JP JP2009531014A patent/JP2010505819A/ja not_active Withdrawn
- 2007-10-03 US US12/444,257 patent/US20100098735A1/en not_active Abandoned
- 2007-10-03 CL CL2007002851A patent/CL2007002851A1/es unknown
- 2007-10-03 BR BRPI0718288-0A2A patent/BRPI0718288A2/pt not_active Application Discontinuation
- 2007-10-03 AU AU2007303794A patent/AU2007303794A1/en not_active Abandoned
- 2007-10-03 MX MX2009003737A patent/MX2009003737A/es not_active Application Discontinuation
- 2007-10-03 BR BRPI0720346-2A2A patent/BRPI0720346A2/pt not_active IP Right Cessation
- 2007-10-03 CA CA002665105A patent/CA2665105A1/en not_active Abandoned
- 2007-10-03 CN CNA2007800441356A patent/CN101541316A/zh active Pending
-
2009
- 2009-04-03 TN TNP2009000124A patent/TN2009000124A1/fr unknown
- 2009-04-03 TN TNP2009000125A patent/TN2009000125A1/fr unknown
- 2009-04-05 IL IL197946A patent/IL197946A0/en unknown
- 2009-04-05 IL IL197947A patent/IL197947A0/en unknown
- 2009-04-27 MA MA31821A patent/MA30814B1/fr unknown
- 2009-04-27 MA MA31824A patent/MA30817B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2665105A1 (en) | 2008-04-10 |
| CN101541316A (zh) | 2009-09-23 |
| EP2089000A2 (en) | 2009-08-19 |
| RU2009116933A (ru) | 2010-11-10 |
| US20100098735A1 (en) | 2010-04-22 |
| AU2007303794A1 (en) | 2008-04-10 |
| MX2009003737A (es) | 2009-06-16 |
| EP2086505A2 (en) | 2009-08-12 |
| CA2665101A1 (en) | 2008-04-10 |
| WO2008041246A3 (en) | 2008-05-29 |
| JP2010505819A (ja) | 2010-02-25 |
| WO2008041245A2 (en) | 2008-04-10 |
| MA30817B1 (fr) | 2009-10-01 |
| CN101541313A (zh) | 2009-09-23 |
| IL197946A0 (en) | 2009-12-24 |
| JP2010505821A (ja) | 2010-02-25 |
| WO2008041246A2 (en) | 2008-04-10 |
| BRPI0718288A2 (pt) | 2013-11-19 |
| MA30814B1 (fr) | 2009-10-01 |
| US20100015195A1 (en) | 2010-01-21 |
| KR20090087441A (ko) | 2009-08-17 |
| WO2008041245A3 (en) | 2008-05-22 |
| EA200970348A1 (ru) | 2009-10-30 |
| CL2007002851A1 (es) | 2008-01-18 |
| TN2009000124A1 (en) | 2010-10-18 |
| AR063120A1 (es) | 2008-12-30 |
| IL197947A0 (en) | 2009-12-24 |
| KR20090094811A (ko) | 2009-09-08 |
| AU2007303793A1 (en) | 2008-04-10 |
| TN2009000125A1 (en) | 2010-10-18 |
| BRPI0720346A2 (pt) | 2014-06-24 |
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