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MX2009003092A - Composiciones y metodos para suministro de farmaco dirigido a ph. - Google Patents

Composiciones y metodos para suministro de farmaco dirigido a ph.

Info

Publication number
MX2009003092A
MX2009003092A MX2009003092A MX2009003092A MX2009003092A MX 2009003092 A MX2009003092 A MX 2009003092A MX 2009003092 A MX2009003092 A MX 2009003092A MX 2009003092 A MX2009003092 A MX 2009003092A MX 2009003092 A MX2009003092 A MX 2009003092A
Authority
MX
Mexico
Prior art keywords
compositions
methods
drug delivery
targeted drug
pharmaceutically active
Prior art date
Application number
MX2009003092A
Other languages
English (en)
Inventor
Damon Smith
David Lessard
Laibin Luo
Dorothee Le Garrec
Original Assignee
Labopharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labopharm Inc filed Critical Labopharm Inc
Publication of MX2009003092A publication Critical patent/MX2009003092A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F297/00—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
    • C08F297/02—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type
    • C08F297/026—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type polymerising acrylic acid, methacrylic acid or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invención proporciona composiciones y método para suministro dirigido, en especial dirigido a pH, de agentes activos farmacéuticamente en mamíferos. Las composiciones comprenden copolímeros de doble bloque sensibles a pH, que permiten la liberación de un agente farmacéuticamente activo cuando es expuesto a un ambiente que tiene un pH particular mayor. Las composiciones son particularmente útiles para el suministro oral de agentes farmacéuticamente activos insolubles en agua.
MX2009003092A 2006-09-22 2007-09-24 Composiciones y metodos para suministro de farmaco dirigido a ph. MX2009003092A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84635506P 2006-09-22 2006-09-22
PCT/IB2007/004171 WO2008035229A2 (en) 2006-09-22 2007-09-24 Compositions and methods for ph targeted drug delivery

Publications (1)

Publication Number Publication Date
MX2009003092A true MX2009003092A (es) 2009-05-08

Family

ID=39153921

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003092A MX2009003092A (es) 2006-09-22 2007-09-24 Composiciones y metodos para suministro de farmaco dirigido a ph.

Country Status (10)

Country Link
US (1) US20090258071A1 (es)
EP (1) EP2081548A2 (es)
JP (1) JP2010504318A (es)
KR (1) KR20090080046A (es)
AU (1) AU2007298674A1 (es)
BR (1) BRPI0716890A2 (es)
CA (1) CA2699184A1 (es)
IL (1) IL197680A0 (es)
MX (1) MX2009003092A (es)
WO (1) WO2008035229A2 (es)

Families Citing this family (7)

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US20060198891A1 (en) 2004-11-29 2006-09-07 Francois Ravenelle Solid formulations of liquid biologically active agents
CA2635187A1 (en) 2008-06-05 2009-12-05 The Royal Institution For The Advancement Of Learning/Mcgill University Oligonucleotide duplexes and uses thereof
FR2932485A1 (fr) * 2008-06-12 2009-12-18 Univ Pasteur Polymere a liberation colique specifique quel que soit le ph
WO2011119995A2 (en) 2010-03-26 2011-09-29 Cerulean Pharma Inc. Formulations and methods of use
EP2563349A4 (en) * 2010-04-23 2014-03-19 Paladin Labs Inc Non-intravenous dosage form comprising solid formulation of liquid biologically active agent and uses thereof
CN102675500B (zh) * 2011-03-07 2015-05-13 深圳英利华生物技术有限公司 利用有机镁试剂制备高分子负载有机锡化合物的方法及应用
US12194113B2 (en) 2018-02-06 2025-01-14 Solventum Intellectual Properties Company Microcapsule with a porous or hollow core and ph-sensitive shell and use thereof

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Also Published As

Publication number Publication date
EP2081548A2 (en) 2009-07-29
WO2008035229A2 (en) 2008-03-27
IL197680A0 (en) 2009-12-24
US20090258071A1 (en) 2009-10-15
BRPI0716890A2 (pt) 2013-10-22
CA2699184A1 (en) 2008-03-27
JP2010504318A (ja) 2010-02-12
WO2008035229A3 (en) 2009-08-13
AU2007298674A1 (en) 2008-03-27
KR20090080046A (ko) 2009-07-23

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