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MX2009003081A - Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas. - Google Patents

Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas.

Info

Publication number
MX2009003081A
MX2009003081A MX2009003081A MX2009003081A MX2009003081A MX 2009003081 A MX2009003081 A MX 2009003081A MX 2009003081 A MX2009003081 A MX 2009003081A MX 2009003081 A MX2009003081 A MX 2009003081A MX 2009003081 A MX2009003081 A MX 2009003081A
Authority
MX
Mexico
Prior art keywords
cytokine
treatment
mediated diseases
derivatives useful
pyrrole derivatives
Prior art date
Application number
MX2009003081A
Other languages
English (en)
Inventor
Richard Heng
Achim Schlapbach
Max Peter Seiler
Guido Koch
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009003081A publication Critical patent/MX2009003081A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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  • Health & Medical Sciences (AREA)
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  • Pain & Pain Management (AREA)
  • Hematology (AREA)
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  • Cardiology (AREA)
  • Dermatology (AREA)
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Abstract

Un compuesto de la Fórmula (I) o una sal farmacéuticamente aceptable o un éster de profármaco del mismo, donde los grupos R1-R6 y A son como se definen en la especificación.
MX2009003081A 2006-09-21 2007-09-19 Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas. MX2009003081A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06121036 2006-09-21
PCT/EP2007/008153 WO2008034600A1 (en) 2006-09-21 2007-09-19 Pyrrole derivatives useful for the treatment of cytokine-mediated diseases

Publications (1)

Publication Number Publication Date
MX2009003081A true MX2009003081A (es) 2009-04-01

Family

ID=37684420

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003081A MX2009003081A (es) 2006-09-21 2007-09-19 Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas.

Country Status (11)

Country Link
US (1) US20100105664A1 (es)
EP (1) EP2069333A1 (es)
JP (1) JP2010504295A (es)
KR (1) KR20090057032A (es)
CN (1) CN101516874A (es)
AU (1) AU2007299261A1 (es)
BR (1) BRPI0717097A2 (es)
CA (1) CA2662359A1 (es)
MX (1) MX2009003081A (es)
RU (1) RU2009114747A (es)
WO (1) WO2008034600A1 (es)

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WO2011101865A2 (en) 2010-02-19 2011-08-25 Cadila Healthcare Limited Stable pharmaceutical compositions of clopidogrel for parenteral delivery
EP2970193B1 (en) * 2013-03-12 2018-07-25 AbbVie Inc. Pyrrole amide inhibitors
US9566087B2 (en) 2013-03-15 2017-02-14 Access Scientific, Llc Vascular access device
PL3013796T3 (pl) 2013-06-27 2020-06-15 Lg Chem, Ltd. Pochodne biarylowe jako agoniści gpr120
JP2017505787A (ja) * 2014-02-14 2017-02-23 ザ ユニバーシティ オブ ブリティッシュ コロンビア 治療薬としてのヒトアンドロゲン受容体ｄｎａ結合ドメイン（ｄｂｄ）化合物およびそれらを使用する方法
AU2015367977B9 (en) * 2014-12-24 2020-02-06 Lg Chem, Ltd Biaryl derivative as GPR120 agonist
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