MX2009003065A - Formulacion efervescente de ibuprofeno con alto indice de disolucion y proceso para su preparacion. - Google Patents
Formulacion efervescente de ibuprofeno con alto indice de disolucion y proceso para su preparacion.Info
- Publication number
- MX2009003065A MX2009003065A MX2009003065A MX2009003065A MX2009003065A MX 2009003065 A MX2009003065 A MX 2009003065A MX 2009003065 A MX2009003065 A MX 2009003065A MX 2009003065 A MX2009003065 A MX 2009003065A MX 2009003065 A MX2009003065 A MX 2009003065A
- Authority
- MX
- Mexico
- Prior art keywords
- ibuprofen
- production
- dissolution rate
- high dissolution
- effervescent preparation
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000004090 dissolution Methods 0.000 title 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 2
- 239000008187 granular material Substances 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000012752 auxiliary agent Substances 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 229960001680 ibuprofen Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Formulaciones efervescentes de ibuprofeno, que contienen (a) un gránulo que contiene ingrediente activo que contiene una sal de ibuprofeno soluble en agua y un excipiente básico, y (b) un gránulo efervescente que contiene un componente ácido y un componente que forma dióxido de carbono, y un proceso para su preparación.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06121278A EP1905428A1 (de) | 2006-09-26 | 2006-09-26 | Ibuprofen-Brausezubereitung mit hoher Lösungsgeschwindigkeit und Verfahren zu deren Herstellung |
| PCT/EP2007/059043 WO2008037555A1 (de) | 2006-09-26 | 2007-08-30 | Ibuprofen-brausezuberξitung mit hoher lösungsgeschwindigkeit und verfahren zu deren herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009003065A true MX2009003065A (es) | 2009-05-28 |
Family
ID=37775689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009003065A MX2009003065A (es) | 2006-09-26 | 2007-08-30 | Formulacion efervescente de ibuprofeno con alto indice de disolucion y proceso para su preparacion. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20100172981A1 (es) |
| EP (2) | EP1905428A1 (es) |
| JP (1) | JP2010504366A (es) |
| KR (1) | KR20090074784A (es) |
| CN (1) | CN101534797B (es) |
| AT (1) | ATE438387T1 (es) |
| AU (1) | AU2007302161A1 (es) |
| BR (1) | BRPI0717084A2 (es) |
| CA (1) | CA2664420A1 (es) |
| CO (1) | CO6180421A2 (es) |
| DE (1) | DE502007001262D1 (es) |
| DK (1) | DK2061436T3 (es) |
| EC (1) | ECSP099200A (es) |
| ES (1) | ES2331438T3 (es) |
| IL (1) | IL197309A0 (es) |
| MX (1) | MX2009003065A (es) |
| NZ (1) | NZ575183A (es) |
| PL (1) | PL2061436T3 (es) |
| PT (1) | PT2061436E (es) |
| RU (1) | RU2478381C2 (es) |
| WO (1) | WO2008037555A1 (es) |
| ZA (1) | ZA200901478B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1863460B1 (en) | 2005-03-22 | 2013-01-16 | Losan Pharma GmbH | Solubilized ibuprofen |
| KR101683293B1 (ko) * | 2009-06-29 | 2016-12-06 | 라이온 가부시키가이샤 | 경구용 조성물 |
| JP5663238B2 (ja) * | 2009-08-31 | 2015-02-04 | ライオン株式会社 | 内服固形製剤及びその製造方法 |
| CN102100686A (zh) * | 2009-12-21 | 2011-06-22 | 北京润德康医药技术有限公司 | 一种含有布洛芬与精氨酸的药用组合物及其制备方法、用途 |
| CN102743366B (zh) * | 2012-07-16 | 2013-11-20 | 海南葫芦娃制药有限公司 | 对乙酰氨基酚泡腾颗粒及其鉴别方法 |
| BR112017005362A2 (pt) | 2014-09-17 | 2018-01-23 | Steerlife India Private Ltd | composição, forma de dosagem sólida oral, processo para preparação de grânulos efervescentes porosos, processador de parafuso duplo, e, grânulos efervescentes porosos. |
| WO2017098481A1 (en) | 2015-12-12 | 2017-06-15 | Steerlife India Private Limited | Effervescent compositions of metformin and processes for preparation thereof |
| FR3055800B1 (fr) | 2016-09-15 | 2020-06-26 | Unither Pharmaceuticals | Composition solide a ingestion rapide et deglutition facilitee, sous forme de particules solides non agglomerees, comprenant deux differents types de particules |
| JP6836375B2 (ja) * | 2016-11-21 | 2021-03-03 | 花王株式会社 | 口腔内発泡製剤及びその製造法 |
| GB2595301B (en) * | 2020-05-21 | 2025-01-08 | Reckitt Benckiser Health Ltd | Novel Formulation |
| GB2595300B (en) * | 2020-05-21 | 2024-03-27 | Reckitt Benckiser Health Ltd | Novel Formulation |
| GB2595453B (en) * | 2020-05-21 | 2024-04-03 | Reckitt Benckiser Health Ltd | Novel Formulation |
| US20230292992A1 (en) * | 2022-03-18 | 2023-09-21 | CapsoVision, Inc. | Apparatus for Thermally Stable Capsule Endoscope Using Effervescent Formulation for Controlling Balloon Inflation Rate |
| WO2023182904A1 (ru) * | 2022-03-21 | 2023-09-28 | Акционерное Общество "Производственная Фармацевтическая Компания Обновление" | Шипучий лекарственный препарат для приготовления раствора, способ его изготовления |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1209667B (it) | 1985-11-12 | 1989-08-30 | Zambon Spa | Composizione effeverscente adattivita' analgesica. |
| CH677606A5 (es) * | 1988-07-12 | 1991-06-14 | Aesculapius Pharma Sa | |
| DE3838431A1 (de) * | 1988-11-12 | 1990-05-17 | Bayer Ag | Ibuprofen-brausezubereitungen |
| CH684929A5 (de) * | 1992-11-19 | 1995-02-15 | Sipharm Sisseln Ag | Ibuprofen-haltige Brausezusammensetzung und ihre Herstellung. |
| EP0667149A1 (en) * | 1994-02-14 | 1995-08-16 | E-PHARMA TRENTO S.p.A. | Ibuprofen based effervescent composition |
| US5639475A (en) * | 1995-02-03 | 1997-06-17 | Eurand America, Incorporated | Effervescent microcapsules |
| DE19606151C2 (de) * | 1996-02-20 | 1999-05-12 | Losan Pharma Gmbh | Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben |
| GB9816899D0 (en) * | 1998-08-05 | 1998-09-30 | Boots Co Plc | Therapeutic agents |
| EP1589944B1 (de) * | 2003-02-06 | 2011-11-23 | Gebro Pharma GmbH | Pharmazeutische zubereitungen und verfahren zu deren herstellung |
| WO2006002836A1 (de) * | 2004-07-01 | 2006-01-12 | Losan Pharma Gmbh | Brausezusammensetzungen von einschlafmitteln |
| EP1863460B1 (en) * | 2005-03-22 | 2013-01-16 | Losan Pharma GmbH | Solubilized ibuprofen |
| WO2006120281A1 (en) | 2005-05-12 | 2006-11-16 | Perlos Oyj | Optical signal processing device |
-
2006
- 2006-09-26 EP EP06121278A patent/EP1905428A1/de not_active Withdrawn
-
2007
- 2007-08-30 DE DE502007001262T patent/DE502007001262D1/de active Active
- 2007-08-30 DK DK07803052T patent/DK2061436T3/da active
- 2007-08-30 JP JP2009529640A patent/JP2010504366A/ja active Pending
- 2007-08-30 RU RU2009107536/15A patent/RU2478381C2/ru not_active IP Right Cessation
- 2007-08-30 PL PL07803052T patent/PL2061436T3/pl unknown
- 2007-08-30 CN CN2007800358397A patent/CN101534797B/zh not_active Expired - Fee Related
- 2007-08-30 BR BRPI0717084-0A2A patent/BRPI0717084A2/pt not_active IP Right Cessation
- 2007-08-30 AT AT07803052T patent/ATE438387T1/de active
- 2007-08-30 KR KR1020097008554A patent/KR20090074784A/ko not_active Ceased
- 2007-08-30 WO PCT/EP2007/059043 patent/WO2008037555A1/de not_active Ceased
- 2007-08-30 AU AU2007302161A patent/AU2007302161A1/en not_active Abandoned
- 2007-08-30 MX MX2009003065A patent/MX2009003065A/es active IP Right Grant
- 2007-08-30 PT PT07803052T patent/PT2061436E/pt unknown
- 2007-08-30 EP EP07803052A patent/EP2061436B1/de active Active
- 2007-08-30 US US12/443,107 patent/US20100172981A1/en not_active Abandoned
- 2007-08-30 ES ES07803052T patent/ES2331438T3/es active Active
- 2007-08-30 CA CA002664420A patent/CA2664420A1/en not_active Abandoned
- 2007-08-30 NZ NZ575183A patent/NZ575183A/en not_active IP Right Cessation
-
2009
- 2009-02-26 IL IL197309A patent/IL197309A0/en unknown
- 2009-03-02 ZA ZA200901478A patent/ZA200901478B/xx unknown
- 2009-03-20 CO CO09029370A patent/CO6180421A2/es not_active Application Discontinuation
- 2009-03-20 EC EC2009009200A patent/ECSP099200A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010504366A (ja) | 2010-02-12 |
| EP2061436A1 (de) | 2009-05-27 |
| AU2007302161A1 (en) | 2008-04-03 |
| ATE438387T1 (de) | 2009-08-15 |
| ECSP099200A (es) | 2009-06-30 |
| DE502007001262D1 (de) | 2009-09-17 |
| KR20090074784A (ko) | 2009-07-07 |
| EP2061436B1 (de) | 2009-08-05 |
| EP1905428A1 (de) | 2008-04-02 |
| PT2061436E (pt) | 2009-10-30 |
| IL197309A0 (en) | 2009-12-24 |
| CN101534797A (zh) | 2009-09-16 |
| US20100172981A1 (en) | 2010-07-08 |
| RU2009107536A (ru) | 2010-11-20 |
| CA2664420A1 (en) | 2008-04-03 |
| ZA200901478B (en) | 2010-03-31 |
| NZ575183A (en) | 2012-03-30 |
| PL2061436T3 (pl) | 2009-12-31 |
| CN101534797B (zh) | 2012-03-28 |
| ES2331438T3 (es) | 2010-01-04 |
| DK2061436T3 (da) | 2009-11-02 |
| CO6180421A2 (es) | 2010-07-19 |
| BRPI0717084A2 (pt) | 2013-10-29 |
| RU2478381C2 (ru) | 2013-04-10 |
| WO2008037555A1 (de) | 2008-04-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2009003065A (es) | Formulacion efervescente de ibuprofeno con alto indice de disolucion y proceso para su preparacion. | |
| WO2008075081A3 (en) | Composition and method for detection of demineralisation | |
| TNSN07452A1 (en) | Stabile active ingredient complex of salts of the o-acetylsalicylic acid with basic amino acids and glycine | |
| WO2003088923A3 (en) | Methods of treating ileus | |
| IL185031A0 (en) | Method for the preparation of pregabalin and salts thereof | |
| TW200745261A (en) | Aqueous dispersions based on nitrocellulose-polyurethane particles | |
| WO2006122223A3 (en) | Strategies for delivery of active agents using micelles and particles | |
| MX2010009222A (es) | Soluciones farmaceuticas, proceso de preparacion y usos terapeuticos. | |
| WO2008064202A3 (en) | Modified-release formulations of calcium receptor-active compounds | |
| WO2006131591A3 (en) | An entacapone-containing oral dosage form | |
| WO2007112366A3 (en) | Animal product enrichment using resveratrol | |
| WO2008128775A3 (en) | Stabilised pharmaceutical composition containing pregabaline | |
| IN2015DN03936A (es) | ||
| WO2008003050A3 (en) | Gallium nitrate formulations | |
| MX2012006954A (es) | Proceso para la preparacion de compuestos quelados. | |
| WO2008051539A3 (en) | Processes for preparing palonosetron salts | |
| MY146596A (en) | A tablet having improved stability with at least two actives | |
| WO2011131370A8 (en) | Melt-granulated fingolimod | |
| WO2006118884A3 (en) | Drug delivery devices and related components, systems and methods | |
| WO2011155728A3 (ko) | 골다공증 예방 또는 치료용 조성물 및 이의 제조방법 | |
| WO2011127244A8 (en) | ATAZANAVIR SULFATE FORMULATIONS WITH IMPROVED pH EFFECT | |
| MXPA05008902A (es) | Soluciones de drogas en mentol. | |
| WO2007098924A3 (de) | Zusammensetzung umfassend ein mittel zum stabilisieren von wirkstoffen im trinkwasser und eine brausemischung, verfahren zu deren herstellung und deren verwendung | |
| MX2011006721A (es) | Formulacion farmaceutica de fenofibrato nanonizado. | |
| WO2009120844A3 (en) | Pharmaceutical compositions comprising insulin sensitizer and insulin secretagogue |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |