MX2009001235A - Composicion y uso de un gel oral endoparasiticida bioadhesivo de larga accion a base de doramectina. - Google Patents
Composicion y uso de un gel oral endoparasiticida bioadhesivo de larga accion a base de doramectina.Info
- Publication number
- MX2009001235A MX2009001235A MX2009001235A MX2009001235A MX2009001235A MX 2009001235 A MX2009001235 A MX 2009001235A MX 2009001235 A MX2009001235 A MX 2009001235A MX 2009001235 A MX2009001235 A MX 2009001235A MX 2009001235 A MX2009001235 A MX 2009001235A
- Authority
- MX
- Mexico
- Prior art keywords
- present
- doramectin
- oral
- endoparasiticide
- compositions known
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La presente invención se refiere a la composición de un gel bioadhesivo endoparasiticida a base de doramectina, con un alto nivel de adhesión a la mucosa oral equina y con un sabor dulce que facilita enormemente su dosificación, a procedimientos para su preparación y a su utilización. La helmintosis gastrointestinal es una afección parasitaria causada por nemátodos de diversas familias que ocasionan importantes trastornos gastrointestinales en el ganada equino. El control de esta enfermedad es de gran importancia y favorablemente alcanzable mediante el empleo de agentes antihelmínticos adecuados tales como la doramectina, que es un compuesto químico administrado ampliamente por la vía parenteral y poco frecuentemente por la vía oral en forma líquida debido a las características organolépticas y fisicoquímicas de las composiciones conocidas hasta la fecha. La presente invención demuestra que es posible administrar doramectina bajo la forma farmacéutica de gel oral, a concentraciones de hasta 5,0% peso/volumen, superando las limitantes organolépticas y fisicoquímicas de la composiciones conocidas hasta la fecha. Factores, nunca antes incluidos en composiciones endoparasiticidas orales a base de doramectina, que presentan una amplia ventaja diferencial frente a las composiciones conocidas a la fecha. Estas y otras características, objetivos y ventajas de la presente invención serán apreciadas por los expertos en la materia a partir de la descripción detallada expuesta más adelante en el presente documento, así como en las reivindicaciones adjuntas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PE0015512008 | 2008-09-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009001235A true MX2009001235A (es) | 2010-04-29 |
Family
ID=42039956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009001235A MX2009001235A (es) | 2008-09-19 | 2009-01-30 | Composicion y uso de un gel oral endoparasiticida bioadhesivo de larga accion a base de doramectina. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8455452B2 (es) |
| EP (1) | EP2345413A4 (es) |
| CN (1) | CN102202671A (es) |
| AU (1) | AU2009294293A1 (es) |
| BR (1) | BRPI0913753B1 (es) |
| CA (1) | CA2737671A1 (es) |
| CR (1) | CR20110207A (es) |
| EA (1) | EA022209B1 (es) |
| MX (1) | MX2009001235A (es) |
| PE (1) | PE20100713A1 (es) |
| WO (1) | WO2010032113A2 (es) |
| ZA (1) | ZA201102793B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013137748A1 (en) * | 2012-03-13 | 2013-09-19 | Bayer New Zealand Limited | Long acting compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPN933396A0 (en) * | 1996-04-17 | 1996-05-09 | Pfizer Pty Limited | Non-aqueuos oral-drench compositions containing avermectin compounds |
| AU707949C (en) | 1996-07-30 | 2006-01-19 | Merial, Inc. | Anthelmintic formulations |
| GB9827727D0 (en) * | 1998-12-16 | 1999-02-10 | Pfizer Ltd | Antiparasitic formulations |
| US6893652B2 (en) | 2001-08-27 | 2005-05-17 | Wyeth | Endoparasiticidal gel composition |
| PT2347654T (pt) * | 2001-09-17 | 2019-05-30 | Elanco Us Inc | Formulação para o controlo de piolhos ou carrapatos em bovinos |
| US7001889B2 (en) * | 2002-06-21 | 2006-02-21 | Merial Limited | Anthelmintic oral homogeneous veterinary pastes |
| US20080027011A1 (en) * | 2005-12-20 | 2008-01-31 | Hassan Nached | Homogeneous paste and gel formulations |
-
2009
- 2009-01-30 MX MX2009001235A patent/MX2009001235A/es active IP Right Grant
- 2009-08-28 PE PE2010000469A patent/PE20100713A1/es active IP Right Grant
- 2009-08-28 WO PCT/IB2009/006867 patent/WO2010032113A2/es not_active Ceased
- 2009-08-28 CN CN2009801368925A patent/CN102202671A/zh active Pending
- 2009-08-28 EP EP09814154.2A patent/EP2345413A4/en not_active Withdrawn
- 2009-08-28 BR BRPI0913753A patent/BRPI0913753B1/pt not_active IP Right Cessation
- 2009-08-28 EA EA201170470A patent/EA022209B1/ru not_active IP Right Cessation
- 2009-08-28 US US13/062,419 patent/US8455452B2/en not_active Expired - Fee Related
- 2009-08-28 CA CA2737671A patent/CA2737671A1/en not_active Abandoned
- 2009-08-28 AU AU2009294293A patent/AU2009294293A1/en not_active Abandoned
-
2011
- 2011-04-14 ZA ZA2011/02793A patent/ZA201102793B/en unknown
- 2011-04-25 CR CR20110207A patent/CR20110207A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US8455452B2 (en) | 2013-06-04 |
| CR20110207A (es) | 2011-09-06 |
| US20110160155A1 (en) | 2011-06-30 |
| BRPI0913753A2 (pt) | 2015-10-20 |
| EA201170470A1 (ru) | 2011-10-31 |
| EP2345413A4 (en) | 2013-11-20 |
| PE20100713A1 (es) | 2010-10-13 |
| CN102202671A (zh) | 2011-09-28 |
| WO2010032113A2 (es) | 2010-03-25 |
| CA2737671A1 (en) | 2010-03-25 |
| EP2345413A2 (en) | 2011-07-20 |
| EA022209B1 (ru) | 2015-11-30 |
| WO2010032113A3 (es) | 2010-06-17 |
| ZA201102793B (en) | 2011-12-28 |
| AU2009294293A1 (en) | 2010-03-25 |
| BRPI0913753B1 (pt) | 2018-07-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |