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MX2009000871A - Novedosos inhibidores de transcriptasa inversa de vih. - Google Patents

Novedosos inhibidores de transcriptasa inversa de vih.

Info

Publication number
MX2009000871A
MX2009000871A MX2009000871A MX2009000871A MX2009000871A MX 2009000871 A MX2009000871 A MX 2009000871A MX 2009000871 A MX2009000871 A MX 2009000871A MX 2009000871 A MX2009000871 A MX 2009000871A MX 2009000871 A MX2009000871 A MX 2009000871A
Authority
MX
Mexico
Prior art keywords
reverse transcriptase
transcriptase inhibitors
hiv reverse
novel hiv
compounds
Prior art date
Application number
MX2009000871A
Other languages
English (en)
Inventor
Choung U Kim
Lianhong Xu
Hongyan Guo
Young Lee Iii
Michael L Mitchell
Jong Chan Son
Thorsten A Kirschberg
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of MX2009000871A publication Critical patent/MX2009000871A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se refiere a compuestos de la Fórmula (I), (II), o (III): (ver fórmulas (I), (II)) y (Ill)) o a una sal farmacéuticamente aceptable, solvato, éster, y/o fosfonato de los mismos, a composiciones que contienen estos compuestos, y a métodos terapéuticos que incluyen la administración de tales compuestos.
MX2009000871A 2006-07-24 2007-07-24 Novedosos inhibidores de transcriptasa inversa de vih. MX2009000871A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83280606P 2006-07-24 2006-07-24
PCT/US2007/016703 WO2008016522A2 (en) 2006-07-24 2007-07-24 Hiv reverse transcriptase inhibitors

Publications (1)

Publication Number Publication Date
MX2009000871A true MX2009000871A (es) 2009-05-08

Family

ID=38997642

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009000871A MX2009000871A (es) 2006-07-24 2007-07-24 Novedosos inhibidores de transcriptasa inversa de vih.

Country Status (18)

Country Link
US (2) US20100034827A1 (es)
EP (1) EP2044037A2 (es)
JP (1) JP2009544710A (es)
KR (2) KR20110089463A (es)
CN (1) CN101495461A (es)
AP (1) AP2514A (es)
AU (1) AU2007281604A1 (es)
BR (1) BRPI0714880A2 (es)
CA (1) CA2658479A1 (es)
EA (1) EA200900213A1 (es)
HR (1) HRP20090114A2 (es)
IL (1) IL196675A0 (es)
MX (1) MX2009000871A (es)
NO (1) NO20090835L (es)
NZ (1) NZ573793A (es)
SG (1) SG174016A1 (es)
UA (1) UA95955C2 (es)
WO (1) WO2008016522A2 (es)

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Also Published As

Publication number Publication date
KR20090040449A (ko) 2009-04-24
CA2658479A1 (en) 2008-02-07
US8106064B2 (en) 2012-01-31
IL196675A0 (en) 2009-11-18
KR20110089463A (ko) 2011-08-08
CN101495461A (zh) 2009-07-29
WO2008016522A2 (en) 2008-02-07
US20080070920A1 (en) 2008-03-20
JP2009544710A (ja) 2009-12-17
NO20090835L (no) 2009-04-23
HRP20090114A2 (hr) 2010-03-31
BRPI0714880A2 (pt) 2013-05-21
NZ573793A (en) 2012-01-12
US20100034827A1 (en) 2010-02-11
AP2514A (en) 2012-11-23
EA200900213A1 (ru) 2009-06-30
WO2008016522A3 (en) 2008-12-11
SG174016A1 (en) 2011-09-29
AU2007281604A1 (en) 2008-02-07
AP2009004759A0 (en) 2009-02-28
EP2044037A2 (en) 2009-04-08
UA95955C2 (ru) 2011-09-26

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