MX2008013017A - Tratamiento de malignidades hematologicas con fts y un inhibidor de tirosina cinasa de bcr-abl. - Google Patents
Tratamiento de malignidades hematologicas con fts y un inhibidor de tirosina cinasa de bcr-abl.Info
- Publication number
- MX2008013017A MX2008013017A MX2008013017A MX2008013017A MX2008013017A MX 2008013017 A MX2008013017 A MX 2008013017A MX 2008013017 A MX2008013017 A MX 2008013017A MX 2008013017 A MX2008013017 A MX 2008013017A MX 2008013017 A MX2008013017 A MX 2008013017A
- Authority
- MX
- Mexico
- Prior art keywords
- fts
- bcr
- abl
- kinase inhibitor
- hematological
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Están descritos métodos para tratar una malignidad hematológica mediante administrar a un humano que necesita de las mismas cantidades efectivas de FTS (Ácido Farnesiltiosalicilico), o varios análogos del mismo, o una sal farmacéuticamente aceptable del mismo, opcionalmente en combinación con un inhibidor de tirosina cinasa de Bcr-Abl. También están descritas composiciones farmacéuticas que comprende FTS, o varios análogos del mismo, o una sal farmacéuticamente aceptable del mismo, un inhibidor de tirosina cinasa de Bcr-Abl, preferiblemente Imatinib y un portador farmacéuticamente aceptable.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79105006P | 2006-04-11 | 2006-04-11 | |
| PCT/IL2007/000439 WO2007116396A1 (en) | 2006-04-11 | 2007-04-10 | Treatment of hematological malignancies with fts and a bcr-abl tyrosine kinase inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008013017A true MX2008013017A (es) | 2008-11-27 |
Family
ID=38218987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008013017A MX2008013017A (es) | 2006-04-11 | 2007-04-10 | Tratamiento de malignidades hematologicas con fts y un inhibidor de tirosina cinasa de bcr-abl. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090298843A1 (es) |
| EP (1) | EP2004170A1 (es) |
| CA (1) | CA2648518C (es) |
| MX (1) | MX2008013017A (es) |
| WO (1) | WO2007116396A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007064448A2 (en) | 2005-11-28 | 2007-06-07 | Ramot At Tel Aviv University, Ltd. | Cancer treatment using fts and 2-deoxyglucose |
| JP2013508450A (ja) * | 2009-10-26 | 2013-03-07 | ラモット・アット・テル−アヴィヴ・ユニヴァーシティ・リミテッド | Ｆｔｓおよびそのアナログによる甲状腺がん治療のための組成物 |
| JP2013508458A (ja) * | 2009-10-26 | 2013-03-07 | ラモット・アット・テル−アヴィヴ・ユニヴァーシティ・リミテッド | Ｆｔｓとｈｄａｃ阻害剤との組合せを用いたがん治療 |
| EP2763681B1 (en) | 2011-10-07 | 2017-08-16 | Pisces Therapeutics LLC | Malignant and non-malignant disease treatment with ras antagonists |
| US9738614B2 (en) | 2011-10-07 | 2017-08-22 | Pisces Therapeutics, Llc | Malignant and non-malignant disease treatment with Ras antagonists |
| GB201311891D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compound |
| GB201311888D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| US20180228907A1 (en) | 2014-04-14 | 2018-08-16 | Arvinas, Inc. | Cereblon ligands and bifunctional compounds comprising the same |
| CN108366992A (zh) * | 2015-11-02 | 2018-08-03 | 耶鲁大学 | 蛋白水解靶向嵌合体化合物及其制备和应用方法 |
| CN112218859B (zh) | 2018-04-04 | 2024-10-29 | 阿尔维纳斯运营股份有限公司 | 蛋白水解调节剂及相关使用方法 |
| IL322247A (en) | 2023-01-26 | 2025-09-01 | Arvinas Operations Inc | Cerebellon-based KRAS-disrupting proteins and related uses |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5202456A (en) * | 1991-04-15 | 1993-04-13 | The President And Fellows Of Harvard College | Compounds for inhibition of protein methylation |
| IL107587A (en) * | 1993-11-12 | 1998-08-16 | Univ Ramot | Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation |
| EP1187605A4 (en) * | 1999-06-18 | 2004-05-26 | Thyreos Corp | TREATMENT OF NON-MALIGNANT CONDITIONS WITH RAS ANTAGONISTS |
| WO2004004644A2 (en) * | 2002-07-05 | 2004-01-15 | Beth Israel Deaconess Medical Center | Combination of mtor inhibitor and a tyrosine kinase inhibitor for the treatment of neoplasms |
-
2007
- 2007-04-10 US US12/225,944 patent/US20090298843A1/en not_active Abandoned
- 2007-04-10 EP EP07736179A patent/EP2004170A1/en not_active Withdrawn
- 2007-04-10 WO PCT/IL2007/000439 patent/WO2007116396A1/en not_active Ceased
- 2007-04-10 MX MX2008013017A patent/MX2008013017A/es unknown
- 2007-04-10 CA CA2648518A patent/CA2648518C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2648518A1 (en) | 2007-10-18 |
| WO2007116396A1 (en) | 2007-10-18 |
| CA2648518C (en) | 2012-06-26 |
| US20090298843A1 (en) | 2009-12-03 |
| EP2004170A1 (en) | 2008-12-24 |
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