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MX2008012705A - Cocristal de derivado de c-glucosido y l-prolina. - Google Patents

Cocristal de derivado de c-glucosido y l-prolina.

Info

Publication number
MX2008012705A
MX2008012705A MX2008012705A MX2008012705A MX2008012705A MX 2008012705 A MX2008012705 A MX 2008012705A MX 2008012705 A MX2008012705 A MX 2008012705A MX 2008012705 A MX2008012705 A MX 2008012705A MX 2008012705 A MX2008012705 A MX 2008012705A
Authority
MX
Mexico
Prior art keywords
cocrystal
proline
glycoside derivative
benzothien
excelling
Prior art date
Application number
MX2008012705A
Other languages
English (en)
Inventor
Ryota Shiraki
Kenichi Onda
Daisuke Sasuga
Masakazu Imamura
Keita Nakanishi
Masamichi Yuda
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38563736&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2008012705(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of MX2008012705A publication Critical patent/MX2008012705A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un cocristal de (1S)-1,5-anhidro-1-[3-(1-benzotien-2-ilmetil)-4-fl uorofenil]-D-glucitol y L-prolina. Esta cocristal asegura una calidad constante, sobresaliente en estabilidad en almacenamiento, y no exhibe ninguna absorbencia de humedad, siendo un cocristal del compuesto conocido (A) siendo adecuado como un cristal de un fármaco puro para terminarse en productos farmacéuticos.
MX2008012705A 2006-04-05 2007-04-04 Cocristal de derivado de c-glucosido y l-prolina. MX2008012705A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006103711 2006-04-05
PCT/JP2007/057597 WO2007114475A1 (ja) 2006-04-05 2007-04-04 Ｃ－グリコシド誘導体とｌ－プロリンとの共結晶

Publications (1)

Publication Number Publication Date
MX2008012705A true MX2008012705A (es) 2008-10-15

Family

ID=38563736

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008012705A MX2008012705A (es) 2006-04-05 2007-04-04 Cocristal de derivado de c-glucosido y l-prolina.

Country Status (15)

Country Link
US (1) US8097592B2 (es)
EP (1) EP2009010A4 (es)
JP (1) JP5210154B2 (es)
KR (2) KR20120025001A (es)
CN (1) CN101443328B (es)
AU (1) AU2007232763B2 (es)
BR (1) BRPI0710581A2 (es)
CA (1) CA2649022C (es)
IL (1) IL194512A0 (es)
MX (1) MX2008012705A (es)
NO (1) NO20084659L (es)
RU (1) RU2408595C2 (es)
TW (1) TWI370818B (es)
WO (1) WO2007114475A1 (es)
ZA (1) ZA200809201B (es)

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Also Published As

Publication number Publication date
EP2009010A4 (en) 2012-06-13
CN101443328B (zh) 2012-07-25
RU2408595C2 (ru) 2011-01-10
EP2009010A1 (en) 2008-12-31
JPWO2007114475A1 (ja) 2009-08-20
TWI370818B (en) 2012-08-21
KR101243039B1 (ko) 2013-03-20
US20090143316A1 (en) 2009-06-04
KR20120025001A (ko) 2012-03-14
CN101443328A (zh) 2009-05-27
BRPI0710581A2 (pt) 2011-08-16
AU2007232763B2 (en) 2011-07-28
WO2007114475A1 (ja) 2007-10-11
CA2649022A1 (en) 2007-10-11
RU2008143362A (ru) 2010-05-10
KR20090015912A (ko) 2009-02-12
AU2007232763A1 (en) 2007-10-11
JP5210154B2 (ja) 2013-06-12
IL194512A0 (en) 2009-08-03
US8097592B2 (en) 2012-01-17
ZA200809201B (en) 2009-12-30
CA2649022C (en) 2012-05-29
TW200811152A (en) 2008-03-01
NO20084659L (no) 2009-01-02

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