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MX2008009219A - Elementos de control de expresion de la familia lemnaceae. - Google Patents

Elementos de control de expresion de la familia lemnaceae.

Info

Publication number
MX2008009219A
MX2008009219A MX2008009219A MX2008009219A MX2008009219A MX 2008009219 A MX2008009219 A MX 2008009219A MX 2008009219 A MX2008009219 A MX 2008009219A MX 2008009219 A MX2008009219 A MX 2008009219A MX 2008009219 A MX2008009219 A MX 2008009219A
Authority
MX
Mexico
Prior art keywords
interest
control elements
expression control
signal peptide
lemnaceae
Prior art date
Application number
MX2008009219A
Other languages
English (en)
Inventor
Lynn F Dickey
Kevin M Cox
Charles G Peele
Original Assignee
Biolex Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolex Therapeutics Inc filed Critical Biolex Therapeutics Inc
Publication of MX2008009219A publication Critical patent/MX2008009219A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8221Transit peptides
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8222Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8222Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
    • C12N15/8223Vegetative tissue-specific promoters
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8237Externally regulated expression systems
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2434Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2442Chitinase (3.2.1.14)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
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    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01014Chitinase (3.2.1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • C12Y401/01039Ribulose-bisphosphate carboxylase (4.1.1.39)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se proporcionan composiciones y métodos para regular la expresión de las secuencias de nucleótido de interés en una planta. Las composiciones incluyen novedosas moléculas de ácido nucleico y variantes y fragmentos de las mismas, para los elementos de control de expresión aislados de los genes de la ubiquitia de Lemnaceae, la r-histona y la quinatasa. Se proporciona además un método para expresar una secuencia de nucleótido de interés en una planta usando los elementos de control de expresión divulgados en el presente documento. También se proporciona una novedosa secuencia de codificación del péptido de señal de Lemnaceae y la señal de péptido codificada mediante la misma. Cuando una construcción de expresión de la invención está diseñada para expresar un polipéptido de interés, esta novedosa secuencia de codificación del péptido de señal puede ser incluida dentro de la construcción de expresión de la invención para proporcionar una secreción extracelular del polipéptido codificado de interés.
MX2008009219A 2006-01-17 2007-01-17 Elementos de control de expresion de la familia lemnaceae. MX2008009219A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75930806P 2006-01-17 2006-01-17
US84896106P 2006-10-03 2006-10-03
PCT/US2007/060614 WO2007124186A2 (en) 2006-01-17 2007-01-17 Expression control elements from the lemnaceae family

Publications (1)

Publication Number Publication Date
MX2008009219A true MX2008009219A (es) 2008-09-30

Family

ID=38625682

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008009219A MX2008009219A (es) 2006-01-17 2007-01-17 Elementos de control de expresion de la familia lemnaceae.

Country Status (12)

Country Link
US (2) US7622573B2 (es)
EP (2) EP2325197A3 (es)
JP (1) JP2009523431A (es)
KR (1) KR20080094914A (es)
AU (1) AU2007240573B2 (es)
BR (1) BRPI0707291A2 (es)
CA (1) CA2637222A1 (es)
ES (1) ES2398142T3 (es)
IL (1) IL192760A0 (es)
MX (1) MX2008009219A (es)
RU (1) RU2008133627A (es)
WO (1) WO2007124186A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7622573B2 (en) * 2006-01-17 2009-11-24 Biolex, Inc. Expression control elements from the lemnaceae family
WO2010138631A1 (en) 2009-05-26 2010-12-02 Biolex Therapeutics, Inc. Compositions and methods for production of aglycosylated plasminogen
WO2012174139A2 (en) 2011-06-14 2012-12-20 Synthon Biopharmaceuticals B.V. Compositions and methods for making and b ioc ont aining auxotrophic transgenic plants
EP2791172B1 (en) 2011-12-16 2017-07-19 Synthon Biopharmaceuticals B.V. Compounds and methods for treating inflammatory diseases
CA2915960A1 (en) 2013-06-17 2014-12-24 Asana Biosciences, Llc 5t4-targeted immunofusion molecule and methods
CN106834433A (zh) * 2016-12-05 2017-06-13 浙江海洋大学 利用特异性引物对紫背浮萍Sp10微卫星标记检测的方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
US4761373A (en) 1984-03-06 1988-08-02 Molecular Genetics, Inc. Herbicide resistance in plants
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
WO1987004181A1 (en) 1986-01-08 1987-07-16 Rhone-Poulenc Agrochimie Haloarylnitrile degrading gene, its use, and cells containing the same
US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
US5316931A (en) 1988-02-26 1994-05-31 Biosource Genetics Corp. Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes
CA1339684C (en) 1988-05-17 1998-02-24 Peter H. Quail Plant ubquitin promoter system
US5990387A (en) 1988-06-10 1999-11-23 Pioneer Hi-Bred International, Inc. Stable transformation of plant cells
NZ230375A (en) 1988-09-09 1991-07-26 Lubrizol Genetics Inc Synthetic gene encoding b. thuringiensis insecticidal protein
DK0413019T3 (da) 1989-02-24 2001-11-12 Monsanto Technology Llc Syntetiske plantegener og fremgangsmåde til fremstilling af disse
US5879918A (en) 1989-05-12 1999-03-09 Pioneer Hi-Bred International, Inc. Pretreatment of microprojectiles prior to using in a particle gun
US5202422A (en) 1989-10-27 1993-04-13 The Scripps Research Institute Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use
EP0452269B1 (en) 1990-04-12 2002-10-09 Syngenta Participations AG Tissue-preferential promoters
CA2080584C (en) 1990-04-18 2000-09-05 Marc Cornelissen Modified bacillus thuringiensis insecticidal-crystal protein genes and their expression in plant cells
US5932782A (en) 1990-11-14 1999-08-03 Pioneer Hi-Bred International, Inc. Plant transformation method using agrobacterium species adhered to microprojectiles
TW261517B (es) 1991-11-29 1995-11-01 Mitsubishi Shozi Kk
EP0652965A1 (en) 1992-07-27 1995-05-17 Pioneer Hi-Bred International, Inc. An improved method of agrobacterium-mediated transformation of cultured soybean cells
IL108241A (en) 1992-12-30 2000-08-13 Biosource Genetics Corp Plant expression system comprising a defective tobamovirus replicon integrated into the plant chromosome and a helper virus
FR2712302B1 (fr) 1993-11-10 1996-01-05 Rhone Poulenc Agrochimie Eléments promoteurs de gènes chimères de tubuline alpha.
US6020169A (en) 1995-07-20 2000-02-01 Washington State University Research Foundation Production of secreted foreign polypeptides in plant cell culture
US6072050A (en) 1996-06-11 2000-06-06 Pioneer Hi-Bred International, Inc. Synthetic promoters
US5981840A (en) 1997-01-24 1999-11-09 Pioneer Hi-Bred International, Inc. Methods for agrobacterium-mediated transformation
WO1999007210A1 (en) * 1997-08-12 1999-02-18 North Carolina State University Genetically engineered duckweed
US6040498A (en) 1998-08-11 2000-03-21 North Caroline State University Genetically engineered duckweed
US6528701B1 (en) 1999-03-02 2003-03-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Rice ubiquitin-derived promoters
CA2403909A1 (en) * 2000-03-27 2001-10-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
AU2001288226B2 (en) 2000-07-31 2007-07-26 Synthon Biopharmaceuticals B.V. Expression of biologically active polypeptides in duckweed
EP1397676B1 (en) * 2001-05-30 2009-12-30 Biolex Therapeutics, Inc. Use of duckweed in high throughput screening
DE10224889A1 (de) 2002-06-04 2003-12-18 Metanomics Gmbh & Co Kgaa Verfahren zur stabilen Expression von Nukleinsäuren in transgenen Pflanzen
RU2006102864A (ru) * 2003-07-01 2006-06-10 Биолекс, Инк. (Us) Трансформация хлоропластов ряски
BRPI0507613A (pt) * 2004-02-11 2007-07-03 Biolex Inc expressão de plasminogênio e microplasminogênio em lentilha d'água
US7622573B2 (en) * 2006-01-17 2009-11-24 Biolex, Inc. Expression control elements from the lemnaceae family
NZ596322A (en) * 2006-01-17 2013-02-22 Synthon Biopharmaceuticals Bv Compositions and methods for humanization and optimization of N-glycans in duckweed plants

Also Published As

Publication number Publication date
ES2398142T3 (es) 2013-03-13
US20070180583A1 (en) 2007-08-02
HK1115389A1 (en) 2008-11-28
BRPI0707291A2 (pt) 2011-04-26
US7622573B2 (en) 2009-11-24
EP2325197A3 (en) 2011-07-27
RU2008133627A (ru) 2010-02-27
EP2325197A2 (en) 2011-05-25
US8034916B2 (en) 2011-10-11
EP1973935A2 (en) 2008-10-01
JP2009523431A (ja) 2009-06-25
IL192760A0 (en) 2009-02-11
AU2007240573B2 (en) 2012-11-08
AU2007240573A1 (en) 2007-11-01
US20100043099A1 (en) 2010-02-18
WO2007124186A3 (en) 2008-04-24
CA2637222A1 (en) 2007-11-01
WO2007124186A2 (en) 2007-11-01
EP1973935B1 (en) 2012-10-10
KR20080094914A (ko) 2008-10-27

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