MX2008008079A - Hibridación genómica comparativa sobre partículas múltiples codificadas. - Google Patents
Hibridación genómica comparativa sobre partículas múltiples codificadas.Info
- Publication number
- MX2008008079A MX2008008079A MX2008008079A MX2008008079A MX2008008079A MX 2008008079 A MX2008008079 A MX 2008008079A MX 2008008079 A MX2008008079 A MX 2008008079A MX 2008008079 A MX2008008079 A MX 2008008079A MX 2008008079 A MX2008008079 A MX 2008008079A
- Authority
- MX
- Mexico
- Prior art keywords
- particles
- mixture
- particle
- sample
- different
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 11
- 238000009396 hybridization Methods 0.000 title abstract 4
- 230000000052 comparative effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 6
- 239000000523 sample Substances 0.000 abstract 5
- 238000012544 monitoring process Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
La descripción presente pertenece a un método para evaluar DNA genómico que comprende los pasos de: a) disponer de una muestra de DNA genómico; b) disponer de una mezcla de partículas, la mezcla contiene partículas de diferentes series de partículas, en donde cada serie de partículas contiene numerosas partículas codificadas y una sonda de hibridación ácido nucleico para el locus genómico particular, de modo que la mezcla colectivamente incluye sondas para una pluralidad de diferentes loci genómicos; c) poner en contacto la muestra a una porción de la muestra de partículas en condiciones de hibridación; y d) evaluar la hibridación de la muestra a partículas en la porción respectiva de la mezcla mediante la monitorización de una etiqueta detectable, en donde las señales de la monitorización son indicativas del número de copias de cada locus genómico interrogado. La invención además pertenece a una mezcla de partículas que contiene partículas de diferentes series de partículas de ésta.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75382205P | 2005-12-23 | 2005-12-23 | |
| US75358405P | 2005-12-23 | 2005-12-23 | |
| US76535506P | 2006-02-03 | 2006-02-03 | |
| US76531106P | 2006-02-03 | 2006-02-03 | |
| PCT/US2006/048801 WO2007075894A2 (en) | 2005-12-23 | 2006-12-22 | Comparative genomic hybridization on encoded multiplex particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008008079A true MX2008008079A (es) | 2008-10-22 |
Family
ID=38218614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008008079A MX2008008079A (es) | 2005-12-23 | 2006-12-22 | Hibridación genómica comparativa sobre partículas múltiples codificadas. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20070166739A1 (es) |
| EP (2) | EP1969142B1 (es) |
| JP (4) | JP6148428B2 (es) |
| CN (1) | CN101384732B (es) |
| AU (1) | AU2006331607B2 (es) |
| BR (1) | BRPI0620420B1 (es) |
| CA (1) | CA2634447C (es) |
| MX (1) | MX2008008079A (es) |
| WO (1) | WO2007075894A2 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7709544B2 (en) | 2005-10-25 | 2010-05-04 | Massachusetts Institute Of Technology | Microstructure synthesis by flow lithography and polymerization |
| US7932037B2 (en) | 2007-12-05 | 2011-04-26 | Perkinelmer Health Sciences, Inc. | DNA assays using amplicon probes on encoded particles |
| US20090104613A1 (en) * | 2005-12-23 | 2009-04-23 | Perkinelmer Las, Inc. | Methods and compositions relating to multiplexed genomic gain and loss assays |
| US20100009373A1 (en) * | 2005-12-23 | 2010-01-14 | Perkinelmer Health Sciences, Inc. | Methods and compositions relating to multiplex genomic gain and loss assays |
| EP2069788B1 (en) * | 2006-10-05 | 2017-03-01 | Massachusetts Institute of Technology | Multifunctional encoded particles for high-throughput analysis |
| JP5504587B2 (ja) * | 2008-05-27 | 2014-05-28 | 東レ株式会社 | 分析用チップ |
| KR101932628B1 (ko) | 2010-06-07 | 2018-12-27 | 파이어플라이 바이오웍스, 인코포레이티드 | 후혼성 표지화 및 범용 코드화에 의한 핵산 검출 및 정량화 |
| US9568425B2 (en) * | 2011-02-01 | 2017-02-14 | Dna Medicine Institute, Inc. | Multicoded analytical nanostrips |
| US20140342469A1 (en) * | 2011-11-10 | 2014-11-20 | Kowa Company, Ltd. | Method for measuring physiologically active substance of biological origin |
| US11391735B2 (en) * | 2017-09-06 | 2022-07-19 | AimPlex Biosciences, Inc. | Methods for improving the dynamic range of biological assays |
| WO2022032195A2 (en) | 2020-08-06 | 2022-02-10 | Singular Genomics Systems, Inc. | Spatial sequencing |
| US11492662B2 (en) | 2020-08-06 | 2022-11-08 | Singular Genomics Systems, Inc. | Methods for in situ transcriptomics and proteomics |
| WO2022235764A1 (en) | 2021-05-05 | 2022-11-10 | Singular Genomics Systems, Inc. | Multiomic analysis device and methods of use thereof |
| WO2024249961A1 (en) | 2023-06-01 | 2024-12-05 | Singular Genomics Systems, Inc. | Methods and probes for detecting polynucleotide sequences in cells and tissues |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US508545A (en) * | 1893-11-14 | Administratrix op isaac | ||
| US563535A (en) | 1896-07-07 | Paul a | ||
| US4310408A (en) * | 1980-02-20 | 1982-01-12 | Mcdonnell Douglas Corporation | Electrophoresis chamber |
| US4499052A (en) * | 1982-08-30 | 1985-02-12 | Becton, Dickinson And Company | Apparatus for distinguishing multiple subpopulations of cells |
| SE458968B (sv) | 1987-06-16 | 1989-05-22 | Wallac Oy | Biospecifikt analysfoerfarande foer flera analyter i vilket ingaar partikelraekning och maerkning med fluorescerande maerksubstanser |
| US5670314A (en) * | 1994-02-22 | 1997-09-23 | Regents Of The University Of California | Genetic alterations that correlate with lung carcinomas |
| US5830645A (en) * | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
| US5635351A (en) * | 1995-03-14 | 1997-06-03 | The Regents Of The University Of California | Genetic gain and loss in gliomas |
| US5926387A (en) | 1995-06-30 | 1999-07-20 | Beckman Instruments, Inc. | Ultracentrifuge operation by computer system |
| US5981180A (en) | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
| EP1736554B1 (en) * | 1996-05-29 | 2013-10-09 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions |
| US6277563B1 (en) | 1997-01-16 | 2001-08-21 | The Regents Of The University Of California | Genetic alterations associated with cancer |
| IL131332A (en) * | 1997-02-12 | 2003-07-31 | Eugene Y Chan | Methods and products for analyzing polymers |
| US6048695A (en) | 1998-05-04 | 2000-04-11 | Baylor College Of Medicine | Chemically modified nucleic acids and methods for coupling nucleic acids to solid support |
| US6268147B1 (en) * | 1998-11-02 | 2001-07-31 | Kenneth Loren Beattie | Nucleic acid analysis using sequence-targeted tandem hybridization |
| JP3628614B2 (ja) * | 1999-03-15 | 2005-03-16 | アプレラ コーポレイション | 多重核酸検出のためのプローブ/移動度モディファイア複合体 |
| AU6779700A (en) | 1999-08-17 | 2001-03-13 | Luminex Corporation | Microparticles with multiple fluorescent signals and methods of using same |
| KR100385714B1 (ko) * | 1999-12-31 | 2003-05-27 | 에스케이케미칼주식회사 | 안정화된 이소티아졸론 용액 및 이소티아졸론의 안정화 방법 |
| US6500622B2 (en) * | 2000-03-22 | 2002-12-31 | Quantum Dot Corporation | Methods of using semiconductor nanocrystals in bead-based nucleic acid assays |
| WO2001086296A2 (en) * | 2000-05-05 | 2001-11-15 | Agilix Corporation | Highly multiplexed reporter carrier systems |
| US20030082549A1 (en) * | 2000-08-30 | 2003-05-01 | Xiangjun Liu | Method for determining alleles |
| AU2002351193A1 (en) * | 2001-11-28 | 2003-06-10 | Mj Bioworks Incorporated | Parallel polymorphism scoring by amplification and error correction |
| US20030224385A1 (en) * | 2001-12-07 | 2003-12-04 | German Pihan | Targeted genetic risk-stratification using microarrays |
| CN1389539A (zh) * | 2002-06-18 | 2003-01-08 | 高明远 | 纳米微粒、微球及其生物荧光探针的制备和应用 |
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| WO2004019277A1 (en) | 2002-08-20 | 2004-03-04 | Cyvera Corporation | Diffraction grating-based encoded micro-particles for multiplexed experiments |
| CA2498916A1 (en) | 2002-09-12 | 2004-03-25 | Cyvera Corporation | Chemical synthesis using diffraction grating-based encoded optical elements |
| EP1540591A1 (en) | 2002-09-12 | 2005-06-15 | Cyvera Corporation | Diffraction grating-based encoded micro-particles for multiplexed experiments |
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| WO2007022530A2 (en) * | 2005-08-16 | 2007-02-22 | The Children's Mercy Hospital | Quantification of microsphere suspension hybridization and uses thereof |
| MX2008007626A (es) * | 2005-11-18 | 2009-03-04 | Childrens Mercy Hospital | Mitigacion de la distorsion de adn de cont-1 en hibridizacion de acido nucleo. |
| CN102851369B (zh) * | 2006-12-13 | 2015-01-21 | 卢米耐克斯公司 | 用于实时pcr多重分析的系统和方法 |
-
2006
- 2006-12-22 BR BRPI0620420A patent/BRPI0620420B1/pt not_active IP Right Cessation
- 2006-12-22 WO PCT/US2006/048801 patent/WO2007075894A2/en not_active Ceased
- 2006-12-22 MX MX2008008079A patent/MX2008008079A/es active IP Right Grant
- 2006-12-22 EP EP06845950.2A patent/EP1969142B1/en active Active
- 2006-12-22 AU AU2006331607A patent/AU2006331607B2/en active Active
- 2006-12-22 EP EP12159372.7A patent/EP2508622B1/en active Active
- 2006-12-22 CN CN200680053334.9A patent/CN101384732B/zh active Active
- 2006-12-22 JP JP2008547548A patent/JP6148428B2/ja active Active
- 2006-12-22 US US11/615,739 patent/US20070166739A1/en not_active Abandoned
- 2006-12-22 CA CA2634447A patent/CA2634447C/en active Active
-
2012
- 2012-10-01 JP JP2012219508A patent/JP2012254099A/ja not_active Withdrawn
-
2015
- 2015-04-14 JP JP2015082211A patent/JP2015128453A/ja active Pending
-
2016
- 2016-04-21 JP JP2016085005A patent/JP2016136967A/ja active Pending
-
2018
- 2018-12-30 US US16/236,599 patent/US20190376123A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007075894A2 (en) | 2007-07-05 |
| JP2009521221A (ja) | 2009-06-04 |
| JP2012254099A (ja) | 2012-12-27 |
| US20190376123A1 (en) | 2019-12-12 |
| JP6148428B2 (ja) | 2017-06-14 |
| EP2508622A3 (en) | 2013-01-09 |
| EP1969142B1 (en) | 2018-02-14 |
| CA2634447A1 (en) | 2007-07-05 |
| BRPI0620420B1 (pt) | 2016-08-09 |
| EP1969142A2 (en) | 2008-09-17 |
| JP2015128453A (ja) | 2015-07-16 |
| EP2508622A2 (en) | 2012-10-10 |
| US20070166739A1 (en) | 2007-07-19 |
| EP1969142A4 (en) | 2010-01-06 |
| CN101384732A (zh) | 2009-03-11 |
| CA2634447C (en) | 2018-12-18 |
| CN101384732B (zh) | 2015-11-25 |
| JP2016136967A (ja) | 2016-08-04 |
| AU2006331607A1 (en) | 2007-07-05 |
| WO2007075894A3 (en) | 2008-01-31 |
| EP2508622B1 (en) | 2016-09-14 |
| BRPI0620420A2 (pt) | 2011-11-08 |
| AU2006331607B2 (en) | 2012-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |