MX2007011975A - Mimeticuerpos de peptido similar a glucagon-1 humanos, composiciones, metodos y usos. - Google Patents
Mimeticuerpos de peptido similar a glucagon-1 humanos, composiciones, metodos y usos.Info
- Publication number
- MX2007011975A MX2007011975A MX2007011975A MX2007011975A MX2007011975A MX 2007011975 A MX2007011975 A MX 2007011975A MX 2007011975 A MX2007011975 A MX 2007011975A MX 2007011975 A MX2007011975 A MX 2007011975A MX 2007011975 A MX2007011975 A MX 2007011975A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- glp
- compositions
- mimetibody
- mimetibodies
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 101100337060 Caenorhabditis elegans glp-1 gene Proteins 0.000 title 1
- 101710198884 GATA-type zinc finger protein 1 Proteins 0.000 abstract 2
- 102100025101 GATA-type zinc finger protein 1 Human genes 0.000 abstract 2
- DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 abstract 2
- 101000788682 Homo sapiens GATA-type zinc finger protein 1 Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invencion se refiere por lo menos a un novedoso mimeticuerpo de peptido-glucagonoide-1 humano (GLP-1) o porcion o variante especificada, incluyendo acidos nucleicos aislados que codifican por lo menos un mimeticuetpo GLP-1 o porcion o variante especificada, mimeticuerpo GLP-1 o porcion o variantes, vectores, celulas hospederas, animales o plantas transgenicos especificados, y metodos de elaborar y usar los mismos incluyendo composiciones, metodos y dispositivos terapeuticos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2005097175 | 2005-03-28 | ||
| PCT/US2005/046884 WO2007081302A2 (en) | 2005-03-28 | 2005-12-22 | Human glp-1 mimetibodies, compositions, methods and uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007011975A true MX2007011975A (es) | 2008-03-14 |
Family
ID=38256744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007011975A MX2007011975A (es) | 2005-03-28 | 2005-12-22 | Mimeticuerpos de peptido similar a glucagon-1 humanos, composiciones, metodos y usos. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1871811A4 (es) |
| JP (1) | JP2008546373A (es) |
| KR (1) | KR20080005378A (es) |
| CN (1) | CN101389346A (es) |
| AU (1) | AU2005339797A1 (es) |
| BR (1) | BRPI0520168A2 (es) |
| CA (1) | CA2603359A1 (es) |
| CR (1) | CR9481A (es) |
| IL (1) | IL186307A0 (es) |
| MX (1) | MX2007011975A (es) |
| NO (1) | NO20075272L (es) |
| WO (1) | WO2007081302A2 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200843794A (en) | 2006-12-21 | 2008-11-16 | Centocor Inc | Use of long-acting GLP-1 receptor agonists to improve insulin sensitivity and lipid profiles |
| CN111574583B (zh) * | 2020-04-10 | 2021-06-25 | 上海海路生物技术有限公司 | 蛋白复性试剂及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6656728B1 (en) * | 1999-02-08 | 2003-12-02 | Chiron Corporation | Fibroblast growth factor receptor-immunoglobulin fusion |
| IL155812A0 (en) * | 2000-12-07 | 2003-12-23 | Lilly Co Eli | Glp-1 fusion proteins |
| JP2005536992A (ja) * | 2002-06-28 | 2005-12-08 | セントカー・インコーポレーテツド | 哺乳動物のｅｐｏ模倣ｃｈ１欠失ミメティボディ、組成物、方法および使用 |
| CA2490409A1 (en) * | 2002-06-28 | 2004-01-08 | Centocor, Inc. | Mammalian ch1 deleted mimetibodies, compositions, methods and uses |
| WO2005005604A2 (en) * | 2003-06-30 | 2005-01-20 | Centocor, Inc. | Engineered anti-target immunoglobulin derived proteins, compositions, methods and uses |
| KR20070004078A (ko) * | 2004-03-31 | 2007-01-05 | 센토코 인코포레이티드 | 인간 ｇｌｐ-1 모방체, 조성물, 방법 및 용도 |
-
2005
- 2005-12-22 EP EP05858723A patent/EP1871811A4/en not_active Withdrawn
- 2005-12-22 JP JP2008504018A patent/JP2008546373A/ja active Pending
- 2005-12-22 WO PCT/US2005/046884 patent/WO2007081302A2/en not_active Ceased
- 2005-12-22 CN CNA200580049931XA patent/CN101389346A/zh active Pending
- 2005-12-22 KR KR1020077024874A patent/KR20080005378A/ko not_active Withdrawn
- 2005-12-22 MX MX2007011975A patent/MX2007011975A/es not_active Application Discontinuation
- 2005-12-22 BR BRPI0520168-3A patent/BRPI0520168A2/pt not_active Application Discontinuation
- 2005-12-22 AU AU2005339797A patent/AU2005339797A1/en not_active Abandoned
- 2005-12-22 CA CA002603359A patent/CA2603359A1/en not_active Abandoned
-
2007
- 2007-09-25 IL IL186307A patent/IL186307A0/en unknown
- 2007-10-15 NO NO20075272A patent/NO20075272L/no not_active Application Discontinuation
- 2007-10-29 CR CR9481A patent/CR9481A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20075272L (no) | 2007-12-28 |
| EP1871811A2 (en) | 2008-01-02 |
| BRPI0520168A2 (pt) | 2009-04-22 |
| CN101389346A (zh) | 2009-03-18 |
| EP1871811A4 (en) | 2009-07-22 |
| WO2007081302A2 (en) | 2007-07-19 |
| CR9481A (es) | 2009-01-14 |
| AU2005339797A1 (en) | 2007-07-19 |
| JP2008546373A (ja) | 2008-12-25 |
| IL186307A0 (en) | 2008-01-20 |
| KR20080005378A (ko) | 2008-01-11 |
| WO2007081302A3 (en) | 2008-11-13 |
| CA2603359A1 (en) | 2007-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |