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MX2007008195A - Sintesis de copolimeros de bloque hibridos y usos de los mismos. - Google Patents

Sintesis de copolimeros de bloque hibridos y usos de los mismos.

Info

Publication number
MX2007008195A
MX2007008195A MX2007008195A MX2007008195A MX2007008195A MX 2007008195 A MX2007008195 A MX 2007008195A MX 2007008195 A MX2007008195 A MX 2007008195A MX 2007008195 A MX2007008195 A MX 2007008195A MX 2007008195 A MX2007008195 A MX 2007008195A
Authority
MX
Mexico
Prior art keywords
synthesis
block copolymers
hybrid block
hybrid
preparing
Prior art date
Application number
MX2007008195A
Other languages
English (en)
Inventor
Kevin N Sill
Kurt E Ii Breitenkamp
Original Assignee
Intezyne Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intezyne Technologies Llc filed Critical Intezyne Technologies Llc
Publication of MX2007008195A publication Critical patent/MX2007008195A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0233Polyamines derived from (poly)oxazolines, (poly)oxazines or having pendant acyl groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F297/00Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/028Polyamidoamines
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/08Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Polyamides (AREA)
  • Graft Or Block Polymers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion se refiere al campo de la quimica de polimero y mas particularmente a copolimeros de bloque multiple y metodos para preparar los mismos.
MX2007008195A 2005-01-04 2006-01-04 Sintesis de copolimeros de bloque hibridos y usos de los mismos. MX2007008195A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64117005P 2005-01-04 2005-01-04
PCT/US2006/000144 WO2006074202A2 (en) 2005-01-04 2006-01-04 Synthesis of hybrid block copolymers and uses thereof

Publications (1)

Publication Number Publication Date
MX2007008195A true MX2007008195A (es) 2008-02-22

Family

ID=36648126

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007008195A MX2007008195A (es) 2005-01-04 2006-01-04 Sintesis de copolimeros de bloque hibridos y usos de los mismos.

Country Status (9)

Country Link
US (2) US7601796B2 (es)
EP (3) EP1833958A4 (es)
JP (1) JP5086099B2 (es)
AU (1) AU2006204067B2 (es)
CA (1) CA2594240C (es)
IL (1) IL184384A (es)
MX (1) MX2007008195A (es)
NZ (3) NZ588064A (es)
WO (1) WO2006074202A2 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601796B2 (en) * 2005-01-04 2009-10-13 Intezyne Technologies, Inc. Synthesis of hybrid block copolymers and uses thereof
CA2597378A1 (en) * 2005-02-11 2006-08-17 Intezyne Technologies, Incorporated Synthesis of homopolymers and block copolymers
CA2603853C (en) 2005-04-01 2013-11-19 Intezyne Technologies, Incorporated Polymeric micelles for drug delivery
EP2010475A2 (en) 2006-04-27 2009-01-07 Intezyne Technologies Incorporated Heterofunctional poly(ethylene glycol) containing acid-labile amino protecting groups and uses thereof
WO2007127473A2 (en) 2006-04-27 2007-11-08 Intezyne Technologies, Inc. Poly (ethylene glycol) containing chemically disparate endgroups
WO2008006097A2 (en) * 2006-07-07 2008-01-10 Intezyne Technologies Llc Covalent modification of metal surfaces
WO2008070284A2 (en) 2006-10-16 2008-06-12 Johnnie B. Byrd, Sr. Alzheimer's Center And Research Institute Amyloid beta peptides and methods of uses thereof
US7618944B2 (en) * 2007-03-01 2009-11-17 Intezyne Technologies, Inc. Encapsulated amyloid-beta peptides
ES2432641T3 (es) 2007-04-30 2013-12-04 Intezyne Technologies Inc. Micelas híbridas de copolímero en bloque con estereoquímica mixta para encapsulación de agentes hidrófobos
WO2008134734A2 (en) * 2007-04-30 2008-11-06 Intezyne Technologies, Inc. Encapsulated contrast agents
US20090047517A1 (en) * 2007-06-27 2009-02-19 Francesco Caruso Multilayer polymer films
US20090286938A1 (en) * 2008-04-30 2009-11-19 Intezyne Technologies, Inc. Synthesis of hybrid block copolymers from difluoroacetate ammonium salts
US8524784B2 (en) 2009-04-30 2013-09-03 Intezyne Technologies, Incorporated Polymer micelles containing anthracylines for the treatment of cancer
WO2010127154A1 (en) * 2009-04-30 2010-11-04 Intezyne Technologies, Incorporated Polymers for polynucleotide encapsulation
US8524783B2 (en) 2009-04-30 2013-09-03 Intezyne Technologies, Incorporated Polymer micelles containing anthracylines for the treatment of cancer
KR20120112383A (ko) 2009-10-16 2012-10-11 바스프 에스이 폴리이소부텐 블록 및 올리고아미드 블록으로 제조된 열가소성 엘라스토머로서의 블록 공중합체
US20110256227A1 (en) * 2010-04-14 2011-10-20 Intezyne Technologies, Inc. Controlled polyplex assembly
US8609146B2 (en) 2011-09-19 2013-12-17 Intezyne Technologies, Inc. Multi-block copolymers for the preparation of stabilized micelles
US9078930B2 (en) 2012-04-11 2015-07-14 Intezyne Technologies, Inc. Block copolymers for stable micelles
US9944752B2 (en) 2012-04-11 2018-04-17 Intezyne Technologies, Inc. Block copolymers for stable micelles
CN106170334B (zh) * 2013-12-07 2019-07-09 诺沃梅尔公司 纳米过滤膜和使用方法
US10143689B2 (en) 2017-02-08 2018-12-04 Interzyne Technologies, Inc. SN-38 loaded iron crosslinked micelle and methods thereof
CN107840952B (zh) * 2017-10-24 2019-05-24 中山大学 一种pH与还原双重敏感性的纳米囊泡及其制备方法和应用
CN114206397A (zh) * 2019-08-08 2022-03-18 富鲁达加拿大公司 用于质谱流式细胞术的其它质量标签聚合物
FR3100248B1 (fr) * 2019-09-03 2022-01-07 Univ Bordeaux Procédé de préparation de polymères et copolymères contrôlés à base de peptides en solution aqueuse
CN113045752A (zh) * 2021-03-25 2021-06-29 电子科技大学 一种温敏性聚合物及其制备方法以及温敏性水凝胶
US11806405B1 (en) 2021-07-19 2023-11-07 Zeno Management, Inc. Immunoconjugates and methods
WO2023014875A2 (en) * 2021-08-04 2023-02-09 Research Foundation Of The City University Of New York Method of synthesizing a mucin and product thereof

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5238598A (en) * 1975-09-23 1977-03-25 Toray Ind Inc Modified polyamide compositions
US5516931A (en) 1982-02-01 1996-05-14 Northeastern University Release tag compounds producing ketone signal groups
US4709016A (en) 1982-02-01 1987-11-24 Northeastern University Molecular analytical release tags and their use in chemical analysis
US4650750A (en) 1982-02-01 1987-03-17 Giese Roger W Method of chemical analysis employing molecular release tag compounds
US5650270A (en) 1982-02-01 1997-07-22 Northeastern University Molecular analytical release tags and their use in chemical analysis
JPH05117385A (ja) * 1991-10-31 1993-05-14 Res Dev Corp Of Japan ブロツク共重合体の製造法、ブロツク共重合体及び水溶性高分子抗癌剤
KR940003548U (ko) * 1992-08-14 1994-02-21 김형술 세탁물 건조기
JP3268913B2 (ja) * 1992-10-27 2002-03-25 日本化薬株式会社 高分子担体
FR2708932B1 (fr) * 1993-08-10 1995-11-10 Flamel Tech Sa Procédé de préparation de polyaminoacides.
DE4434985A1 (de) * 1994-09-30 1996-04-04 Basf Ag Pfropfprodukte aus Polyethern und Maleinsäureanhydrid
FR2732218B1 (fr) * 1995-03-28 1997-08-01 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s) et leurs procedes de preparation
NZ313769A (en) * 1995-08-10 2000-02-28 Kazunori Kataoka block polymer having a functional group presented on each end
JP2694923B2 (ja) * 1995-08-21 1997-12-24 科学技術振興事業団 水溶性高分子化医薬製剤
JP3220069B2 (ja) * 1997-09-26 2001-10-22 ナノキャリア株式会社 薬物含有ポリマーミセルおよびその医薬製剤
US6686446B2 (en) * 1998-03-19 2004-02-03 The Regents Of The University Of California Methods and compositions for controlled polypeptide synthesis
US6790823B1 (en) 1998-04-23 2004-09-14 Amgen Inc. Compositions and methods for the prevention and treatment of cardiovascular diseases
JPH11335267A (ja) 1998-05-27 1999-12-07 Nano Career Kk 水難溶性薬物を含有するポリマーミセル系
US6333396B1 (en) 1998-10-20 2001-12-25 Enzon, Inc. Method for targeted delivery of nucleic acids
FR2786098B1 (fr) * 1998-11-20 2003-05-30 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
DE60041062D1 (de) * 1999-05-19 2009-01-22 Nof Corp Polymer, in vivo abbaubares material und dessen verwendung
US6413306B1 (en) * 1999-10-07 2002-07-02 E. I. Du Pont De Nemours And Company Pigment dispersions containing ABC-block polymer dispersant
JP4659937B2 (ja) * 1999-11-19 2011-03-30 ナノキャリア株式会社 コア−シェル構造のポリイオンコンプレックスミセル
DE60103092T2 (de) * 2000-02-10 2005-04-28 Nippon Shokubai Co., Ltd. Amino-Gruppe enthaltender Polymer (Salz) und dessen Herstellungsverfahren
CN100344293C (zh) * 2000-09-26 2007-10-24 株式会社东京大学Tlo 包封顺铂的高分子微胶粒及其用途
JP5005155B2 (ja) * 2000-10-06 2012-08-22 カーネギー−メロン ユニバーシティ イオンモノマーの重合方法
FR2814951B1 (fr) * 2000-10-06 2003-01-17 Flamel Tech Sa Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation
KR100446101B1 (ko) * 2000-12-07 2004-08-30 주식회사 삼양사 수난용성 약물의 서방성 제형 조성물
FR2822834B1 (fr) * 2001-04-02 2005-02-25 Flamel Tech Sa Suspension colloidale de nanoparticules a base de copolymeres amphiphile pour la vectorisation de principes actifs et leur mode de preparation
US20040126900A1 (en) * 2001-04-13 2004-07-01 Barry Stephen E High affinity peptide- containing nanoparticles
US6797257B2 (en) 2001-06-26 2004-09-28 The Board Of Trustees Of The University Of Illinois Paramagnetic polymerized protein microspheres and methods of preparation thereof
US20030147958A1 (en) * 2002-01-29 2003-08-07 Cheol-Hee Ahn Biodegradable multi-block copolymers of poly(amino acid)s and poly(ethylene glycol) for the delivery of bioactive agents
JP2004018494A (ja) * 2002-06-19 2004-01-22 Japan Science & Technology Corp ブロック共重合体−薬剤複合体の製造法
CN1185277C (zh) * 2003-03-28 2005-01-19 中国科学院长春应用化学研究所 聚乙二醇-脂肪族聚酯-聚氨基酸三元嵌段共聚物及制法
JP4535229B2 (ja) * 2003-05-08 2010-09-01 国立大学法人 東京大学 ポリエチレングリコール−ポリカチオンブロック共重合体
WO2004105799A1 (ja) 2003-05-29 2004-12-09 Toudai Tlo, Ltd. 安定化高分子ミセル
JP2006199590A (ja) * 2003-09-04 2006-08-03 Nano Career Kk 水溶性の塩基性薬物内包ナノ粒子含有組成物
CA2584510C (en) * 2004-10-25 2013-05-28 Intezyne Technologies, Incorporated Heterobifunctional poly(ethylene glycol) and uses thereof
US7601796B2 (en) 2005-01-04 2009-10-13 Intezyne Technologies, Inc. Synthesis of hybrid block copolymers and uses thereof
CA2603853C (en) 2005-04-01 2013-11-19 Intezyne Technologies, Incorporated Polymeric micelles for drug delivery
WO2006115293A1 (ja) * 2005-04-22 2006-11-02 The University Of Tokyo pH応答性高分子ミセルの調製に用いる新規ブロック共重合体及びその製造法
DE102005020815B4 (de) * 2005-05-04 2007-05-10 Applied Materials Gmbh & Co. Kg Anordnung für die Regelung der Elektronenstrahlleistung einer Elektronenstrahlkanone

Also Published As

Publication number Publication date
US20060172914A1 (en) 2006-08-03
EP2348096A2 (en) 2011-07-27
AU2006204067A1 (en) 2006-07-13
AU2006204067B2 (en) 2011-07-07
EP2348096A3 (en) 2011-11-09
NZ588064A (en) 2012-04-27
NZ556290A (en) 2010-11-26
NZ598887A (en) 2013-06-28
EP1833958A2 (en) 2007-09-19
IL184384A0 (en) 2007-10-31
JP5086099B2 (ja) 2012-11-28
CA2594240A1 (en) 2006-07-13
US8268936B2 (en) 2012-09-18
CA2594240C (en) 2013-10-15
EP2067801A1 (en) 2009-06-10
WO2006074202A3 (en) 2007-11-22
EP1833958A4 (en) 2009-01-14
US20110021718A1 (en) 2011-01-27
JP2008527092A (ja) 2008-07-24
IL184384A (en) 2013-01-31
US7601796B2 (en) 2009-10-13
WO2006074202A2 (en) 2006-07-13

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