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MX2007007790A - Conjugados y vacuna de proteina con polisacarido derivado meningococcal multivalente. - Google Patents

Conjugados y vacuna de proteina con polisacarido derivado meningococcal multivalente.

Info

Publication number
MX2007007790A
MX2007007790A MX2007007790A MX2007007790A MX2007007790A MX 2007007790 A MX2007007790 A MX 2007007790A MX 2007007790 A MX2007007790 A MX 2007007790A MX 2007007790 A MX2007007790 A MX 2007007790A MX 2007007790 A MX2007007790 A MX 2007007790A
Authority
MX
Mexico
Prior art keywords
protein conjugates
derivatized polysaccharide
polysaccharide
vaccine
derivatized
Prior art date
Application number
MX2007007790A
Other languages
English (en)
Inventor
Robert P Ryall
Original Assignee
Sanofi Pasteur Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Inc filed Critical Sanofi Pasteur Inc
Publication of MX2007007790A publication Critical patent/MX2007007790A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención describe conjugados proteínicos con polisacáridos derivados, una composición que comprende uno o más de estos conjugados proteínicos con polisacáridos derivados y los métodos para inmunizar a pacientes humanos con los mismos. Los conjugados proteínicos con polisacáridos derivados son polisacáridos capsulares purificados provenientes de los serogroups A, C, W-135, y/o y de Neisseria meningitidis, derivados químicamente, activados y unidos selectivamente a una proteína portadora por medio de un enlace químico covalente, que forma conjugados proteínicos con polisacáridos capaces de producir inmunidad por largo tiempo hacia una variedad de cepas de N. meningitidis.
MX2007007790A 2005-12-22 2005-12-22 Conjugados y vacuna de proteina con polisacarido derivado meningococcal multivalente. MX2007007790A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2005/046886 WO2007102797A2 (en) 2005-12-22 2005-12-22 Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine

Publications (1)

Publication Number Publication Date
MX2007007790A true MX2007007790A (es) 2009-06-05

Family

ID=38475284

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007007790A MX2007007790A (es) 2005-12-22 2005-12-22 Conjugados y vacuna de proteina con polisacarido derivado meningococcal multivalente.

Country Status (6)

Country Link
EP (1) EP1963522A4 (es)
JP (1) JP2009521434A (es)
CN (1) CN101443454A (es)
BR (1) BRPI0516372A (es)
MX (1) MX2007007790A (es)
WO (1) WO2007102797A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102327605B (zh) * 2011-08-25 2013-01-30 成都康华生物制品有限公司 四价脑膜炎球菌多糖疫苗的制备工艺
CN102809656B (zh) * 2012-08-26 2014-09-03 云南沃森生物技术股份有限公司 一种脑膜炎球菌多糖结合疫苗成品各群游离多糖含量的测定方法
EP3174553B1 (en) * 2014-07-25 2018-04-18 Biosynth S.R.L. Glycoconjugate vaccines comprising basic units of a molecular construct expressing multiple built-in epitopes for the formulation of a broad-spectrum vaccine against infections due to enteropathogenic bacteria
CN104383532A (zh) * 2014-12-02 2015-03-04 云南沃森生物技术股份有限公司 一种用乙肝表面抗原为载体蛋白的细菌多糖蛋白结合物疫苗及其制备方法
HRP20240433T1 (hr) 2016-09-02 2024-07-05 Sanofi Pasteur, Inc. Cjepivo protiv neisseria meningitidis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5425946A (en) * 1992-08-31 1995-06-20 North American Vaccine, Inc. Vaccines against group C Neisseria meningitidis
EP0994723A1 (en) * 1997-06-24 2000-04-26 Chiron Corporation Methods of immunizing adults using anti-meningococcal vaccine compositions
BRPI0410423A (pt) * 2003-05-07 2006-06-06 Sanofi Pasteur Inc processo de imunogenicidade melhorada para vacinação meningocócica

Also Published As

Publication number Publication date
BRPI0516372A (pt) 2008-09-02
EP1963522A2 (en) 2008-09-03
WO2007102797A2 (en) 2007-09-13
WO2007102797A3 (en) 2009-04-16
CN101443454A (zh) 2009-05-27
EP1963522A4 (en) 2010-05-12
JP2009521434A (ja) 2009-06-04

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