MX2007005525A - Therapeutic treatment of accelerated bone resorption. - Google Patents
Therapeutic treatment of accelerated bone resorption.Info
- Publication number
- MX2007005525A MX2007005525A MX2007005525A MX2007005525A MX2007005525A MX 2007005525 A MX2007005525 A MX 2007005525A MX 2007005525 A MX2007005525 A MX 2007005525A MX 2007005525 A MX2007005525 A MX 2007005525A MX 2007005525 A MX2007005525 A MX 2007005525A
- Authority
- MX
- Mexico
- Prior art keywords
- bone resorption
- accelerated bone
- therapeutic treatment
- pharmaceutical composition
- treatment
- Prior art date
Links
- 208000006386 Bone Resorption Diseases 0.000 title abstract 4
- 230000024279 bone resorption Effects 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 title 1
- 239000000556 agonist Substances 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 3
- 101150046889 ADORA3 gene Proteins 0.000 abstract 1
- 229940122614 Adenosine receptor agonist Drugs 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003379 purinergic P1 receptor agonist Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention concerns the use of an A3 adenosine receptor agonist (A3AR agonist) for treatment of accelerated bone resorption, particularly, inflammation induced bone resorption. Specifically, there is provided by the present invention a method and pharmaceutical composition for treatment of said condition, the A3AR agonist being formulated as a pharmaceutical composition which is administered to a subject having accelerated bone resorption. The invention also provides the use of A3AR agonist in the preparation of said pharmaceutical composition.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62556404P | 2004-11-08 | 2004-11-08 | |
| PCT/IL2005/001166 WO2006048884A1 (en) | 2004-11-08 | 2005-11-08 | Therapeutic treatment of accelerated bone resorption |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007005525A true MX2007005525A (en) | 2007-07-05 |
Family
ID=36001028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007005525A MX2007005525A (en) | 2004-11-08 | 2005-11-08 | Therapeutic treatment of accelerated bone resorption. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1811982A1 (en) |
| JP (1) | JP2008519029A (en) |
| KR (1) | KR20070085839A (en) |
| CN (1) | CN101072554A (en) |
| AU (1) | AU2005302090A1 (en) |
| BR (1) | BRPI0517639A (en) |
| CA (1) | CA2586845A1 (en) |
| MX (1) | MX2007005525A (en) |
| WO (1) | WO2006048884A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101101252B1 (en) * | 2005-11-30 | 2012-01-04 | 캔-파이트 바이오파마 리미티드 | Use of A3 Adenosine Receptor Agonist for the Treatment of Osteoarthritis |
| DK2137202T3 (en) | 2007-03-14 | 2017-10-02 | Can-Fite Biopharma Ltd | PROCEDURE FOR SYNTHESIS OF IB-MECA |
| WO2009061516A1 (en) * | 2007-11-08 | 2009-05-14 | New York University School Of Medicine | Medical implants containing adenosine receptor agonists and methods for inhibiting medical implant loosening |
| KR20120022919A (en) * | 2009-05-17 | 2012-03-12 | 캔-파이트 바이오파마 리미티드 | A3 adenosine receptor agonists for the reduction of intraocular pressure |
| GEP20166496B (en) | 2011-12-22 | 2016-06-27 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000072799A2 (en) * | 1999-05-27 | 2000-12-07 | The University Of Virginia Patent Foundation | Method and compositions for treating the inflammatory response |
| IL133680A0 (en) * | 1999-09-10 | 2001-04-30 | Can Fite Technologies Ltd | Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist |
| AU2003282359A1 (en) * | 2002-11-19 | 2004-06-15 | Can-Fite Biopharma Ltd. | A3ar agonists for the treatment of inflammatory arthritis |
| GB0305150D0 (en) * | 2003-03-07 | 2003-04-09 | Cambridge Biotechnology Ltd | Use of therapeutic compounds |
| MXPA06010075A (en) * | 2004-03-05 | 2007-04-10 | Cambridge Biotechnology Ltd | Therapeutic compounds. |
-
2005
- 2005-11-08 KR KR1020077012806A patent/KR20070085839A/en not_active Ceased
- 2005-11-08 MX MX2007005525A patent/MX2007005525A/en not_active Application Discontinuation
- 2005-11-08 JP JP2007539712A patent/JP2008519029A/en not_active Withdrawn
- 2005-11-08 CN CNA2005800380014A patent/CN101072554A/en active Pending
- 2005-11-08 AU AU2005302090A patent/AU2005302090A1/en not_active Abandoned
- 2005-11-08 EP EP05799989A patent/EP1811982A1/en not_active Withdrawn
- 2005-11-08 BR BRPI0517639-5A patent/BRPI0517639A/en not_active IP Right Cessation
- 2005-11-08 WO PCT/IL2005/001166 patent/WO2006048884A1/en not_active Ceased
- 2005-11-08 CA CA002586845A patent/CA2586845A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2586845A1 (en) | 2006-05-11 |
| AU2005302090A1 (en) | 2006-05-11 |
| JP2008519029A (en) | 2008-06-05 |
| KR20070085839A (en) | 2007-08-27 |
| EP1811982A1 (en) | 2007-08-01 |
| CN101072554A (en) | 2007-11-14 |
| WO2006048884A1 (en) | 2006-05-11 |
| BRPI0517639A (en) | 2008-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |