MX2007003897A - Una formulacion farmaceutica que comprende insulina cristalina e insulina disuelta. - Google Patents
Una formulacion farmaceutica que comprende insulina cristalina e insulina disuelta.Info
- Publication number
- MX2007003897A MX2007003897A MX2007003897A MX2007003897A MX2007003897A MX 2007003897 A MX2007003897 A MX 2007003897A MX 2007003897 A MX2007003897 A MX 2007003897A MX 2007003897 A MX2007003897 A MX 2007003897A MX 2007003897 A MX2007003897 A MX 2007003897A
- Authority
- MX
- Mexico
- Prior art keywords
- insulin
- pharmaceutical formulation
- dissolved
- crystalline
- crystalline insulin
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 4
- 102000004877 Insulin Human genes 0.000 title 2
- 108090001061 Insulin Proteins 0.000 title 2
- 229940125396 insulin Drugs 0.000 title 2
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invencion proporciona una formulacion farmaceutica y un metodo para preparar la formulacion.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200401519 | 2004-10-05 | ||
| PCT/EP2005/055017 WO2006037789A1 (en) | 2004-10-05 | 2005-10-05 | A pharmaceutical formulation comprising crystalline insulin and dissolved insulin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007003897A true MX2007003897A (es) | 2007-05-21 |
Family
ID=35428106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007003897A MX2007003897A (es) | 2004-10-05 | 2005-10-05 | Una formulacion farmaceutica que comprende insulina cristalina e insulina disuelta. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7884181B2 (es) |
| EP (4) | EP1802329B1 (es) |
| JP (1) | JP5080259B2 (es) |
| KR (1) | KR101238184B1 (es) |
| CN (2) | CN102772788B (es) |
| AU (1) | AU2005291233B2 (es) |
| BR (1) | BRPI0516464B8 (es) |
| CA (1) | CA2581798A1 (es) |
| CY (1) | CY1124650T1 (es) |
| DK (1) | DK2918286T3 (es) |
| ES (3) | ES2774354T3 (es) |
| HU (1) | HUE048806T2 (es) |
| LT (1) | LT2918286T (es) |
| MX (1) | MX2007003897A (es) |
| PL (2) | PL2918286T3 (es) |
| PT (1) | PT2918286T (es) |
| RU (1) | RU2389503C2 (es) |
| SI (1) | SI2918286T1 (es) |
| WO (1) | WO2006037789A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008065138A1 (en) * | 2006-11-29 | 2008-06-05 | Novo Nordisk A/S | Novel insulin crystal and method for preparing the crystal |
| CN102219851B (zh) * | 2011-05-09 | 2012-05-30 | 甘李药业有限公司 | 甘精胰岛素结晶的制备方法 |
| WO2014102623A1 (en) * | 2012-12-26 | 2014-07-03 | Wockhardt Limited | Pharmaceutical composition |
| SG11201604710XA (en) | 2014-01-09 | 2016-07-28 | Sanofi Sa | Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives |
| RU2014120626A (ru) * | 2014-05-22 | 2015-11-27 | Владимир Андреевич Сабецкий | Инсулинсодержащий препарат пролонгированного действия |
| CN105535942B (zh) * | 2016-01-28 | 2017-07-28 | 通化东宝药业股份有限公司 | 一种赖脯胰岛素硫酸鱼精蛋白制剂的制备方法及其制备的赖脯胰岛素硫酸鱼精蛋白制剂 |
| WO2017163159A1 (en) * | 2016-03-21 | 2017-09-28 | Wockhardt Limited | Biphasic pharmaceutical composition of insulin human |
| CN113248591B (zh) * | 2021-07-08 | 2021-09-28 | 北京惠之衡生物科技有限公司 | 一种门冬胰岛素结晶工艺 |
| CN113384529B (zh) * | 2021-07-08 | 2021-11-26 | 北京惠之衡生物科技有限公司 | 一种门冬胰岛素注射液及其制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB889769A (en) * | 1957-07-18 | 1962-02-21 | Nordisk Insulinlab | Slowly acting insulin preparation in crystalline form |
| DK72793D0 (da) * | 1993-06-21 | 1993-06-21 | Novo Nordisk As | Nyt produkt |
| US5474978A (en) * | 1994-06-16 | 1995-12-12 | Eli Lilly And Company | Insulin analog formulations |
| US5461031A (en) * | 1994-06-16 | 1995-10-24 | Eli Lilly And Company | Monomeric insulin analog formulations |
| US5948751A (en) * | 1996-06-20 | 1999-09-07 | Novo Nordisk A/S | X14-mannitol |
| ES2292189T3 (es) | 1996-06-20 | 2008-03-01 | Novo Nordisk A/S | Preparaciones a base de insulina conteniendo manitol. |
| US5866538A (en) * | 1996-06-20 | 1999-02-02 | Novo Nordisk A/S | Insulin preparations containing NaCl |
| RU2182015C2 (ru) | 1996-06-20 | 2002-05-10 | Ново Нордиск А/С | ПРЕПАРАТ ИНСУЛИНА, СОДЕРЖАЩИЙ NaCl, ПАРЕНТЕРАЛЬНАЯ ГОТОВАЯ ФОРМА, СПОСОБ ПОВЫШЕНИЯ ХИМИЧЕСКОЙ СТАБИЛЬНОСТИ ПРЕПАРАТА ИНСУЛИНА |
| SK2432004A3 (sk) * | 2001-12-20 | 2005-04-01 | Eli Lilly And Company | Inzulínová zlúčenina s protrahovaným účinkom |
| EP1605967A1 (en) * | 2003-03-13 | 2005-12-21 | Novo Nordisk A/S | Novel nph insulin preparations |
-
2005
- 2005-10-05 CA CA002581798A patent/CA2581798A1/en not_active Withdrawn
- 2005-10-05 MX MX2007003897A patent/MX2007003897A/es active IP Right Grant
- 2005-10-05 EP EP20050792052 patent/EP1802329B1/en not_active Expired - Lifetime
- 2005-10-05 ES ES15160523T patent/ES2774354T3/es not_active Expired - Lifetime
- 2005-10-05 EP EP20158951.2A patent/EP3689366A1/en not_active Withdrawn
- 2005-10-05 SI SI200532272T patent/SI2918286T1/sl unknown
- 2005-10-05 DK DK15161696.8T patent/DK2918286T3/da active
- 2005-10-05 LT LTEP15161696.8T patent/LT2918286T/lt unknown
- 2005-10-05 HU HUE15161696A patent/HUE048806T2/hu unknown
- 2005-10-05 CN CN201210248925.9A patent/CN102772788B/zh not_active Expired - Fee Related
- 2005-10-05 ES ES05792052.2T patent/ES2544329T3/es not_active Expired - Lifetime
- 2005-10-05 US US11/664,407 patent/US7884181B2/en active Active - Reinstated
- 2005-10-05 BR BRPI0516464A patent/BRPI0516464B8/pt not_active IP Right Cessation
- 2005-10-05 PL PL15161696T patent/PL2918286T3/pl unknown
- 2005-10-05 AU AU2005291233A patent/AU2005291233B2/en not_active Ceased
- 2005-10-05 CN CN2005800339452A patent/CN101035557B/zh not_active Expired - Fee Related
- 2005-10-05 RU RU2007111879/15A patent/RU2389503C2/ru active
- 2005-10-05 KR KR1020077007794A patent/KR101238184B1/ko not_active Expired - Fee Related
- 2005-10-05 PL PL05792052T patent/PL1802329T3/pl unknown
- 2005-10-05 EP EP15160523.5A patent/EP2926828B1/en not_active Expired - Lifetime
- 2005-10-05 WO PCT/EP2005/055017 patent/WO2006037789A1/en not_active Ceased
- 2005-10-05 PT PT151616968T patent/PT2918286T/pt unknown
- 2005-10-05 EP EP15161696.8A patent/EP2918286B1/en not_active Expired - Lifetime
- 2005-10-05 JP JP2007535163A patent/JP5080259B2/ja not_active Expired - Fee Related
- 2005-10-05 ES ES15161696T patent/ES2779957T3/es not_active Expired - Lifetime
-
2020
- 2020-03-23 CY CY20201100270T patent/CY1124650T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |