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MX2007001954A - Heterociclicos fusionados seleccionados y sus usos. - Google Patents

Heterociclicos fusionados seleccionados y sus usos.

Info

Publication number
MX2007001954A
MX2007001954A MX2007001954A MX2007001954A MX2007001954A MX 2007001954 A MX2007001954 A MX 2007001954A MX 2007001954 A MX2007001954 A MX 2007001954A MX 2007001954 A MX2007001954 A MX 2007001954A MX 2007001954 A MX2007001954 A MX 2007001954A
Authority
MX
Mexico
Prior art keywords
selected fused
fused heterocyclics
heterocyclics
novelcompounds
prophylaxis
Prior art date
Application number
MX2007001954A
Other languages
English (en)
Inventor
Brian Aquila
Michael Howard Block
Audrey Davies
Jayachandran Ezhuthachan
Timothy Pontz
Xiaolan Zheng
Daniel John Russell
Marie-Elena Theoclitou
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35004223&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2007001954(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2007001954A publication Critical patent/MX2007001954A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Esta invencion se refiere a nuevos compuestos que tienen la formula estructural (I) y a sus composiciones farmaceuticas y a sus metodos de uso. Estos nuevos compuestos proporcionan un tratamiento o profilaxis del cancer. (ver formula).
MX2007001954A 2004-08-18 2005-08-16 Heterociclicos fusionados seleccionados y sus usos. MX2007001954A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60239904P 2004-08-18 2004-08-18
PCT/GB2005/003202 WO2006018627A1 (en) 2004-08-18 2005-08-16 Selected fused heterocyclics and uses thereof

Publications (1)

Publication Number Publication Date
MX2007001954A true MX2007001954A (es) 2007-05-09

Family

ID=35004223

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007001954A MX2007001954A (es) 2004-08-18 2005-08-16 Heterociclicos fusionados seleccionados y sus usos.

Country Status (19)

Country Link
US (1) US20070249636A1 (es)
EP (1) EP1781673B1 (es)
JP (1) JP2008509976A (es)
KR (1) KR20070046175A (es)
CN (1) CN101023086A (es)
AR (1) AR050921A1 (es)
AT (1) ATE446301T1 (es)
AU (1) AU2005273704A1 (es)
BR (1) BRPI0514398A (es)
CA (1) CA2575056A1 (es)
DE (1) DE602005017283D1 (es)
IL (1) IL180811A0 (es)
MX (1) MX2007001954A (es)
NO (1) NO20070980L (es)
RU (1) RU2007109867A (es)
TW (1) TW200621260A (es)
UY (1) UY29074A1 (es)
WO (1) WO2006018627A1 (es)
ZA (1) ZA200701081B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2447077C2 (ru) 2004-08-18 2012-04-10 Астразенека Аб Энантиомеры выбранных конденсированных пиримидинов и их применение для лечения и предотвращения злокачественного новообразования
ATE474829T1 (de) * 2005-06-27 2010-08-15 Amgen Inc Entzündungshemmende arylnitrilverbindungen
CA2693062C (en) * 2007-06-21 2016-08-09 Neuronascent, Inc. Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration using isothiazolopyrimidinones
CN105963289B (zh) 2007-09-10 2021-02-26 北京强新生物科技有限公司 一类stat3通路抑制剂和癌干细胞通路抑制剂
EP2220061B1 (en) 2007-10-19 2016-02-17 Merck Sharp & Dohme Corp. Spiro-condensed 1, 3, 4-thiadiazole derivatives for inhibiting ksp kinesin activity
CN106211758B (zh) 2013-04-09 2021-03-23 北京强新生物科技有限公司 2-乙酰基萘并[2,3-b]呋喃-4,9-二酮用于治疗癌症的用途
US11299469B2 (en) 2016-11-29 2022-04-12 Sumitomo Dainippon Pharma Oncology, Inc. Naphthofuran derivatives, preparation, and methods of use thereof
JP2020520923A (ja) 2017-05-17 2020-07-16 ボストン バイオメディカル， インコーポレイテッド がんを処置するための方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60232994D1 (de) * 2001-12-06 2009-08-27 Merck & Co Inc Inhibitoren von mitotischem kinesin
WO2003049679A2 (en) * 2001-12-06 2003-06-19 Merck & Co., Inc. Mitotic kinesin inhibitors
NZ536190A (en) * 2002-04-17 2007-08-31 Cytokinetics Inc Compounds for treating cellular proliferative diseases by modulating the activity of the mitotic kinesin KSP
PT1601673E (pt) * 2003-03-07 2009-07-29 Astrazeneca Ab Heterociclos fundidos e suas utilizações
US7022850B2 (en) * 2003-05-22 2006-04-04 Bristol-Myers Squibb Co. Bicyclicpyrimidones and their use to treat diseases
US7345046B2 (en) * 2003-05-30 2008-03-18 Chiron Corporation Heteroaryl-fused pyrimidinyl compounds as anticancer agents

Also Published As

Publication number Publication date
TW200621260A (en) 2006-07-01
NO20070980L (no) 2007-03-12
WO2006018627A1 (en) 2006-02-23
CN101023086A (zh) 2007-08-22
CA2575056A1 (en) 2006-02-23
BRPI0514398A (pt) 2008-06-10
AU2005273704A1 (en) 2006-02-23
JP2008509976A (ja) 2008-04-03
EP1781673A1 (en) 2007-05-09
IL180811A0 (en) 2007-06-03
AR050921A1 (es) 2006-12-06
UY29074A1 (es) 2006-03-31
RU2007109867A (ru) 2008-09-27
US20070249636A1 (en) 2007-10-25
EP1781673B1 (en) 2009-10-21
DE602005017283D1 (de) 2009-12-03
ATE446301T1 (de) 2009-11-15
ZA200701081B (en) 2008-08-27
KR20070046175A (ko) 2007-05-02

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Legal Events

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