MD120C2 - Method of obtaining of macrocycle compounds - Google Patents
Method of obtaining of macrocycle compoundsInfo
- Publication number
- MD120C2 MD120C2 MD94-0092A MD940092A MD120C2 MD 120 C2 MD120 C2 MD 120C2 MD 940092 A MD940092 A MD 940092A MD 120 C2 MD120 C2 MD 120C2
- Authority
- MD
- Moldova
- Prior art keywords
- group
- formula
- alkyl
- obtaining
- action
- Prior art date
Links
- -1 macrocycle compounds Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 238000006467 substitution reaction Methods 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Abstract
The invention relates to the obtaining of macrocycle compounds with general formulawherein R1 represents methyl, ethyl or isoprophyl; R2 and R3 represent hydrogen atoms.OR4 represents hydroxy group, methoxy group, alkanoiloxy group, with a fragment C1-C6-alkyl without an indispensable substitution by phenoxy group, or-OCOOR5 group in which R5-C1-C5-alkyl, characterized by the fact that the compound with general formula II:wherein R1 and OR4 have the above indicated meanings, except of OR4 which represents hyperoxy group, 1-R11OCSO group,wherein R11 represents (C1-C6alkyl)-phenyl or phenyl is submissive to restoring through the action of tinhydroalkyl, for example, tri-n-hydrobutyltin in the presence of radical intiators, for example, azobisisobutyronitrile, or under the light action and chemical compound obtained with formula 1, wherein OR4 is a methoxy group or alkanoiloxy group with C1-C6-alkyl fragment, without an indispensable substitution, in case of necessary transforming in chemical compound with formula 1, wherein OR4 represents hydroxigroup which in case of necessity through the action of acid halide transforms in compound with formula 1, wherein OR4 is OCOOR5 group. New compounds according to the invention possess an antibiotic activity and/or are used as intermediar products at the obtaining of another active compounds.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858510944A GB8510944D0 (en) | 1985-04-30 | 1985-04-30 | Chemical compounds |
| SU4355074 RU2015981C1 (en) | 1985-04-30 | 1988-01-28 | Process for preparing macrocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD120B1 MD120B1 (en) | 1994-12-31 |
| MD120C2 true MD120C2 (en) | 1995-06-30 |
Family
ID=26289189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0092A MD120C2 (en) | 1985-04-30 | 1994-04-27 | Method of obtaining of macrocycle compounds |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD120C2 (en) |
-
1994
- 1994-04-27 MD MD94-0092A patent/MD120C2/en active IP Right Grant
Non-Patent Citations (3)
| Title |
|---|
| "Protective graups in Organic Chemistry by IFW. Me Omie Plenum Press London, 1973. * |
| Protective groups in Organic Synthesis by Theidora W. Oreene W.Key. Interscience, New York, 1981. * |
| ZA ą 85/7049, Int.cl5. C O7 D 493 /22, 1985. * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD120B1 (en) | 1994-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CS9101452A2 (en) | Method of phenylisoserine enantioselective derivatives preparation | |
| AU564842B2 (en) | Pyranyl (or cyclohexyl) methane sulfamates and their use as anticonvulsants | |
| CA2136622A1 (en) | Phosphotriester-type biologically active compounds | |
| BG37991A3 (en) | Method for stabilizing lyophylized preparation containing beta- lactamic antibiotic | |
| ATE13880T1 (en) | N-2-HYDROXYPROPYL-PIPERIDINES AND PROCESS FOR THEIR PREPARATION. | |
| MD120C2 (en) | Method of obtaining of macrocycle compounds | |
| AU5902690A (en) | Novel 3-methoximinopropionic esters and fungicides containing them | |
| EP0137155A3 (en) | Derivatives of alpha-alkyl polyolefinic compounds useful in the treatment of psoriasis | |
| ATE116991T1 (en) | SEMISYNTHETIC RHODOMYCINS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS CYTOSTATICS. | |
| GB2105724B (en) | Corticoid 17-ester 21-thioesters | |
| ATE20466T1 (en) | TRIAZOLYL KETONE OXIMES AND DIOXIMES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PLANT GROWTH REGULATORS. | |
| NL930069I1 (en) | Process for the preparation of 17-alpha-acyloxy-6-chloro-1-alpha, 2-alpha-methylene-4,6-pregnadiene-3,20-dione | |
| BR9106128A (en) | N-ACYL-AMINOalkyl-2-HYDROXYETHIL SULFETS AND A PROCESS FOR ITS PREPARATION | |
| SU972825A1 (en) | 1-(trialkylstannylthioalkyl)-silatranes exhibiting bacteristatic activity and method of their synthesis | |
| ATE17582T1 (en) | ANTIBIOTIC S/433, PROCESS FOR ITS PREPARATION AND ITS USE AS AN ANTITUMORS AGENT. | |
| YU49004B (en) | LANOST-7,9- DIEN-3ß, 32-DIOL AND THE PROCESS FOR IT'S PRODUCTION | |
| ES8302008A1 (en) | Cycloalkenylcarboxamido derivatives of tetramisole, their preparation and use in medicine. | |
| TH2142B (en) | 1H-Imidazole replaced. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20080127 |