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MA63911B1 - Méthode de détermination de la concentration d'un analyte dans un échantillon de fluide corporel, dispositif mobile, trousse, programme informatique et support de stockage lisible par ordinateur - Google Patents

Méthode de détermination de la concentration d'un analyte dans un échantillon de fluide corporel, dispositif mobile, trousse, programme informatique et support de stockage lisible par ordinateur

Info

Publication number
MA63911B1
MA63911B1 MA63911A MA63911A MA63911B1 MA 63911 B1 MA63911 B1 MA 63911B1 MA 63911 A MA63911 A MA 63911A MA 63911 A MA63911 A MA 63911A MA 63911 B1 MA63911 B1 MA 63911B1
Authority
MA
Morocco
Prior art keywords
test field
intensity
reference fields
image
color
Prior art date
Application number
MA63911A
Other languages
English (en)
Inventor
Bernd Limburg
Max Berg
Fredrik HAILER
Volker Tuerck
Momme Winkelnkemper
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of MA63911B1 publication Critical patent/MA63911B1/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N1/00—Scanning, transmission or reproduction of documents or the like, e.g. facsimile transmission; Details thereof
    • H04N1/46—Colour picture communication systems
    • H04N1/56—Processing of colour picture signals
    • H04N1/60—Colour correction or control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/29—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using visual detection
    • G01N21/293—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using visual detection with colour charts, graduated scales or turrets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/90—Dynamic range modification of images or parts thereof
    • G06T5/92—Dynamic range modification of images or parts thereof based on global image properties
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/40—Extraction of image or video features
    • G06V10/60—Extraction of image or video features relating to illumination properties, e.g. using a reflectance or lighting model
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N9/00—Details of colour television systems
    • H04N9/64—Circuits for processing colour signals
    • H04N9/73—Colour balance circuits, e.g. white balance circuits or colour temperature control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1765—Method using an image detector and processing of image signal
    • G01N2021/177—Detector of the video camera type
    • G01N2021/1776—Colour camera
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7756—Sensor type
    • G01N2021/7759—Dipstick; Test strip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band
    • G01N2021/8488—Investigating reagent band the band presenting reference patches
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/022—Casings
    • G01N2201/0221—Portable; cableless; compact; hand-held
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10024—Color image

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Multimedia (AREA)
  • Molecular Biology (AREA)
  • Signal Processing (AREA)
  • Mathematical Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Software Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

L'invention concerne un procédé de détermination de la concentration d'au moins un analyte dans un échantillon d'un fluide corporel à l'aide d'un dispositif mobile (112) comportant au moins un appareil photo (120), le procédé comprenant : i) la capture, à l'aide de l'appareil photo (120), d'au moins une image d'au moins une partie d'une carte de référence de couleur (118) et d'au moins une partie d'au moins un champ de test (116) de réactif d'au moins une bande d'essai optique (114) sur laquelle est appliqué l'échantillon, le champ de test (116) se trouvant, dans l'image, dans une position définie par rapport à la carte de référence de couleur (118), la carte de référence de couleurs (118) comprenant une pluralité de champs de référence gris (126) différents affectés localement au champ de test (116), la pluralité de champs de référence gris (126) et le champ de test (116) étant affectés localement l'un à l'autre en étant disposés dans des positions voisines ou la pluralité de champs de référence gris (126) affectés localement au champ de test (116) étant disposés sur la carte de référence de couleurs (118) de telle sorte que la pluralité de champs de référence gris (126) entoure le champ de test (116) ; ii) l'application d'au moins une correction prédéterminée de carte de tons moyens basée sur les pixels à l'image obtenue à l'étape i), permettant ainsi d'obtenir au moins une première image corrigée en intensité, la correction prédéterminée de carte de tons moyens basée sur les pixels comprenant une affectation d'une seconde valeur de luminosité à une première valeur de luminosité, la première valeur de luminosité étant enregistrée par l'appareil photo (120), chaque pixel de l'image enregistrée étant corrigé individuellement par la correction de carte de tons moyens basée sur les pixels prédéterminée, la correction de carte de tons moyens étant dérivée en combinant une pluralité de corrections de carte de tons pour différents types de dispositifs mobiles ; iii) la dérivation, à partir de la première image corrigée en intensité, d'informations de luminosité locale (174) pour au moins certains des champs de référence de couleur (128) et pour le champ de test (116), en utilisant les champs de référence de gris (126) affectés localement aux champs de référence de couleur (128) et au champ de test (116), respectivement, les informations de luminosité locale (174) comprenant une indication numérique décrivant l'intensité locale d'au moins une couleur RVB des champs de référence de couleur (128) et du champ de test (116), respectivement ; iv) l'application d'au moins une correction de carte de tons propre au dispositif mobile à la première image corrigée en intensité, la correction de carte de tons propre au dispositif mobile prenant en compte les informations de luminosité locale (174), obtenant ainsi au moins une seconde image corrigée en intensité ; et v) la détermination de la concentration d'analyte sur la base d'une réaction de formation de couleur du champ de test (116) en utilisant la seconde image corrigée en intensité.
MA63911A 2020-06-09 2021-06-07 Méthode de détermination de la concentration d'un analyte dans un échantillon de fluide corporel, dispositif mobile, trousse, programme informatique et support de stockage lisible par ordinateur MA63911B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP20179002 2020-06-09
EP20188732 2020-07-30
EP21731124.0A EP4162259B1 (fr) 2020-06-09 2021-06-07 Méthode de détermination de la concentration d'un analyte dans un échantillon de fluide corporel, dispositif mobile, trousse, programme informatique et support de stockage lisible par ordinateur
PCT/EP2021/065087 WO2021249895A1 (fr) 2020-06-09 2021-06-07 Méthode de détermination de la concentration d'un analyte dans un échantillon de fluide corporel, dispositif mobile, trousse, programme informatique et support de stockage lisible par ordinateur

Publications (1)

Publication Number Publication Date
MA63911B1 true MA63911B1 (fr) 2024-12-31

Family

ID=76355499

Family Applications (1)

Application Number Title Priority Date Filing Date
MA63911A MA63911B1 (fr) 2020-06-09 2021-06-07 Méthode de détermination de la concentration d'un analyte dans un échantillon de fluide corporel, dispositif mobile, trousse, programme informatique et support de stockage lisible par ordinateur

Country Status (10)

Country Link
EP (1) EP4162259B1 (fr)
JP (1) JP2023528942A (fr)
KR (1) KR20230020993A (fr)
CN (1) CN115667893A (fr)
BR (1) BR112022025130A2 (fr)
CA (1) CA3179621A1 (fr)
ES (1) ES2998484T3 (fr)
MA (1) MA63911B1 (fr)
PL (1) PL4162259T3 (fr)
WO (1) WO2021249895A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240148345A (ko) * 2022-02-11 2024-10-11 에프. 호프만-라 로슈 아게 분석 측정을 수행하기 위한 방법 및 장치
CN114782444B (zh) * 2022-06-22 2022-09-02 江苏美克医学技术有限公司 用于体外诊断显色结果的辅助判读方法、介质和电子设备
JP7775155B2 (ja) * 2022-07-12 2025-11-25 株式会社日立ソリューションズ 二次元コードの読取システム及び二次元コード
CN116740478B (zh) * 2023-06-16 2025-12-26 中南大学 一种基于图像识别的浓密机料浆浓度测量系统
CN119090871B (zh) * 2024-11-05 2025-01-21 西安医学院第二附属医院 一种检验科用尿液标本智能检测方法及系统

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Publication number Priority date Publication date Assignee Title
GB201000835D0 (en) 2010-01-19 2010-03-03 Akzo Nobel Coatings Int Bv Method and system for determining colour from an image
GB201105474D0 (en) 2011-03-31 2011-05-18 Albagaia Ltd Testing apparatus
WO2015038717A1 (fr) * 2013-09-11 2015-03-19 Wellumina Health, Inc. Système pour le test diagnostique d'échantillons liquides
US10469807B2 (en) 2013-09-11 2019-11-05 Color Match, LLC Color measurement and calibration
US10991096B2 (en) 2014-05-12 2021-04-27 Healthy.Io Ltd. Utilizing personal communications devices for medical testing
DE102017204463A1 (de) * 2017-03-17 2018-09-20 Sirona Dental Systems Gmbh Farbreferenz zur Kalibrierung einer dentalen Farbkamera
HUE058133T2 (hu) * 2018-11-07 2022-07-28 Hoffmann La Roche Eljárások és eszközök analitikai mérés elvégzéséhez
KR102605420B1 (ko) * 2018-11-30 2023-11-22 에프. 호프만-라 로슈 아게 체액 내의 분석물의 농도를 측정하는 방법

Also Published As

Publication number Publication date
EP4162259A1 (fr) 2023-04-12
JP2023528942A (ja) 2023-07-06
PL4162259T3 (pl) 2025-02-10
EP4162259C0 (fr) 2024-10-16
BR112022025130A2 (pt) 2022-12-27
WO2021249895A1 (fr) 2021-12-16
TW202215033A (zh) 2022-04-16
CA3179621A1 (fr) 2021-12-16
EP4162259B1 (fr) 2024-10-16
KR20230020993A (ko) 2023-02-13
ES2998484T3 (en) 2025-02-20
CN115667893A (zh) 2023-01-31
US20230103160A1 (en) 2023-03-30

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