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MA46366B1 - Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique contre l'il-23 - Google Patents

Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique contre l'il-23

Info

Publication number
MA46366B1
MA46366B1 MA46366A MA46366A MA46366B1 MA 46366 B1 MA46366 B1 MA 46366B1 MA 46366 A MA46366 A MA 46366A MA 46366 A MA46366 A MA 46366A MA 46366 B1 MA46366 B1 MA 46366B1
Authority
MA
Morocco
Prior art keywords
safe
specific antibody
treating psoriasis
effective method
patient
Prior art date
Application number
MA46366A
Other languages
English (en)
Other versions
MA46366A (fr
Inventor
Bruce Randazzo
Yasmine WASFI
Original Assignee
Janssen Biotech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech, Inc. filed Critical Janssen Biotech, Inc.
Publication of MA46366A publication Critical patent/MA46366A/fr
Publication of MA46366B1 publication Critical patent/MA46366B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention porte sur une méthode de traitement du psoriasis chez un patient par l'administration d'un anticorps spécifique contre l'IL-23, par exemple, le guselkumab, dans une quantité sûre et efficace, pour que le patient atteigne un PASI90, PASI100 ou IGA de 0 ou 1 tel que mesuré 16, 24, 32, 40 et 48 semaines après un traitement initial.
MA46366A 2016-09-30 2017-09-29 Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique contre l'il-23 MA46366B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662402403P 2016-09-30 2016-09-30
US201762532068P 2017-07-13 2017-07-13
PCT/US2017/054217 WO2018064436A1 (fr) 2016-09-30 2017-09-29 Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique contre l'il-23
EP17857471.1A EP3519049B1 (fr) 2016-09-30 2017-09-29 Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique contre l'il-23

Publications (2)

Publication Number Publication Date
MA46366A MA46366A (fr) 2019-08-07
MA46366B1 true MA46366B1 (fr) 2025-12-31

Family

ID=61757820

Family Applications (1)

Application Number Title Priority Date Filing Date
MA46366A MA46366B1 (fr) 2016-09-30 2017-09-29 Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique contre l'il-23

Country Status (14)

Country Link
US (3) US20180094052A1 (fr)
EP (1) EP3519049B1 (fr)
JP (3) JP2020500152A (fr)
KR (2) KR20240046648A (fr)
AU (2) AU2017336799B2 (fr)
CA (1) CA3037961A1 (fr)
FI (1) FI3519049T3 (fr)
IL (3) IL316408A (fr)
LT (1) LT3519049T (fr)
MA (1) MA46366B1 (fr)
MX (1) MX2019003703A (fr)
PT (1) PT3519049T (fr)
SM (1) SMT202500497T1 (fr)
WO (1) WO2018064436A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200076731A (ko) 2017-11-06 2020-06-29 얀센 바이오테크 인코포레이티드 항-il23 특이적 항체로 건선성 관절염을 치료하는 안전하고 유효한 방법
EP3762015B1 (fr) 2018-03-05 2025-12-24 Janssen Biotech, Inc. Guselkumab pour l'utilisation dans le traitement de la maladie de crohn avec un plan de dosage
US20190345245A1 (en) * 2018-05-11 2019-11-14 Janssen Biotech, Inc. Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody
US20200025776A1 (en) * 2018-07-18 2020-01-23 Janssen Biotech, Inc. Sustained Response Predictors After Treatment With Anti-IL23 Specific Antibody
EP3883607A4 (fr) * 2018-11-20 2022-08-17 Janssen Biotech, Inc. Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique anti-il-23
CN115697410A (zh) * 2020-04-20 2023-02-03 艾德沙生物科技研究公司 用于治疗急性呼吸窘迫综合征的组合物和方法
US20210347880A1 (en) * 2020-05-05 2021-11-11 Janssen Biotech, Inc. Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody
MX2022014430A (es) 2020-05-21 2023-02-22 Janssen Biotech Inc Método para tratar la enfermedad inflamatoria del intestino con una terapia de combinación de anticuerpos para il-23 y tnf alfa.
US20220025035A1 (en) * 2020-07-13 2022-01-27 Janssen Biotech, Inc. Safe and Effective Method of Treating Psoriatic Arthritis with Anti-IL23 Specific Antibody
CN117751138A (zh) * 2021-03-12 2024-03-22 詹森生物科技公司 用抗il23特异性抗体治疗银屑病关节炎的安全且有效的方法
US20220372129A1 (en) 2021-05-20 2022-11-24 Janssen Biotech, Inc. Method of Treating Inflammatory Bowel Disease with a Combination Therapy of Antibodies to IL-23 and TNF Alpha
AU2022414309A1 (en) * 2021-12-17 2024-08-01 Janssen Biotech, Inc. Il-23 specific antibodies for the treatment of systemic sclerosis
WO2024228134A1 (fr) 2023-05-03 2024-11-07 Janssen Biotech, Inc. Procédé de traitement de la colite ulcéreuse avec une combinaison d'anticorps contre il-23 et tnf alpha
TW202508626A (zh) 2023-05-03 2025-03-01 美商健生生物科技公司 以針對ＩＬ－２３及ＴＮＦα的抗體的組合來治療克隆氏症之方法

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