MA38212A1 - New compounds - Google Patents
New compoundsInfo
- Publication number
- MA38212A1 MA38212A1 MA38212A MA38212A MA38212A1 MA 38212 A1 MA38212 A1 MA 38212A1 MA 38212 A MA38212 A MA 38212A MA 38212 A MA38212 A MA 38212A MA 38212 A1 MA38212 A1 MA 38212A1
- Authority
- MA
- Morocco
- Prior art keywords
- compounds
- integer
- value
- useful
- treatment
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 102000014150 Interferons Human genes 0.000 abstract 2
- 108010050904 Interferons Proteins 0.000 abstract 2
- 229940079322 interferon Drugs 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 201000009961 allergic asthma Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012646 vaccine adjuvant Substances 0.000 abstract 1
- 229940124931 vaccine adjuvant Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne des composés de formule (i) et des sels de ceux-ci, parmi lesquels r1 est n-alkyle en c4-6 ou alcoxy en c1-2alkyle en c1-2; r2 est hydrogène ou méthyle; chaque r3 est hydroxy, halo ou n-alkyle en c1-3, et m est un nombre entier ayant une valeur de 2 à 4; n est un nombre entier ayant une valeur de 0 à 3; p est un nombre entier ayant une valeur de 0 à 2. Ces composés sont des inducteurs d'interféron humain. Les composés qui induisent l'interféron humain peuvent être utiles dans le traitement de divers troubles, par exemple dans le traitement de maladies allergiques et d'autres états inflammatoires, comme la rhinite allergique et l'asthme, de maladies infectieuses et du cancer, et peuvent également être utiles comme adjuvants de vaccins.The invention relates to compounds of formula (i) and salts thereof, of which r1 is n-C4-6alkyl or C1-2alkoxyC1-2alkyl; R2 is hydrogen or methyl; each r 3 is hydroxy, halo or n-C 1-3 alkyl, and m is an integer having a value of 2 to 4; n is an integer having a value of 0 to 3; p is an integer having a value of 0 to 2. These compounds are inducers of human interferon. Compounds that induce human interferon may be useful in the treatment of various disorders, for example in the treatment of allergic diseases and other inflammatory conditions, such as allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261728390P | 2012-11-20 | 2012-11-20 | |
| PCT/US2013/070472 WO2014081645A1 (en) | 2012-11-20 | 2013-11-18 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA38212A1 true MA38212A1 (en) | 2017-06-30 |
Family
ID=59745504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA38212A MA38212A1 (en) | 2012-11-20 | 2013-11-18 | New compounds |
Country Status (1)
| Country | Link |
|---|---|
| MA (1) | MA38212A1 (en) |
-
2013
- 2013-11-18 MA MA38212A patent/MA38212A1/en unknown
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