MA35085B1 - Procede de traitement d'une nephropathie induite par les produits de contraste - Google Patents
Procede de traitement d'une nephropathie induite par les produits de contrasteInfo
- Publication number
- MA35085B1 MA35085B1 MA35961A MA35961A MA35085B1 MA 35085 B1 MA35085 B1 MA 35085B1 MA 35961 A MA35961 A MA 35961A MA 35961 A MA35961 A MA 35961A MA 35085 B1 MA35085 B1 MA 35085B1
- Authority
- MA
- Morocco
- Prior art keywords
- contrast agents
- treating nephropathy
- nephropathy induced
- present
- induced
- Prior art date
Links
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A61K31/19—Carboxylic acids, e.g. valproic acid
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- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
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Abstract
La présente invention concerne l'utilisation d'un inhibiteur de l'endopeptidase neutre, dans la fabrication d'un médicament destiné au traitement, à l'amélioration et/ou à la prévention d'une néphropathie induite par les produits de contraste. La présente invention concerne en outre l'utilisation d'un composé de formule (i) dans laquelle r
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41417410P | 2010-11-16 | 2010-11-16 | |
| PCT/EP2011/070084 WO2012065958A1 (fr) | 2010-11-16 | 2011-11-14 | Procédé de traitement d'une néphropathie induite par les produits de contraste |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA35085B1 true MA35085B1 (fr) | 2014-05-02 |
Family
ID=44993552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA35961A MA35085B1 (fr) | 2010-11-16 | 2013-06-05 | Procede de traitement d'une nephropathie induite par les produits de contraste |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US8993631B2 (fr) |
| EP (1) | EP2640375B1 (fr) |
| JP (1) | JP5950926B2 (fr) |
| KR (1) | KR101886894B1 (fr) |
| CN (2) | CN104306974B (fr) |
| AU (1) | AU2011331296C1 (fr) |
| BR (1) | BR112013011876A2 (fr) |
| CA (1) | CA2817784C (fr) |
| CL (1) | CL2013001383A1 (fr) |
| EA (1) | EA029672B1 (fr) |
| ES (1) | ES2587447T3 (fr) |
| IL (1) | IL226351A (fr) |
| MA (1) | MA35085B1 (fr) |
| MX (1) | MX2013005543A (fr) |
| PH (1) | PH12013500993A1 (fr) |
| PL (1) | PL2640375T3 (fr) |
| PT (1) | PT2640375T (fr) |
| SG (1) | SG190229A1 (fr) |
| TW (1) | TWI576331B (fr) |
| WO (1) | WO2012065958A1 (fr) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG191175A1 (en) | 2010-12-15 | 2013-07-31 | Theravance Inc | Neprilysin inhibitors |
| WO2012082853A1 (fr) | 2010-12-15 | 2012-06-21 | Theravance, Inc. | Inhibiteurs de néprilysine |
| US8449890B2 (en) | 2011-02-17 | 2013-05-28 | Theravance, Inc. | Neprilysin inhibitors |
| CN103380119B (zh) | 2011-02-17 | 2016-02-17 | 施万生物制药研发Ip有限责任公司 | 作为脑啡肽酶抑制剂的经取代的氨基丁酸衍生物 |
| CN103582630B (zh) | 2011-05-31 | 2016-08-17 | 施万生物制药研发Ip有限责任公司 | 脑啡肽酶抑制剂 |
| CA2835216A1 (fr) | 2011-05-31 | 2012-12-06 | Theravance, Inc. | Inhibiteurs de neprilysine |
| WO2012166389A1 (fr) | 2011-05-31 | 2012-12-06 | Theravance, Inc. | Inhibiteurs de néprilysine |
| TWI560172B (en) | 2011-11-02 | 2016-12-01 | Theravance Biopharma R&D Ip Llc | Neprilysin inhibitors |
| CN104350052B (zh) * | 2012-05-31 | 2017-05-31 | 施万生物制药研发Ip有限责任公司 | 一氧化氮供体脑啡肽酶抑制剂 |
| EP2858650B1 (fr) | 2012-06-08 | 2018-11-14 | Theravance Biopharma R&D IP, LLC | Inhibiteurs de la néprilysine |
| KR102102197B1 (ko) * | 2012-06-08 | 2020-04-20 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | 네프릴리신 억제제 |
| EP2882716B9 (fr) | 2012-08-08 | 2018-12-26 | Theravance Biopharma R&D IP, LLC | Inhibiteurs de la neprilysin |
| JP6295277B2 (ja) * | 2013-02-14 | 2018-03-14 | ノバルティス アーゲー | Nep(中性エンドペプチダーゼ)阻害剤としての置換ビスフェニルブタン酸ホスホン酸誘導体 |
| AU2014216417B2 (en) * | 2013-02-14 | 2016-05-12 | Novartis Ag | Substituted bisphenyl butanoic acid derivatives as NEP inhibitors with improved in vivo efficacy |
| RS56300B1 (sr) * | 2013-03-05 | 2017-12-29 | Theravance Biopharma R&D Ip Llc | Inhibitori neprilizina |
| KR20160113291A (ko) | 2014-01-30 | 2016-09-28 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | 네프리리신 저해제 |
| US9585882B2 (en) | 2014-01-30 | 2017-03-07 | Theravance Biopharma R&D Ip, Llc | Neprilysin inhibitors |
| WO2016037098A1 (fr) * | 2014-09-04 | 2016-03-10 | Concert Pharmaceuticals, Inc. | Sacubitril deutérisé |
| CN104557600B (zh) * | 2015-01-26 | 2016-05-04 | 苏州明锐医药科技有限公司 | 沙库比曲的制备方法 |
| BR112017017317B1 (pt) | 2015-02-11 | 2023-02-14 | Theravance Biopharma R&D Ip, Llc | Composto, forma cristalina, composições farmacêuticas, forma de dosagem oral ou intravenosa, processos para a preparação do composto ou da forma cristalina e uso |
| KR102573351B1 (ko) | 2015-02-19 | 2023-09-01 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | (2r, 4r)-5-(5'-클로로-2'-플루오로비페닐-4-일)-2-히드록시-4-[(5-메틸옥사졸-2-카르보닐)아미노]펜타노익산 |
| CA2980224C (fr) * | 2015-03-20 | 2019-06-25 | Crystal Pharmatech Co., Ltd. | Forme cristalline de ahu377, procede de preparation et utilisation de cette derniere |
| CN105061263B (zh) * | 2015-08-11 | 2017-03-15 | 苏州楚凯药业有限公司 | 一种nep抑制剂中间体的制备方法 |
| CN105523964B (zh) * | 2015-12-09 | 2017-05-24 | 苏州楚凯药业有限公司 | 一种抗心衰药物中间体的制备方法 |
| JP7306828B2 (ja) | 2016-03-08 | 2023-07-11 | セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー | 結晶性(2s,4r)-5-(5’-クロロ-2’-フルオロ-[1,1’-ビフェニル]-4-イル)-2-(エトキシメチル)-4-(3-ヒドロキシイソオキサゾール-5-カルボキサミド)-2-メチルペンタン酸およびその使用 |
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| CN105963569A (zh) * | 2016-06-25 | 2016-09-28 | 许风英 | 一种预防缓解碘造影剂副作用的中药制剂 |
| CN107602399B (zh) * | 2016-07-11 | 2020-09-25 | 江西东邦药业有限公司 | 一种脑啡肽酶抑制剂中间体的制备方法 |
| CN107382785B (zh) * | 2017-08-09 | 2019-11-01 | 常州制药厂有限公司 | 一种沙库必曲关键中间体的制备方法 |
| FR3072379B1 (fr) * | 2017-10-18 | 2020-08-07 | Pharmasynthese | Nouveaux derives de la strombine et leur utilisation en cosmetique |
| UY38072A (es) | 2018-02-07 | 2019-10-01 | Novartis Ag | Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos |
| WO2020254553A1 (fr) | 2019-06-19 | 2020-12-24 | Nmd Pharma A/S | Composés destinés au traitement de troubles neuromusculaires |
| CN110711544A (zh) * | 2019-10-12 | 2020-01-21 | 浙江理工大学上虞工业技术研究院有限公司 | 一种自粘性芳香微胶囊的制备方法 |
| EP4134079A4 (fr) | 2020-04-08 | 2024-04-24 | Aptabio Therapeutics Inc. | Agent pour le traitement d'une lésion rénale aiguë induite par produit de contraste |
| KR102308991B1 (ko) | 2020-04-08 | 2021-10-06 | 압타바이오 주식회사 | 조영제 유발 급성 신부전 치료제 |
| KR102504090B1 (ko) | 2020-08-05 | 2023-02-24 | 경상국립대학교병원 | 조영제-유발 신독성 예방 또는 치료용 약학 조성물 |
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-
2011
- 2011-11-11 US US13/294,295 patent/US8993631B2/en not_active Expired - Fee Related
- 2011-11-14 KR KR1020137015363A patent/KR101886894B1/ko not_active Expired - Fee Related
- 2011-11-14 CN CN201410468788.9A patent/CN104306974B/zh not_active Expired - Fee Related
- 2011-11-14 SG SG2013035886A patent/SG190229A1/en unknown
- 2011-11-14 PT PT117846386T patent/PT2640375T/pt unknown
- 2011-11-14 PL PL11784638T patent/PL2640375T3/pl unknown
- 2011-11-14 AU AU2011331296A patent/AU2011331296C1/en not_active Ceased
- 2011-11-14 CA CA2817784A patent/CA2817784C/fr not_active Expired - Fee Related
- 2011-11-14 EA EA201390707A patent/EA029672B1/ru not_active IP Right Cessation
- 2011-11-14 JP JP2013539220A patent/JP5950926B2/ja not_active Expired - Fee Related
- 2011-11-14 PH PH1/2013/500993A patent/PH12013500993A1/en unknown
- 2011-11-14 BR BR112013011876A patent/BR112013011876A2/pt not_active Application Discontinuation
- 2011-11-14 EP EP11784638.6A patent/EP2640375B1/fr not_active Not-in-force
- 2011-11-14 WO PCT/EP2011/070084 patent/WO2012065958A1/fr not_active Ceased
- 2011-11-14 MX MX2013005543A patent/MX2013005543A/es not_active Application Discontinuation
- 2011-11-14 CN CN201180065284.7A patent/CN103313708B/zh not_active Expired - Fee Related
- 2011-11-14 ES ES11784638.6T patent/ES2587447T3/es active Active
- 2011-11-15 TW TW100141713A patent/TWI576331B/zh not_active IP Right Cessation
-
2013
- 2013-05-13 IL IL226351A patent/IL226351A/en active IP Right Grant
- 2013-05-15 CL CL2013001383A patent/CL2013001383A1/es unknown
- 2013-06-05 MA MA35961A patent/MA35085B1/fr unknown
-
2014
- 2014-07-28 US US14/341,977 patent/US20140336194A1/en not_active Abandoned
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