MA35882B1 - Pde9 inhibitors comprising an imidazotriazinone skeleton - Google Patents
Pde9 inhibitors comprising an imidazotriazinone skeletonInfo
- Publication number
- MA35882B1 MA35882B1 MA37237A MA37237A MA35882B1 MA 35882 B1 MA35882 B1 MA 35882B1 MA 37237 A MA37237 A MA 37237A MA 37237 A MA37237 A MA 37237A MA 35882 B1 MA35882 B1 MA 35882B1
- Authority
- MA
- Morocco
- Prior art keywords
- compound
- formula
- present
- relates
- effective amount
- Prior art date
Links
- 229940076380 PDE9 inhibitor Drugs 0.000 title 1
- IJYHVZICHKCLMQ-UHFFFAOYSA-N imidazo[4,5-d]triazin-4-one Chemical group O=C1N=NN=C2N=CN=C12 IJYHVZICHKCLMQ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
La présente invention concerne des composés qui sont des inhibiteurs de l'enzyme pde9. L'invention concerne une composition pharmaceutique qui comprend une quantité thérapeutiquement efficace d'un composé de l'invention et un excipient pharmaceutiquement acceptable. La présente invention concerne également des procédés de préparation des composés de formule (i). La présente invention concerne en outre une méthode de traitement d'un sujet souffrant d'une maladie neurodégénérative, qui comprend l'administration au sujet d'une quantité thérapeutiquement efficace d'un composé de formule (i). La présente invention concerne en outre un composé de formule (i) pour une utilisation dans une méthode de traitement d'un sujet souffrant d'un trouble psychiatrique, comprenant l'administration au sujet d'une quantité thérapeutiquement efficace d'un composé de formule (i).The present invention relates to compounds which are inhibitors of the enzyme pde9. The invention relates to a pharmaceutical composition which comprises a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable excipient. The present invention also relates to processes for preparing compounds of formula (i). The present invention further relates to a method of treating a subject suffering from a neurodegenerative disease, which comprises administering to a subject a therapeutically effective amount of a compound of formula (i). The present invention further relates to a compound of formula (i) for use in a method of treating a subject suffering from a psychiatric disorder, comprising administering to a therapeutically effective amount a compound of formula (i).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012070718 | 2012-01-26 | ||
| PCT/EP2013/051451 WO2013110768A1 (en) | 2012-01-26 | 2013-01-25 | Pde9 inhibitors with imidazo triazinone backbone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA35882B1 true MA35882B1 (en) | 2014-12-01 |
Family
ID=53171642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA37237A MA35882B1 (en) | 2012-01-26 | 2014-07-23 | Pde9 inhibitors comprising an imidazotriazinone skeleton |
Country Status (1)
| Country | Link |
|---|---|
| MA (1) | MA35882B1 (en) |
-
2014
- 2014-07-23 MA MA37237A patent/MA35882B1/en unknown
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