MA35878B1 - Utilisation thérapeutique de dérivés d'imidazopyridine - Google Patents
Utilisation thérapeutique de dérivés d'imidazopyridineInfo
- Publication number
- MA35878B1 MA35878B1 MA37231A MA37231A MA35878B1 MA 35878 B1 MA35878 B1 MA 35878B1 MA 37231 A MA37231 A MA 37231A MA 37231 A MA37231 A MA 37231A MA 35878 B1 MA35878 B1 MA 35878B1
- Authority
- MA
- Morocco
- Prior art keywords
- therapeutic use
- imidazopyridine derivatives
- phenyl ring
- medicament
- formulas
- Prior art date
Links
- 125000004857 imidazopyridinyl group Chemical class N1C(=NC2=C1C=CC=N2)* 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 206010005003 Bladder cancer Diseases 0.000 abstract 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000005112 urinary bladder cancer Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
L'invention concerne l'utilisation de composés représentés par la formule (i) dans laquelle r2 et r3 forment ensemble avec les atomes de carbone du noyau phényle auquel ils sont liés un hétérocycle azoté à 6 chaînons correspondant à l'une des formules (a), (b) et (c) dans laquelle les lignes ondulées représentent le noyau phényle auquel r2 et r3 sont liés, ou d'un sel de ceux-ci pharmaceutiquement acceptable, pour préparer un médicament afin de traiter le cancer de la vessie.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1250075A FR2985185B1 (fr) | 2012-01-04 | 2012-01-04 | Utilisation en therapeutique de derives d'imidazopyridine |
| PCT/IB2013/050048 WO2013102860A1 (fr) | 2012-01-04 | 2013-01-03 | Utilisation thérapeutique de dérivés d'imidazopyridine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA35878B1 true MA35878B1 (fr) | 2014-12-01 |
Family
ID=47630451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA37231A MA35878B1 (fr) | 2012-01-04 | 2014-07-23 | Utilisation thérapeutique de dérivés d'imidazopyridine |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US9732078B2 (fr) |
| EP (1) | EP2800566B1 (fr) |
| JP (1) | JP6067032B2 (fr) |
| KR (1) | KR102046196B1 (fr) |
| CN (1) | CN104144687B (fr) |
| AU (1) | AU2013207082B2 (fr) |
| BR (1) | BR112014016632A8 (fr) |
| CA (1) | CA2860413C (fr) |
| CL (1) | CL2014001784A1 (fr) |
| CO (1) | CO7020916A2 (fr) |
| EA (1) | EA027058B1 (fr) |
| ES (1) | ES2560619T3 (fr) |
| FR (1) | FR2985185B1 (fr) |
| HK (1) | HK1198690A1 (fr) |
| IL (1) | IL233493A (fr) |
| MA (1) | MA35878B1 (fr) |
| MX (1) | MX336340B (fr) |
| PH (1) | PH12014501537A1 (fr) |
| PL (1) | PL2800566T3 (fr) |
| SG (1) | SG11201403793UA (fr) |
| TW (1) | TWI557122B (fr) |
| UY (1) | UY34564A (fr) |
| WO (1) | WO2013102860A1 (fr) |
| ZA (1) | ZA201404928B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2994141A4 (fr) * | 2013-05-10 | 2016-11-23 | Nimbus Apollo Inc | Inhibiteurs de l'acc et utilisations associées |
| KR102627756B1 (ko) * | 2017-03-22 | 2024-01-23 | 쑤저우 바이지부공 파마수티컬 테크널러지 컴퍼니 리미티드 | 브루톤 타이로신 키나제 억제제 |
| CN115490687B (zh) * | 2022-09-19 | 2023-10-27 | 国家烟草质量监督检验中心 | 3-苯并呋喃基硫咪唑并吡啶衍生物及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2859997B1 (fr) | 2003-09-18 | 2006-02-03 | Sanofi Synthelabo | Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant. |
| FR2883286B1 (fr) * | 2005-03-16 | 2008-10-03 | Sanofi Aventis Sa | NOUVEAUX DERIVES D'IMIDAZO[1,5-a]PYRIDINES, INHIBITEURS DE FGFs, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT |
| FR2896247B1 (fr) * | 2006-01-13 | 2008-02-29 | Sanofi Aventis Sa | Composes dimeres agonistes des recepteurs des fgfs (fgfrs), leur procede de preparation et leur application en therapeutique |
| EP1891955A1 (fr) | 2006-07-24 | 2008-02-27 | Sanofi-Aventis | Utilisation de dérivés de indolizines, inhibiteurs de FGF, pour la préparation d'un médicament pour le traitement d'affections dégénératives des articulations |
| CN1887878A (zh) | 2006-07-26 | 2007-01-03 | 浙江大学 | 三嗪氮氧化物及合成方法和用途 |
| FR2962437B1 (fr) * | 2010-07-06 | 2012-08-17 | Sanofi Aventis | Derives d'imidazopyridine, leur procede de preparation et leur application en therapeutique |
-
2012
- 2012-01-04 FR FR1250075A patent/FR2985185B1/fr not_active Expired - Fee Related
-
2013
- 2013-01-03 AU AU2013207082A patent/AU2013207082B2/en active Active
- 2013-01-03 SG SG11201403793UA patent/SG11201403793UA/en unknown
- 2013-01-03 KR KR1020147021454A patent/KR102046196B1/ko active Active
- 2013-01-03 EP EP13702101.0A patent/EP2800566B1/fr active Active
- 2013-01-03 PL PL13702101T patent/PL2800566T3/pl unknown
- 2013-01-03 EA EA201491307A patent/EA027058B1/ru not_active IP Right Cessation
- 2013-01-03 JP JP2014550790A patent/JP6067032B2/ja active Active
- 2013-01-03 US US14/370,462 patent/US9732078B2/en active Active
- 2013-01-03 MX MX2014008244A patent/MX336340B/es unknown
- 2013-01-03 BR BR112014016632A patent/BR112014016632A8/pt not_active Application Discontinuation
- 2013-01-03 CN CN201380012217.8A patent/CN104144687B/zh active Active
- 2013-01-03 HK HK14112128.4A patent/HK1198690A1/xx unknown
- 2013-01-03 ES ES13702101.0T patent/ES2560619T3/es active Active
- 2013-01-03 CA CA2860413A patent/CA2860413C/fr active Active
- 2013-01-03 WO PCT/IB2013/050048 patent/WO2013102860A1/fr not_active Ceased
- 2013-01-04 UY UY0001034564A patent/UY34564A/es not_active Application Discontinuation
- 2013-01-04 TW TW102100344A patent/TWI557122B/zh active
-
2014
- 2014-07-02 IL IL233493A patent/IL233493A/en active IP Right Grant
- 2014-07-03 CL CL2014001784A patent/CL2014001784A1/es unknown
- 2014-07-03 PH PH12014501537A patent/PH12014501537A1/en unknown
- 2014-07-04 ZA ZA2014/04928A patent/ZA201404928B/en unknown
- 2014-07-23 MA MA37231A patent/MA35878B1/fr unknown
- 2014-07-28 CO CO14163266A patent/CO7020916A2/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA34450B1 (fr) | Dérivés de l'imidazopyridine, procédé pour leur préparation, et leur utilisation thérapeutique | |
| MA38323B1 (fr) | Dérivés pyrimidone et leur utilisation dans le traitement, l'amélioration ou la prévention d'une maladie virale | |
| MA34451B1 (fr) | Dérivés de l'indolizine, procédé pour leur préparation, et leur utilisation thérapeutique | |
| PH12018550049A1 (en) | Protein kinase inhibitor, preparation method and medical use thereof | |
| BR112014003237A2 (pt) | compostos de indazol, composições e métodos de uso | |
| MA37142A3 (fr) | Dérivés de dihydro-benzo-oxazine et de dihydro-pyrido-oxazine | |
| PH12014500326B1 (en) | Heterocyclic derivative and pharmaceutical drug | |
| MA39995B1 (fr) | Composés destinés à traiter l'amyotrophie spinale | |
| JP2016506960A5 (fr) | ||
| MA37400B1 (fr) | Composés hétérocyclyle en tant qu'inhibiteurs de mek | |
| EA201591753A1 (ru) | 3-пиримидин-4-илоксазолидин-2-оны в качестве ингибиторов мутантного idh | |
| EA201391029A1 (ru) | Производные оксазина и их применение при лечении неврологических нарушений | |
| BR112015003380A2 (pt) | composto de pirazolopirimidina | |
| JP2016513130A5 (fr) | ||
| MA38935B1 (fr) | Dérivés de diazacarbazole à titre de ligands tau-pet | |
| GEAP201914608A (en) | Fused bicyclic heteroaryl derivatives having activity as phd inhibitors | |
| ME02840B (fr) | Composés phénoxyéthyl pipéridine | |
| MX381440B (es) | Composicion farmaceutica para tratar colitis ulcerativa. | |
| EA201692298A1 (ru) | Производные карбоксамидов | |
| PH12020551297A1 (en) | Compounds having s1p5 receptor agonistic activity | |
| MA35878B1 (fr) | Utilisation thérapeutique de dérivés d'imidazopyridine | |
| MA35347B1 (fr) | Procedes therapeuiques | |
| MA38229A1 (fr) | Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments | |
| AR113995A1 (es) | Moduladores de molécula pequeña del domino de btb de keap1 | |
| EA202091481A1 (ru) | Замещенные алкиниленовые соединения в качестве противораковых агентов |